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Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors.

Autor: Stamatouli, Angeliki M., Quandt, Zoe, Perdigoto, Ana Luisa, Clark, Pamela L., Kluger, Harriet, Weiss, Sarah A., Gettinger, Scott, Sznol, Mario, Young, Arabella, Rushakoff, Robert, Lee, James, Bluestone, Jeffrey A., Anderson, Mark, Herold, Kevan C.

Publikováno v: Diabetes; Aug2018, Vol. 67 Issue 8, p1471-1480, 10p

Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma.

Autor: Floros KV; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298 USA., Fairchild CK Jr; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Pauley Heart Center, Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA., Li J; University of Utah, Huntsman Cancer Institute, 2000 Circle of Hope Drive, Salt Lake City, UT 84112 USA., Zhang K; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298 USA., Roberts JL; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298 USA., Kurupi R; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Division of Oncology, Department of Internal Medicine, Washington University School of Medicine Saint Louis, MO 63110 USA., Hu B; Department of Pathology, Virginia Commonwealth University and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA., Kraskauskiene V; Department of Pathology, Virginia Commonwealth University and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA., Hosseini N; Department of Pathology, Virginia Commonwealth University and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA., Shen S; Department of Pathology, Virginia Commonwealth University and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA., Inge MM; Department of Biology, Boston University, Boston, MA 02215, USA.; Biological Design Center, Boston University, Boston, MA 02215, USA., Smith-Fry K; University of Utah, Huntsman Cancer Institute, 2000 Circle of Hope Drive, Salt Lake City, UT 84112 USA., Li L; University of Utah, Huntsman Cancer Institute, 2000 Circle of Hope Drive, Salt Lake City, UT 84112 USA., Sotiriou A; Soft Tissue Sarcoma Research Group, Hopp Children's Cancer Center, Heidelberg (KiTZ), German Cancer Research Center (DKFZ), Heidelberg, Germany., Dalton KM; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298 USA., Jose A; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Renal Section, Department of Medicine, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA., Abdelfadiel EI; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298 USA., Xing Y; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298 USA., Hill RD; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298 USA., Slaughter JM; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298 USA., Shende M; Department of Pathology, Virginia Commonwealth University and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA., Lorenz MR; Department of Pathology, Virginia Commonwealth University and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA., Hinojosa MR; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, USA.; Department of Molecular Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Belvin BR; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA., Lai Z; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, USA.; Department of Molecular Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Boikos SA; Department of Hematology and Oncology, Georgetown Lombardi Comprehensive Cancer Center, 3800 Reservoir Rd NW Ste E501, Washington, DC 20007 USA., Stamatouli AM; Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia USA., Lewis JP; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Biochemistry and Molecular Biology, and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, 23298, USA.; Department of Microbiology & Immunology and Massey Cancer Center, Richmond VA, USA., Manjili MH; Department of Microbiology & Immunology and Massey Cancer Center, Richmond VA, USA., Valerie K; Department of Radiation Oncology and Massey Comprehensive Cancer Center, Virginia Commonwealth University, Richmond VA, 23298 USA., Li R; Program in Microbiology and Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Cancer Virology Program, Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA., Banito A; Soft Tissue Sarcoma Research Group, Hopp Children's Cancer Center, Heidelberg (KiTZ), German Cancer Research Center (DKFZ), Heidelberg, Germany., Poklepovic A; Department of Internal Medicine, Division of Oncology, Massey Comprehensive Cancer Center, Virginia Commonwealth University, Richmond, VA, USA., Koblinski JE; Department of Pathology, Virginia Commonwealth University and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA., Siggers T; Department of Biology, Boston University, Boston, MA 02215, USA.; Biological Design Center, Boston University, Boston, MA 02215, USA.; Bioinformatics Program, Boston University, Boston, MA 02215, USA., Dozmorov MG; Department of Biostatistics, Virginia Commonwealth University, Richmond VA, 23298 USA., Jones KB; University of Utah, Huntsman Cancer Institute, 2000 Circle of Hope Drive, Salt Lake City, UT 84112 USA., Radhakrishnan SK; Department of Pathology, Virginia Commonwealth University and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA., Faber AC; VCU Philips Institute, Virginia Commonwealth University School of Dentistry and Massey Comprehensive Cancer Center, Richmond VA, 23298 USA.; Department of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298 USA.

Publikováno v: Research square [Res Sq] 2024 Jun 06. Date of Electronic Publication: 2024 Jun 06.

Elective Colectomy in a Patient with Active Ulcerative Colitis and Metastatic Melanoma Enabling Successful Treatment with Immune Checkpoint Inhibitors.

Autor: Perdigoto AL; Section of Endocrinology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Tran T; Section of Medical Oncology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Patel N; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA., Clark P; Department of Immunobiology, Yale University, New Haven, Connecticut, USA., Patell K; Section of Medical Oncology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Stamatouli AM; Section of Endocrinology, Virginia Commonwealth University, Richmond, Virginia, USA., Reddy V; Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA., Clune J; Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA., Herold KC; Section of Endocrinology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Immunobiology, Yale University, New Haven, Connecticut, USA., Robert ME; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA., Kluger HM; Section of Medical Oncology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.

Publikováno v: Clinical oncology, case reports [Clin Oncol Case Rep] 2020 Nov; Vol. 3 (5). Date of Electronic Publication: 2020 Sep 17.