Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Stafford, D W"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2006 Dec . 103(51), 19308-19313.
Externí odkaz:
https://www.jstor.org/stable/30051296
Autor:
McGraw, R. A., Davis, L. M., Noyes, C. M., Lundblad, R. L., Roberts, H. R., Graham, J. B., Stafford, D. W.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1985 May 01. 82(9), 2847-2851.
Externí odkaz:
https://www.jstor.org/stable/25275
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1964 Aug . 52(2), 313-316.
Externí odkaz:
https://www.jstor.org/stable/72440
Single nucleotide polymorphisms in the vitamin K epoxide reductase (VKOR) gene have been successfully used for warfarin dosage prediction. However, warfarin resistance studies of naturally occurring VKOR mutants do not correlate with their clinical p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32079c2e39cba46cf4d5f4b2703af577
Akademický článek
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Autor:
Stafford, D. W., Iverson, R. M.
Publikováno v:
Science, 1964 Feb 01. 143(3606), 580-581.
Externí odkaz:
https://www.jstor.org/stable/1713633
More than 21 million prescriptions for warfarin are written yearly in the U.S. Despite its importance, warfarin's target, vitamin K epoxide reductase (VKOR), has resisted purification since its identification in 1972. Here, we report its purification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c83ef449b3a92468899bdd932549d2b7
Autor:
Stafford, D. W., Pleasant, W. A., Hatada, S., Fair, J. H., Smithies, O., Kim, H.-s., LaPaglia, M. A., Cairns, B. A., Meyer, A. A., Frelinger, J. A., Gui, T., Caballero, M., Pevny, L.
Murine embryonic stem (ES) cells are pluripotent, but significant functional engraftment does not occur when they are introduced into the liver. However, here we demonstrate that functional liver engraftment does occur if the ES cells (from strain 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bacb6e574e5c82c7b4bbf7d0198d0a0
Autor:
Azerad, R., Solera, J., Stafford, D. W., Mutucumarana, V. P., Jin, D. Y., Wu, S. M., Brenner, B., Stanley, T. B.
Patients with mutation L394R in gamma-glutamyl carboxylase have a severe bleeding disorder because of decreased biological activities of all vitamin K-dependent coagulation proteins. Vitamin K administration partially corrects this deficiency. To cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fcc7cfbe2d6a0d672658e66c8ceba12
Vitamin K-dependent proteins contain a propeptide that is required for recognition by the enzyme gamma-glutamylcarboxylase. Substrates used in vitro for carboxylation studies lacking a prosequence are characterized by Km values in the millimolar rang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::affa3e0be804fe7ba6fd8d8aa7806e7e
https://europepmc.org/articles/PMC1220355/
https://europepmc.org/articles/PMC1220355/