Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways.

Autor: Spain L; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom.; Department of Medical Oncology, Peter MacCallum Cancer -Centre, Melbourne, Australia., Coulton A; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Tumour Immunogenomics and Immunosurveillance (TIGI) Lab, UCL Cancer Institute, London, United Kingdom., Lobon I; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Rowan A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, United Kingdom., Schnidrig D; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Shepherd STC; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Shum B; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Byrne F; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Goicoechea M; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Piperni E; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Au L; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom.; Department of Medical Oncology, Peter MacCallum Cancer -Centre, Melbourne, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, Australia., Edmonds K; The Royal Marsden Hospital, London, United Kingdom., Carlyle E; The Royal Marsden Hospital, London, United Kingdom., Hunter N; The Royal Marsden Hospital, London, United Kingdom., Renn A; The Royal Marsden Hospital, London, United Kingdom., Messiou C; The Royal Marsden Hospital, London, United Kingdom.; The Institute of Cancer Research, Kensington and Chelsea, United Kingdom., Hughes P; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Nobbs J; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Foijer F; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., van den Bos H; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Wardenaar R; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Spierings DCJ; European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Spencer C; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Schmitt AM; The Royal Marsden Hospital, London, United Kingdom., Tippu Z; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Lingard K; The Royal Marsden Hospital, London, United Kingdom., Grostate L; The Royal Marsden Hospital, London, United Kingdom., Peat K; The Royal Marsden Hospital, London, United Kingdom., Kelly K; The Royal Marsden Hospital, London, United Kingdom., Sarker S; The Royal Marsden Hospital, London, United Kingdom., Vaughan S; The Royal Marsden Hospital, London, United Kingdom., Mangwende M; The Royal Marsden Hospital, London, United Kingdom., Terry L; The Royal Marsden Hospital, London, United Kingdom., Kelly D; The Royal Marsden Hospital, London, United Kingdom., Biano J; The Royal Marsden Hospital, London, United Kingdom., Murra A; The Royal Marsden Hospital, London, United Kingdom., Korteweg J; The Royal Marsden Hospital, London, United Kingdom., Lewis C; The Royal Marsden Hospital, London, United Kingdom., O'Flaherty M; The Royal Marsden Hospital, London, United Kingdom., Cattin AL; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Emmerich M; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; St. John's Institute of Dermatology, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom., Gerard CL; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Precision Oncology Center, Oncology Department, Lausanne University Hospital, Lausanne, Switzerland., Pallikonda HA; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom., Lynch J; The Royal Marsden Hospital, London, United Kingdom., Mason R; Gold Coast University Hospital, Queensland, Australia., Rogiers A; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; The Royal Marsden Hospital, London, United Kingdom., Xu H; The Francis Crick Institute, London, United Kingdom., Huebner A; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, United Kingdom.; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom.; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom., McGranahan N; Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom., Al Bakir M; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, United Kingdom.; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom., Murai J; Tumour Immunogenomics and Immunosurveillance (TIGI) Lab, UCL Cancer Institute, London, United Kingdom.; Drug Discovery Technology Laboratories, Ono Pharmaceutical Co., Ltd. Osaka, Japan., Naceur-Lombardelli C; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom., Borg E; University College London Hospital, London, United Kingdom., Mitchison M; University College London Hospital, London, United Kingdom., Moore DA; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Falzon M; University College London Hospital, London, United Kingdom., Proctor I; University College London Hospital, London, United Kingdom., Stamp GWH; The Francis Crick Institute, London, United Kingdom., Nye EL; The Francis Crick Institute, London, United Kingdom., Young K; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Furness AJS; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom.; The Institute of Cancer Research, Kensington and Chelsea, United Kingdom., Pickering L; The Royal Marsden Hospital, London, United Kingdom., Stewart R; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Mahadeva U; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Green A; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Larkin J; Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Litchfield K; Tumour Immunogenomics and Immunosurveillance (TIGI) Lab, UCL Cancer Institute, London, United Kingdom., Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, United Kingdom., Jamal-Hanjani M; Cancer Research UK Lung Cancer Centre of Excellence, UCL Cancer Institute, London, United Kingdom.; Cancer Metastasis Laboratory, University College London Cancer Institute, London, United Kingdom.; Department of Medical Oncology, University College London Hospitals, London, United Kingdom., Turajlic S; Cancer Dynamics Laboratory, The Francis Crick Institute, London, United Kingdom.; Skin and Renal Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom.

Publikováno v: Cancer discovery [Cancer Discov] 2023 Jun 02; Vol. 13 (6), pp. 1364-1385.

ATMIN Is a Tumor Suppressor Gene in Lung Adenocarcinoma.

Autor: Foster H; Adult Stem Cell Laboratory, The Francis Crick Institute, London, United Kingdom.; Tomas Lindahl Nobel Laureate Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China., Ruiz EJ; Adult Stem Cell Laboratory, The Francis Crick Institute, London, United Kingdom., Moore C; Oncogene Biology Laboratory, The Francis Crick Institute, London, United Kingdom., Stamp GWH; Experimental Histopathology Laboratory, The Francis Crick Institute, London, United Kingdom., Nye EL; Experimental Histopathology Laboratory, The Francis Crick Institute, London, United Kingdom., Li N; Adult Stem Cell Laboratory, The Francis Crick Institute, London, United Kingdom.; Tomas Lindahl Nobel Laureate Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China., Pan Y; Tomas Lindahl Nobel Laureate Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China., He Y; Tomas Lindahl Nobel Laureate Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China., Downward J; Oncogene Biology Laboratory, The Francis Crick Institute, London, United Kingdom., Behrens A; Adult Stem Cell Laboratory, The Francis Crick Institute, London, United Kingdom. axel.behrens@crick.ac.uk.; School of Medicine, King's College London, Guy's Campus, London, United Kingdom.

Publikováno v: Cancer research [Cancer Res] 2019 Oct 15; Vol. 79 (20), pp. 5159-5166. Date of Electronic Publication: 2019 Sep 03.

Anoikis related genes may be novel markers associated with prognosis for ovarian cancer.

Autor: Yang, Chen¹ (AUTHOR), Zhu, LuChao¹ (AUTHOR), Lin, Qin¹ (AUTHOR) linqin05@163.com

Publikováno v: Scientific Reports. 1/18/2024, Vol. 13 Issue 1, p1-12. 12p.

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