Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Staffan Svärd"'
Autor:
Faruk Dube, Nicolas Delhomme, Frida Martin, Andrea Hinas, Magnus Åbrink, Staffan Svärd, Eva Tydén
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298039 (2024)
Anthelmintic resistance in equine parasite Parascaris univalens, compromises ivermectin (IVM) effectiveness and necessitates an in-depth understanding of its resistance mechanisms. Most research, primarily focused on holistic gene expression analyses
Externí odkaz:
https://doaj.org/article/dd9ae23839524cc5b57965a61a46916c
Autor:
Alžběta Motyčková, Luboš Voleman, Vladimíra Najdrová, Lenka Arbonová, Martin Benda, Vít Dohnálek, Natalia Janowicz, Ronald Malych, Róbert Šuťák, Thijs J G Ettema, Staffan Svärd, Courtney W Stairs, Pavel Doležal
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1010773 (2023)
Mitochondrial metabolism is entirely dependent on the biosynthesis of the [4Fe-4S] clusters, which are part of the subunits of the respiratory chain. The mitochondrial late ISC pathway mediates the formation of these clusters from simpler [2Fe-2S] mo
Externí odkaz:
https://doaj.org/article/16b4df0815e745b29687962ec20e8cbb
Autor:
Rui Santos, Ásgeir Ástvaldsson, Shweta V. Pipaliya, Jon Paulin Zumthor, Joel B. Dacks, Staffan Svärd, Adrian B. Hehl, Carmen Faso
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Giardia lamblia, a parasitic protist of the Metamonada supergroup, has evolved one of the most diverged endocytic compartment systems investigated so far. Peripheral endocytic compartments, currently known as peripheral vesicles o
Externí odkaz:
https://doaj.org/article/935919f8ee174cad894572d8814a70b2
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-15 (2022)
Abstract Background The nematode Parascaris univalens is one of the most prevalent parasitic pathogens infecting horses but anthelmintic resistance undermines treatment approaches. The molecular mechanisms underlying drug activity and resistance rema
Externí odkaz:
https://doaj.org/article/fc59d0de2bd24ffaaf4b0147e0325e8c
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285262 (2023)
Parasitic nematodes pose a significant threat to human and animal health, as well as cause economic losses in the agricultural sector. The use of anthelmintic drugs, such as Ivermectin (IVM), to control these parasites has led to widespread drug resi
Externí odkaz:
https://doaj.org/article/e536f8a9fba7409f81d152e6f4b1e37e
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Metronidazole (MTZ) is a clinically important antimicrobial agent that is active against both bacterial and protozoan organisms. MTZ has been used extensively for more than 60 years and until now resistance has been rare. However, a recent and dramat
Externí odkaz:
https://doaj.org/article/cca44e03107d4c2b9e36c801a3515b2e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The proteoglycan serglycin (SG) is expressed by different innate and adaptive immune cells, e.g. mast cells, macrophages, neutrophils, and cytotoxic T lymphocytes, where SG contributes to correct granule storage and extracellular activity of inflamma
Externí odkaz:
https://doaj.org/article/f919aba35a65431b8e80b3e822fcffff
Autor:
Courtney W. Stairs, Anna Kokla, Ásgeir Ástvaldsson, Jon Jerlström-Hultqvist, Staffan Svärd, Thijs J. G. Ettema
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-21 (2019)
Abstract Background Spironucleus salmonicida is an anaerobic parasite that can cause systemic infections in Atlantic salmon. Unlike other diplomonad parasites, such as the human pathogen Giardia intestinalis, Spironucleus species can infiltrate the b
Externí odkaz:
https://doaj.org/article/dcf59558722148e28d8c7deb8f815e22
Publikováno v:
Cells, Vol 9, Iss 4, p 925 (2020)
Mast cells have been shown to affect the control of infections with the protozoan parasite Giardia intestinalis. Recently, we demonstrated that Giardia excretory-secretory proteins inhibited the activity of the connective tissue mast cell-specific pr
Externí odkaz:
https://doaj.org/article/e722cf1ceb6a4e5fb2013eb79f085bf2
Autor:
Alžběta Motyčková, Luboš Voleman, Vladimíra Najdrová, Lenka Marková, Martin Benda, Vít Dohnálek, Natalia Janowicz, Ronald Malych, Róbert Šuťák, Thijs J. G. Ettema, Staffan Svärd, Courtney W. Stairs, Pavel Doležal
Mitochondrial metabolism is entirely dependent on the biosynthesis of the [4Fe-4S] clusters, which are part of the subunits of the respiratory chain. The mitochondrial late ISC pathway mediates the formation of these clusters from simpler [2Fe-2S] mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68677ab564ee0137d3d55ad210e70bf0
https://doi.org/10.1101/2022.08.01.502261
https://doi.org/10.1101/2022.08.01.502261