Zobrazeno 1 - 10
of 816
pro vyhledávání: '"Stan F"'
Autor:
Remco Kersten, David C. Trampert, Lowiek M. Hubers, Dagmar Tolenaars, Harmjan R. Vos, Stan F. J. van de Graaf, Ulrich Beuers
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Background and aimsIgG4-related cholangitis (IRC) is the hepatobiliary manifestation of IgG4-related disease, a systemic B cell-driven fibro-inflammatory disorder. Four autoantigens have recently been described in IgG4-RD: annexin A11, galectin-3, la
Externí odkaz:
https://doaj.org/article/9a8c0afbbd31453fad841b7992688e02
Autor:
Claudia Sacchetto, Laura Peretto, Francisco Baralle, Iva Maestri, Francesca Tassi, Francesco Bernardi, Stan F. J. van de Graaf, Franco Pagani, Mirko Pinotti, Dario Balestra
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-12 (2021)
Abstract Background Aberrant splicing is a common outcome in the presence of exonic or intronic variants that might hamper the intricate network of interactions defining an exon in a specific gene context. Therefore, the evaluation of the functional,
Externí odkaz:
https://doaj.org/article/d971a21a3803407a8ffea7a8c1a6edd7
Autor:
Stan F. S. P. Looijmans, Michelle M. A. Spanjaards, Ljiljana Puskar, Dario Cavallo, Patrick D. Anderson, Lambèrt C. A. van Breemen
Publikováno v:
Polymers, Vol 14, Iss 22, p 4850 (2022)
Fiber-reinforced polymer composites are largely employed for their improved strength with respect to unfilled matrices. Considering semi-crystalline materials under relevant processing conditions, the applied pressure and flow induce shear stresses a
Externí odkaz:
https://doaj.org/article/07e28a8049b844e18236e6e69cc1b515
Autor:
Marileen M. C. Prins, Francesca P. Giugliano, Manon van Roest, Stan F. J. van de Graaf, Pim J. Koelink, Manon E. Wildenberg
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 4 (2021)
The ATG16L1 T300A single-nucleotide polymorphism (SNP) is associated with Crohn's disease and causes an autophagy impairment. We have previously shown that this SNP is involved in the migration and hyperactivation of Rac1 in dendritic cells. Mucosal
Externí odkaz:
https://doaj.org/article/cdc70577f24c46a7ab8a426149830b6d
Autor:
Remco van Dijk, Sem J. Aronson, Dirk R. de Waart, Stan F. van de Graaf, Suzanne Duijst, Jurgen Seppen, Ronald Oude Elferink, Ulrich Beuers, Piter J. Bosma
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract We aimed to identify potent biliverdin reductase (BVRA) inhibitors as a novel concept for the treatment of severe unconjugated hyperbilirubinemia. 1280 FDA-approved compounds were screened in vitro for their ability to inhibit human and rat
Externí odkaz:
https://doaj.org/article/d12f4548a8564f6a914ed21b89937903
Autor:
Dario Balestra, Mattia Ferrarese, Silvia Lombardi, Nicole Ziliotto, Alessio Branchini, Naomi Petersen, Piter Bosma, Mirko Pinotti, Stan F. J. van de Graaf
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8735 (2020)
OTC splicing mutations are generally associated with the severest and early disease onset of ornithine transcarbamylase deficiency (OTCD), the most common urea cycle disorder. Noticeably, splicing defects can be rescued by spliceosomal U1snRNA varian
Externí odkaz:
https://doaj.org/article/50248ec1b1fc4dbe9b6fc0e3b5124a92
Autor:
Dario Balestra, Daniela Scalet, Mattia Ferrarese, Silvia Lombardi, Nicole Ziliotto, Chrystal C. Croes, Naomi Petersen, Piter Bosma, Federico Riccardi, Franco Pagani, Mirko Pinotti, Stan F. J. van de Graaf
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2136 (2020)
The elucidation of aberrant splicing mechanisms, frequently associated with disease has led to the development of RNA therapeutics based on the U1snRNA, which is involved in 5′ splice site (5′ss) recognition. Studies in cellular models have demon
Externí odkaz:
https://doaj.org/article/7d2b03228a504040b8b832911c05fb85
Autor:
Monique D Appelman, Anindita Chakraborty, Ulrike Protzer, Jane A McKeating, Stan F J van de Graaf
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170419 (2017)
The sodium/bile acid cotransporter NTCP was recently identified as a receptor for hepatitis B virus (HBV). NTCP is glycosylated and the role of glycans in protein trafficking or viral receptor activity is not known. NTCP contains two N-linked glycosy
Externí odkaz:
https://doaj.org/article/aec617ab6d5a49679c3aeff70de4bd8e
Autor:
Niels J H M Gerrits, Anita C van Loenhoud, Stan F van den Berg, Henk W Berendse, Elisabeth M J Foncke, Martin Klein, Diederick Stoffers, Ysbrand D van der Werf, Odile A van den Heuvel
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148852 (2016)
Parkinson's disease (PD) is often associated with cognitive deficits, although their severity varies considerably between patients. Recently, we used voxel-based morphometry (VBM) to show that individual differences in gray matter (GM) volume relate
Externí odkaz:
https://doaj.org/article/2a839c7ab0aa41a5a7d412e9ee6155a6
Autor:
Chudy, Stan F. J.1 (AUTHOR) s.f.j.chudy@amsterdamumc.nl, Phanzu, Delphin M.2,3 (AUTHOR), Kolk, Arend H. J.1 (AUTHOR), Sopoh, Ghislain E.4 (AUTHOR), Barogui, Yves T.5 (AUTHOR), Tzfadia, Oren6 (AUTHOR), Eddyani, Miriam7 (AUTHOR), Fissette, Krista6 (AUTHOR), de Jong, Bouke C.6 (AUTHOR), Brinkman, Paul1 (AUTHOR)
Publikováno v:
PLoS Neglected Tropical Diseases. 9/23/2024, Vol. 18 Issue 9, p1-16. 16p.