Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stan Barone"'
Autor:
Kristi Pullen Fedinick, Gina Solomon, Stan Barone, John J. Vandenberg, John R. Bucher, Kevin C. Elliott, Gary L. Ginsberg
Publikováno v:
Environmental health perspectives, vol 127, iss 12
Environmental Health Perspectives
Environmental Health Perspectives
Background: Numerous types of rapid toxicity or exposure assays and platforms are providing information relevant to human hazard and exposure identification. They offer the promise of aiding decision-making in a variety of contexts including the regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebee2ee7b97a0651329ef9816d664f44
https://doi.org/10.1289/ehp4745
https://doi.org/10.1289/ehp4745
Autor:
Steven O. Simmons, Sigmund J. Degitz, Joseph E. Tietge, Susan C. Laws, Jonathan T. Haselman, Kevin M. Crofton, Michael W. Hornung, Tammy E. Stoker, Pamela D. Noyes, Patience Browne, Katie Paul Friedman, Mary E. Gilbert, Stan Barone
Publikováno v:
Environmental Health Perspectives
Background: Extensive clinical and experimental research documents the potential for chemical disruption of thyroid hormone (TH) signaling through multiple molecular targets. Perturbation of TH signaling can lead to abnormal brain development, cognit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1666bd79e1fbad555d42289de3f5f71a
https://pubmed.ncbi.nlm.nih.gov/31487205
https://pubmed.ncbi.nlm.nih.gov/31487205
Publikováno v:
Human and Ecological Risk Assessment: An International Journal. 7:1091-1120
Biologically based dose-response (BBDR) models predict health outcomes (response) resulting from the presence of a toxicant at a biological target (dose). The benefits of BBDR models are many, and research programs are increasingly focusing on mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::589c441a99c436909fa2a46f9ade6e90
https://doi.org/10.1080/20018091094871
https://doi.org/10.1080/20018091094871
Autor:
Deborah C. Rice, Stan Barone
Publikováno v:
Environmental Health Perspectives
Vulnerable periods during the development of the nervous system are sensitive to environmental insults because they are dependent on the temporal and regional emergence of critical developmental processes (i.e., proliferation, migration, differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c024b29d2a51163747529ba8bffc95
https://doi.org/10.1289/ehp.00108s3511
https://doi.org/10.1289/ehp.00108s3511
Publikováno v:
Toxicological Sciences. 23:447-464
Developmental Neurotoxicity: Evaluation of Testing Procedures with Methylazoxymethanol and Methylmercury. Goldey, E. S., O'Callaghan, J. P., Stanton, M. E., Barone, S., Jr., and Crofton, K. M. (1994). Fundam. Appl. Toxicol. 23, 447-464. Testing proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ffe3e8fb3cdbb72249698e2a64c68b
https://doi.org/10.1093/toxsci/23.3.447
https://doi.org/10.1093/toxsci/23.3.447
Publikováno v:
Brain Research. 634:85-95
Long-Evans rat pups were injected i.p. on postnatal day 5 (PND5) or 12 with 0, 3, or 5 mg/kg triethyltin sulfate (TET) and then tested on T-maze delayed alternation on PND21 or 28. Delayed alternation learning was impaired on PND21 and 28 in pups giv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbc955bb68d3c4081ef6fcbaa42380b
https://doi.org/10.1016/0006-8993(94)90261-5
https://doi.org/10.1016/0006-8993(94)90261-5
Publikováno v:
Toxicology and applied pharmacology. 255(1)
The potential for central nervous system depressant effects from three widely used chlorinated solvents, trichloroethylene (TCE), perchloroethylene (PERC), and dichloromethane (DCM), has been shown in human and animal studies. Commonalities of neurob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e418347fe2ecffb4880000726ee1e89
https://pubmed.ncbi.nlm.nih.gov/21609728
https://pubmed.ncbi.nlm.nih.gov/21609728
Publikováno v:
Neurotoxicity research. 1(4)
Neurotrophin-stimulated signal transduction through the Trk receptors has been implicated in the development and survival of the nervous system. Phospholipase Cgamma (PLCgamma) is an early downstream effector for the Trk receptors, and catalyzes the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6864615ac7344abcbeb1ff128406779c
https://pubmed.ncbi.nlm.nih.gov/12835095
https://pubmed.ncbi.nlm.nih.gov/12835095
Autor:
Rossanne M Philen, Jane Adams, Stan Barone, Anthony LaMantia, Ezra Susser, Deborah C. Rice, Linda Spear
Publikováno v:
Environmental Health Perspectives
This paper summarizes the deliberations of a work group charged with addressing specific questions relevant to risk estimation in developmental neurotoxicology. We focused on eight questions. a) Does it make sense to think about discrete windows of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5e31d4fb13f0846279847996a2b9ec
Publikováno v:
Brain research. Developmental brain research. 109(1)
Protein kinase C (PKC)-mediated phosphorylation has been implicated in neuronal growth and differentiation [R.S. Turner, R.L. Mazzei, G.J. Raynor, P.R. Girard, J.F. Kuo, Proc. Natl. Acad. Sci. U.S.A., 81 (1984) 3143-3147.]. We examined effects of ges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38adca1822d49f4af549ac26cb3e9473
https://pubmed.ncbi.nlm.nih.gov/9706389
https://pubmed.ncbi.nlm.nih.gov/9706389