Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Staffan, Schmidt"'
Autor:
Victoria Schiffer, Estibaliz Santiago-Mujika, Stefanie Flunkert, Staffan Schmidt, Martina Farcher, Tina Loeffler, Irene Schilcher, Maria Posch, Joerg Neddens, Ying Sun, Jan Kehr, Birgit Hutter-Paier
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227077 (2020)
Gaucher disease is caused by a deficiency in glucocerebrosidase that can result in non-neuronal as well as neuronal symptoms. Common visceral symptoms are an increased organ size, specifically of the spleen, and glucosylceramide as well as glucosylsp
Externí odkaz:
https://doaj.org/article/934465be4e504e42abf8e2944f2bd11d
Autor:
Laura Tarnawski, Vladimir S. Shavva, Eric J. Kort, Zhengbing Zhuge, Ingrid Nilsson, Alessandro L. Gallina, David Martínez-Enguita, Benjamin Heller Sahlgren, Matthew Weiland, April S. Caravaca, Staffan Schmidt, Ping Chen, Katarina Abbas, Fu-Hua Wang, Osman Ahmed, Michael Eberhardson, Anna Färnert, Eddie Weitzberg, Mika Gustafsson, Jan Kehr, Stephen G. Malin, Henrik Hult, Mattias Carlström, Stefan Jovinge, Peder S. Olofsson
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Endothelial dysfunction and impaired vasodilation are linked with adverse cardiovascular events. T lymphocytes expressing choline acetyltransferase (ChAT), the enzyme catalyzing biosynthesis of the vasorelaxant acetylcholine (ACh), regulate vasodilat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cb681031febe45afd788f72d0012010
https://doi.org/10.1073/pnas.2212476120
https://doi.org/10.1073/pnas.2212476120
Autor:
Takashi Yoshitake, Souren Mkrtchian, Staffan Schmidt, Anette Ebberyd, Jessica Kåhlin, Lars Eriksson, Jan Kehr, Helena Erlandsson Harris, Marta Gómez-Galán, Malin Jonsson Fagerlund, Malin Hildenborg
Publikováno v:
Experimental Physiology. 105:1634-1647
New findings What is the central question of this study? Are carotid bodies (CBs) modulated by the damage-associated molecular patterns (DAMPs) and humoral factors of aseptic tissue injury? What are the main findings and their importance? DAMPs (HMGB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54339658b0418d4647a9f4a5a4ce46f1
https://doi.org/10.1113/ep088705
https://doi.org/10.1113/ep088705
Autor:
Staffan Schmidt, Joseph T. Coyle, Micaela Galante, Glenn Dallérac, Kevin C. F. Fone, Silvia Sacchi, Grégoire Levasseur, Jan Kehr, David J. G. Watson, Brigitte Potier, Xia Li, Pierre Lecouflet, Alain M. Gardier, Loredano Pollegioni, Thu Ha Pham, Rachel Asselot, Angelo Contarino, Pascal Fossat, Jean-Pierre Mothet, Millan Mark, Andrey Besedin, Ginetta Collo, Thomas Freret, Jean-Michel Rivet, Nadege Morisot
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (23), pp.e2023750118. ⟨10.1073/pnas.2023750118⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, ⟨10.1073/pnas.2023750118⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (23), pp.e2023750118. ⟨10.1073/pnas.2023750118⟩
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (23), pp.e2023750118. ⟨10.1073/pnas.2023750118⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, ⟨10.1073/pnas.2023750118⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (23), pp.e2023750118. ⟨10.1073/pnas.2023750118⟩
Proc Natl Acad Sci U S A
International audience; Prefrontal control of cognitive functions critically depends upon glutamatergic transmission and N-methyl D-aspartate (NMDA) receptors, the activity of which is regulated by dopamine. Yet whether the NMDA receptor coagonist d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e3d40a1a9203362891908b7866e4c8
https://hal.archives-ouvertes.fr/hal-03277751
https://hal.archives-ouvertes.fr/hal-03277751
Autor:
Peixiong Yuan, Jacqueline Lovett, Ruin Moaddel, Timothy A. Troppoli, Craig J. Thomas, Carleigh Jenne, Eric W. Lumsden, Panos Zanos, Fu-Hua Wang, Patrick J. Morris, Edson X. Albuquerque, Staffan Schmidt, Scott J. Myers, Stephen F. Traynelis, Jan Kehr, Scott M. Thompson, Sukhan Kim, Yasco Aracava, Edna F. R. Pereira, Carlos A. Zarate, Todd D. Gould
Publikováno v:
Proceedings of the National Academy of Sciences. 116:5160-5169
Preclinical studies indicate that (2R,6R)-hydroxynorketamine (HNK) is a putative fast-acting antidepressant candidate. Although inhibition of NMDA-type glutamate receptors (NMDARs) is one mechanism proposed to underlie ketamine’s antidepressant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793cdb62a68bc31140f1a2e2443ce37f
https://doi.org/10.1073/pnas.1816071116
https://doi.org/10.1073/pnas.1816071116
Autor:
Ying Sun, Birgit Hutter-Paier, Victoria Schiffer, Tina Loeffler, Martina Farcher, Stefanie Flunkert, Estibaliz Santiago-Mujika, Irene Schilcher, Staffan Schmidt, Joerg Neddens, Maria Posch, Jan Kehr
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0227077 (2020)
PLoS ONE, Vol 15, Iss 1, p e0227077 (2020)
Gaucher disease is caused by a deficiency in glucocerebrosidase that can result in non-neuronal as well as neuronal symptoms. Common visceral symptoms are an increased organ size, specifically of the spleen, and glucosylceramide as well as glucosylsp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbfee898875fc0c39b6c98ff61b7671
http://europepmc.org/articles/PMC6957154
http://europepmc.org/articles/PMC6957154
Autor:
Jatin Nandania, Sabine U. Vorrink, Vidya Velagapudi, Volker M. Lauschke, Olof Beck, Staffan Schmidt, Shahid Ullah, Magnus Ingelman-Sundberg
Publikováno v:
The FASEB Journal
Adverse reactions or lack of response to medications are important concerns for drug development programs. However, faithful predictions of drug metabolism and toxicity are difficult because animal models show only limited translatability to humans.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727a144fba4e4258d14342573a499be7
https://doi.org/10.1096/fj.201601375r
https://doi.org/10.1096/fj.201601375r
Autor:
Eric W, Lumsden, Timothy A, Troppoli, Scott J, Myers, Panos, Zanos, Yasco, Aracava, Jan, Kehr, Jacqueline, Lovett, Sukhan, Kim, Fu-Hua, Wang, Staffan, Schmidt, Carleigh E, Jenne, Peixiong, Yuan, Patrick J, Morris, Craig J, Thomas, Carlos A, Zarate, Ruin, Moaddel, Stephen F, Traynelis, Edna F R, Pereira, Scott M, Thompson, Edson X, Albuquerque, Todd D, Gould
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(11)
Preclinical studies indicate that (2R,6R)-hydroxynorketamine (HNK) is a putative fast-acting antidepressant candidate. Although inhibition of NMDA-type glutamate receptors (NMDARs) is one mechanism proposed to underlie ketamine’s antidepressant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fea4226be62928bc830a4f9eba57b32
https://pubmed.ncbi.nlm.nih.gov/30796190
https://pubmed.ncbi.nlm.nih.gov/30796190
Autor:
Staffan Schmidt, Peter Parker
An increasing interest in commons has generated a rich literature related to co- and participatory design (PD). Besides providing examples, cases and methods, this literature often displays interpretations that are recognisably engaged and political
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38a19649559c62d93c8d59bda643d97
http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-14346
http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-14346
Autor:
Urban Lendahl, Johan Lundkvist, Fredrik Olsson, Shaobo Jin, Susanne Rosqvist, Gerd Multhaup, Staffan Schmidt, Lisa M. Munter, Veit Althoff
Publikováno v:
Journal of Biological Chemistry. 289:1540-1550
Processing of the amyloid precursor protein (APP) by γ-secretase results in generation of Aβ peptides of different lengths ranging from 51 to 30 residues. Accumulation of Aβ and in particular Aβ42 is enhanced by familial Alzheimer disease (FAD) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d615961a595e893366085f768a1fd139
https://doi.org/10.1074/jbc.m113.498246
https://doi.org/10.1074/jbc.m113.498246