Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Staffan Holmberg-Thydén"'
Autor:
Sunil Kumar Saini, Andreas Due Ørskov, Anne-Mette Bjerregaard, Ashwin Unnikrishnan, Staffan Holmberg-Thydén, Annie Borch, Kathrine Valentini Jensen, Govardhan Anande, Amalie Kai Bentzen, Andrea Marion Marquard, Tripti Tamhane, Marianne Bach Treppendahl, Anne Ortved Gang, Inge Høgh Dufva, Zoltan Szallasi, Nicola Ternette, Anders Gorm Pedersen, Aron Charles Eklund, John Pimanda, Kirsten Grønbæk, Sine Reker Hadrup
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Human endogenous retroviruses (HERV) normally remain quiescent, but can be reactivated by malignant transformation. Here the authors find, via HERV peptide library testing and tetramer validation, more profound HERV transcription and associated T cel
Externí odkaz:
https://doaj.org/article/d34a194f6b844353a08c2553d7fdeaee
Autor:
Sunil Kumar Saini, Staffan Holmberg-Thydén, Anne-Mette Bjerregaard, Ashwin Unnikrishnan, Simon Dorfmüller, Uwe Platzbecker, Irene Tirado-Gonzalez, Halvard Bönig, Daniel El Fassi, Kirsten Grønbæk, John Pimanda, Hind Medyouf, Sine Reker Hadrup
Publikováno v:
Saini, S K, Holmberg-Thydén, S, Bjerregaard, A M, Unnikrishnan, A, Dorfmüller, S, Platzbecker, U, Tirado-Gonzalez, I, Bönig, H, El Fassi, D, Grønbæk, K, Pimanda, J, Medyouf, H & Hadrup, S R 2022, ' Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies ', Leukemia, vol. 36, no. 11, pp. 2734-2738 . https://doi.org/10.1038/s41375-022-01705-y
Autor:
Kirsten Grønbæk, Staffan Holmberg-Thydén, Sine Reker Hadrup, Anne Ortved Gang, Daniel El Fassi
Publikováno v:
Holmberg-Thyden, S, Grønbæk, K, Gang, A O, El Fassi, D & Hadrup, S R 2021, ' A user's guide to multicolor flow cytometry panels for comprehensive immune profiling ', Analytical Biochemistry, vol. 627, 114210 . https://doi.org/10.1016/j.ab.2021.114210
Multicolor flow cytometry is an essential tool for studying the immune system in health and disease, allowing users to extract longitudinal multiparametric data from patient samples. The process is complicated by substantial variation in performance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a6d955e40decd1f9fb77056fdadc91
https://orbit.dtu.dk/en/publications/01311655-7d11-4e51-8557-479e8e325f31
https://orbit.dtu.dk/en/publications/01311655-7d11-4e51-8557-479e8e325f31
Autor:
Anne Ortved Gang, Kirsten Grønbæk, Mette K. Andersen, Marie Fredslund Breinholt, Mohammad Kadivar, Inge Marie Svane, Staffan Holmberg-Thydén, Sine Reker Hadrup, Lone Schejbel, Daniel El Fassi, Inge Høgh Dufva
Publikováno v:
Cancer immunology, immunotherapy : CII. 71(2)
Standard care for patients with high-risk myelodysplastic syndrome (MDS) is hypomethylating agents such as azacitidine (AZA), which can induce expression of methylated tumor-associated antigens and therefore potentiate immunotherapeutic targeting. In
Autor:
John E. Pimanda, Anne-Mette Bjerregaard, Andrea Marion Marquard, Kirsten Grønbæk, Aron Charles Eklund, Sine Reker Hadrup, Kathrine Valentini Jensen, Staffan Holmberg-Thydén, Anne Ortved Gang, Inge Høgh Dufva, Zoltan Szallasi, Ashwin Unnikrishnan, Amalie Kai Bentzen, Nicola Ternette, Tripti Tamhane, Annie Borch, Andreas Due Ørskov, Govardhan Anande, Marianne Bach Treppendahl, Sunil Kumar Saini, Anders Gorm Pedersen
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Saini, S K, Ørskov, A D, Bjerregaard, A M, Unnikrishnan, A, Holmberg-Thydén, S, Borch, A, Jensen, K V, Anande, G, Bentzen, A K, Marquard, A M, Tamhane, T, Treppendahl, M B, Gang, A O, Dufva, I H, Szallasi, Z, Ternette, N, Pedersen, A G, Eklund, A C, Pimanda, J, Grønbæk, K & Hadrup, S R 2020, ' Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers ', Nature Communications, vol. 11, no. 1, 5660 . https://doi.org/10.1038/s41467-020-19464-8
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Saini, S K, Ørskov, A D, Bjerregaard, A M, Unnikrishnan, A, Holmberg-Thydén, S, Borch, A, Jensen, K V, Anande, G, Bentzen, A K, Marquard, A M, Tamhane, T, Treppendahl, M B, Gang, A O, Dufva, I H, Szallasi, Z, Ternette, N, Pedersen, A G, Eklund, A C, Pimanda, J, Grønbæk, K & Hadrup, S R 2020, ' Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers ', Nature Communications, vol. 11, no. 1, 5660 . https://doi.org/10.1038/s41467-020-19464-8
Human endogenous retroviruses (HERV) form a substantial part of the human genome, but mostly remain transcriptionally silent under strict epigenetic regulation, yet can potentially be reactivated by malignant transformation or epigenetic therapies. H
Autor:
Marie Fredslund Breinholt, Staffan Holmberg-Thydén, Mohammad Kadivar, Inge Høgh Dufva, Daniel El Fassi, Inge Marie Svane, Kirsten Grønbæk, Mette K. Andersen, Sine Reker Hadrup, Lone Schejbel, Anne Ortved Gang
Publikováno v:
Blood. 136:23-24
Background: Standard care for patients with high risk myelodysplastic syndrome (MDS) is hypomethylating agents, such as azacitidine (AZA). AZA can induce expression of silenced genes, including methylated tumor associated antigens. Such tumor associa