The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade.

Autor: Qiu Y; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Stamatatos OT; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Hu Q; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Graduate Program in Genetics, Stony Brook University, Stony Brook, NY, USA., Ruiter Swain J; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; CSHL School of Biological Sciences, Cold Spring Harbor, NY, USA., Russo S; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Sann A; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Costa ASH; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.; Matterworks Inc., Somerville, MA, USA., Violante S; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Spector DL; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Cross JR; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lukey MJ; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. lukey@cshl.edu.

Publikováno v: Nature metabolism [Nat Metab] 2024 Aug; Vol. 6 (8), pp. 1529-1548. Date of Electronic Publication: 2024 Aug 27.