Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Staffan Arvidson"'
Autor:
Patric Nilsson, Stefan Karlsson, Peter Sögård, Jan Oscarsson, Staffan Arvidson, Erik Gustafsson
Publikováno v:
International Journal of Medical Microbiology. 299:65-74
In the present work a general systems biology approach has been used to study the complex regulatory network controlling the transcription of the spa gene, encoding protein A, a major surface protein and an important virulence factor of Staphylococcu
Autor:
Helena Enroth, Gunnar Jacobsson, Erik Gustafsson, Staffan Arvidson, Patric Nilsson, Marie Kia Beronius, Rune Andersson
Publikováno v:
Scandinavian Journal of Infectious Diseases. 41:577-583
In the present study, we have investigated 37 invasive Staphylococcus aureus strains (collected between 1997 and 2005) from 33 human episodes of septicaemia causing either endocarditis or vertebral osteomyelitis. All S. aureus strains were typed usin
Publikováno v:
Infection and Immunity. 75:4534-4540
TraP is a triply phosphorylated staphylococcal protein that has been hypothesized to be the mediator of a second Staphylococcus aureus quorum-sensing system, “SQS1,” that controls expression of the agr system and therefore is essential for the or
Publikováno v:
Journal of Bacteriology. 188:8526-8533
In most Staphylococcus aureus strains, inactivation of sarA increases hla transcription, indicating that sarA is a repressor. However, in S. aureus NCTC 8325 and its derivatives, used for most studies of hla regulation, inactivation of sarA resulted
Publikováno v:
International Journal of Medical Microbiology. 296:365-380
Previous studies have shown that production of extracellular proteases in Staphylococcus aureus is stimulated by agr (RNAIII) and mgrA, and repressed by sarA. Protease expression is also repressed by rot, however this effect is generally observed onl
Publikováno v:
International Journal of Medical Microbiology. 296:229-236
It has been reported that high production of proteases and α -hemolysin in the prototype Staphylococcus aureus strain 8325-4 was associated with its σ B deficiency. Here we analyzed one fresh clinical isolate (KS26) and two ancient human isolates (
Publikováno v:
International Journal of Medical Microbiology. 295:253-266
Production of protein A (SpA) in Staphylococcus aureus is controlled by several global regulators including agr (RNAIII), sarA, sarS, sarT, rot and mgrA, which appear to form a regulatory network. SarS, which is an activator of spa, seems to be a key
Publikováno v:
Infection and Immunity. 72:6106-6111
The prototype Staphylococcus aureus strain 8325-4 produces high levels of hemolysins and proteases. Recently it has been shown that this property depends on a deficiency of sigma factor B (SigB) activity controlling the activation of regulatory genes
Autor:
Fionnuala McAleese, Peter J. McNamara, Barry N. Kreiswirth, Timothy J. Foster, Staffan Arvidson, Steven J. Projan, Ellen Murphy, Battouli Saïd-Salim, Paul M. Dunman, D. Macapagal
Publikováno v:
Journal of Bacteriology. 185:610-619
Staphylococcus aureus produces a wide array of cell surface and extracellular proteins involved in virulence. Expression of these virulence factors is tightly controlled by numerous regulatory loci, including agr , sar , sigB , sae , and arl , as wel
Autor:
Staffan Arvidson, Anna Karlsson
Publikováno v:
Infection and Immunity. 70:4239-4246
Staphylococcus aureus produces four major extracellular proteases: staphylococcal serine protease (V8 protease; SspA), cysteine protease (SspB), metalloprotease (aureolysin; Aur), and staphopain (Scp). Several in vitro studies have suggested that the