Výsledky vyhledávání - "Staerfeldt, Hans Henrik"

Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Autor: Allesøe, Rosa Lundbye, Lundgaard, Agnete Troen, Hernández Medina, Ricardo, Aguayo-Orozco, Alejandro, Johansen, Joachim, Nissen, Jakob Nybo, Brorsson, Caroline, Mazzoni, Gianluca, Niu, Lili, Biel, Jorge Hernansanz, Brasas, Valentas, Webel, Henry, Benros, Michael Eriksen, Pedersen, Anders Gorm, Chmura, Piotr Jaroslaw, Jacobsen, Ulrik Plesner, Mari, Andrea, Koivula, Robert, Mahajan, Anubha, Vinuela, Ana, Tajes, Juan Fernandez, Sharma, Sapna, Haid, Mark, Hong, Mun-Gwan, Musholt, Petra B., de Masi, Federico, Vogt, Josef, Pedersen, Helle Krogh, Gudmundsdottir, Valborg, Jones, Angus, Kennedy, Gwen, Bell, Jimmy, Thomas, E. Louise, Frost, Gary, Thomsen, Henrik, Hansen, Elizaveta, Hansen, Tue Haldor, Vestergaard, Henrik, Muilwijk, Mirthe, Blom, Marieke T., ‘t Hart, Leen M., Pattou, Francois, Raverdy, Violeta, Brage, Soren, Kokkola, Tarja, Heggie, Alison, McEvoy, Donna, Mourby, Miranda, Kaye, Jane, Hattersley, Andrew, McDonald, Timothy, Ridderstråle, Martin, Walker, Mark, Forgie, Ian, Giordano, Giuseppe N., Pavo, Imre, Ruetten, Hartmut, Pedersen, Oluf, Hansen, Torben, Dermitzakis, Emmanouil, Franks, Paul W., Schwenk, Jochen M., Adamski, Jerzy, McCarthy, Mark I., Pearson, Ewan, Banasik, Karina, Rasmussen, Simon, Brunak, S. ren, Froguel, Philippe, Thomas, Cecilia Engel, Haussler, Ragna, Beulens, Joline, Rutters, Femke, Nijpels, Giel, van Oort, Sabine, Groeneveld, Lenka, Elders, Petra, Giorgino, Toni, Rodriquez, Marianne, Nice, Rachel, Perry, Mandy, Bianzano, Susanna, Graefe-Mody, Ulrike, Hennige, Anita, Grempler, Rolf, Baum, Patrick, Stærfeldt, Hans-Henrik, Shah, Nisha, Teare, Harriet, Ehrhardt, Beate, Tillner, Joachim, Dings, Christiane, Lehr, Thorsten, Scherer, Nina, Sihinevich, Iryna, Cabrelli, Louise, Loftus, Heather, Bizzotto, Roberto, Tura, Andrea, Dekkers, Koen, van Leeuwen, Nienke, Groop, Leif, Slieker, Roderick, Ramisch, Anna, Jennison, Christopher, McVittie, Ian, Frau, Francesca, Steckel-Hamann, Birgit, Adragni, Kofi, Thomas, Melissa, Pasdar, Naeimeh Atabaki, Fitipaldi, Hugo, Kurbasic, Azra, Mutie, Pascal, Pomares-Millan, Hugo, Bonnefond, Amelie, Canouil, Mickael, Caiazzo, Robert, Verkindt, Helene, Holl, Reinhard, Kuulasmaa, Teemu, Deshmukh, Harshal, Cederberg, Henna, Laakso, Markku, Vangipurapu, Jagadish, Dale, Matilda, Thorand, Barbara, Nicolay, Claudia, Fritsche, Andreas, Hill, Anita, Hudson, Michelle, Thorne, Claire, Allin, Kristine, Arumugam, Manimozhiyan, Jonsson, Anna, Engelbrechtsen, Line, Forman, Annemette, Dutta, Avirup, Sondertoft, Nadja, Fan, Yong, Gough, Stephen, Robertson, Neil, McRobert, Nicky, Wesolowska-Andersen, Agata, Brown, Andrew, Davtian, David, Dawed, Adem, Donnelly, Louise, Palmer, Colin, White, Margaret, Ferrer, Jorge, Whitcher, Brandon, Artati, Anna, Prehn, Cornelia, Adam, Jonathan, Grallert, Harald, Gupta, Ramneek, Sackett, Peter Wad, Nilsson, Birgitte, Tsirigos, Konstantinos, Eriksen, Rebeca, Jablonka, Bernd, Uhlen, Mathias, Gassenhuber, Johann, Baltauss, Tania, de Preville, Nathalie, Klintenberg, Maria, Abdalla, Moustafa

Publikováno v: Allesøe, R L, Lundgaard, A T, Hernández Medina, R, Aguayo-Orozco, A, Johansen, J, Nissen, J N, Brorsson, C, Mazzoni, G, Niu, L, Biel, J H, Brasas, V, Webel, H, Benros, M E, Pedersen, A G, Chmura, P J, Jacobsen, U P, Mari, A, Koivula, R, Mahajan, A, Vinuela, A, Tajes, J F, Sharma, S, Haid, M, Hong, M-G, Musholt, P B, de Masi, F, Vogt, J, Pedersen, H K, Gudmundsdottir, V, Jones, A, Kennedy, G, Bell, J, Thomas, E L, Frost, G, Thomsen, H, Hansen, E, Hansen, T H, Vestergaard, H, Muilwijk, M, Blom, M T, ‘t Hart, L M, Pattou, F, Raverdy, V, Brage, S, Kokkola, T, Heggie, A, McEvoy, D, Mourby, M, Kaye, J, Hattersley, A, McDonald, T, Ridderstråle, M, Walker, M, Forgie, I, Giordano, G N, Pavo, I, Ruetten, H, Pedersen, O, Hansen, T, Dermitzakis, E, Franks, P W, Schwenk, J M, Adamski, J, McCarthy, M I, Pearson, E, Banasik, K, Rasmussen, S, Brunak, S R, Froguel, P, Thomas, C E, Haussler, R, Beulens, J, Rutters, F, Nijpels, G, van Oort, S, Groeneveld, L, Elders, P, Giorgino, T, Rodriquez, M, Nice, R, Perry, M, Bianzano, S, Graefe-Mody, U, Hennige, A, Grempler, R, Baum, P, Stærfeldt, H-H, Shah, N, Teare, H, Ehrhardt, B, Tillner, J, Dings, C, Lehr, T, Scherer, N, Sihinevich, I, Cabrelli, L, Loftus, H, Bizzotto, R, Tura, A, Dekkers, K, van Leeuwen, N, Groop, L, Slieker, R, Ramisch, A, Jennison, C, McVittie, I, Frau, F, Steckel-Hamann, B, Adragni, K, Thomas, M, Pasdar, N A, Fitipaldi, H, Kurbasic, A, Mutie, P, Pomares-Millan, H, Bonnefond, A, Canouil, M, Caiazzo, R, Verkindt, H, Holl, R, Kuulasmaa, T, Deshmukh, H, Cederberg, H, Laakso, M, Vangipurapu, J, Dale, M, Thorand, B, Nicolay, C, Fritsche, A, Hill, A, Hudson, M, Thorne, C, Allin, K, Arumugam, M, Jonsson, A, Engelbrechtsen, L, Forman, A, Dutta, A, Sondertoft, N, Fan, Y, Gough, S, Robertson, N, McRobert, N, Wesolowska-Andersen, A, Brown, A, Davtian, D, Dawed, A, Donnelly, L, Palmer, C, White, M, Ferrer, J, Whitcher, B, Artati, A, Prehn, C, Adam, J, Grallert, H, Gupta, R, Sackett, P W, Nilsson, B, Tsirigos, K, Eriksen, R, Jablonka, B, Uhlen, M, Gassenhuber, J, IMI DIRECT Consortium, Baltauss, T, de Preville, N, Klintenberg, M & Abdalla, M 2023, ' Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models ', Nature Biotechnology, vol. 41, no. 3, pp. 399-408 . https://doi.org/10.1038/s41587-022-01520-x
Nature Biotechnology, 41(3), 399-408. Nature Publishing Group
Allesøe, R L, Lundgaard, A T, Hernández Medina, R, Aguayo-Orozco, A, Johansen, J, Nissen, J N, Brorsson, C, Mazzoni, G, Niu, L, Biel, J H, Brasas, V, Webel, H, Benros, M E, Pedersen, A G, Chmura, P J, Jacobsen, U P, Mari, A, Koivula, R, Mahajan, A, Vinuela, A, Tajes, J F, Sharma, S, Haid, M, Hong, M G, Musholt, P B, De Masi, F, Vogt, J, Pedersen, H K, Gudmundsdottir, V, Jones, A, Kennedy, G, Bell, J, Thomas, E L, Frost, G, Thomsen, H, Hansen, E, Hansen, T H, Vestergaard, H, Muilwijk, M, Blom, M T, ‘t Hart, L M, Hansen, T, Schwenk, J M, Adamski, J, McCarthy, M I, Pearson, E, Banasik, K, Rasmussen, S, Brunak, S & Franks, P W 2023, ' Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models ', Nature Biotechnology, vol. 41, no. 3, pp. 399-408 . https://doi.org/10.1038/s41587-022-01520-x
Nature Biotechnology, 41, 399-408. NATURE PORTFOLIO
Nature biotechnology, 41(3), 399-408. Nature Publishing Group

The application of multiple omics technologies in biomedical cohorts has the potential to reveal patient-level disease characteristics and individualized response to treatment. However, the scale and heterogeneous nature of multi-modal data makes int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a38183b41c4b550c847aebac0cdbdf
https://research.vumc.nl/en/publications/216574f1-bee3-436a-971a-07c15cf44b94

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Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

Autor: Wilman, Henry R., Parisinos, Constantinos A., Atabaki-Pasdar, Naeimeh, Kelly, Matt, Thomas, E. Louise, Neubauer, Stefan, Jennison, Christopher, Ehrhardt, Beate, Baum, Patrick, Schoelsch, Corinna, Freijer, Jan, Grempler, Rolf, Graefe-Mody, Ulrike, Hennige, Anita, Dings, Christiane, Lehr, Thorsten, Scherer, Nina, Sihinecich, Iryna, Pattou, Francois, Raverdi, Violeta, Caiazzo, Robert, Torres, Fanelly, Verkindt, Helene, Mari, Andrea, Tura, Andrea, Giorgino, Toni, Bizzotto, Froguel, Philippe, Bonneford, Amelie, Canouil, Mickael, Dhennin, Veronique, Brorsson, Caroline, Brunak, Soren, de Masi, Federico, Gudmundsdóttir, Valborg, Pedersen, Helle, Banasik, Karina, Thomas, Cecilia, Sackett, Peter, Staerfeldt, Hans-Henrik, Lundgaard, Agnete, Koopman, Anitra, Rutters, Femke, Beulens, Joline, Groeneveld, Lenka, Thomas, Louise, Whitcher, Brandon, Mahajan, Anubha, Hingorani, Aroon D., Patel, Riyaz S., Hemingway, Harry, Franks, Paul W., Bell, Jimmy D., Banerjee, Rajarshi, Yaghootkar, Hanieh

Publikováno v: Journal of Hepatology, 71(3), 594-602. Elsevier
Wilman, H R, Parisinos, C A, Atabaki-Pasdar, N, Kelly, M, Thomas, E L, Neubauer, S, Jennison, C, Ehrhardt, B, Baum, P, Schoelsch, C, Freijer, J, Grempler, R, Graefe-Mody, U, Hennige, A, Dings, C, Lehr, T, Scherer, N, Sihinecich, I, Pattou, F, Raverdi, V, Caiazzo, R, Torres, F, Verkindt, H, Mari, A, Tura, A, Giorgino, T, Bizzotto, Froguel, P, Bonneford, A, Canouil, M, Dhennin, V, Brorsson, C, Brunak, S, de Masi, F, Gudmundsdóttir, V, Pedersen, H, Banasik, K, Thomas, C, Sackett, P, Staerfeldt, H-H, Lundgaard, A, Koopman, A, Rutters, F, Beulens, J, Groeneveld, L, IMI DIRECT Consortium, Koopman, A, Rutters, F, Beulens, J, Groeneveld, L, Koopman, A, Thomas, L, Whitcher, B, Mahajan, A, Hingorani, A D, Patel, R S, Hemingway, H, Franks, P W, Bell, J D, Banerjee, R & Yaghootkar, H 2019, ' Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration ', Journal of Hepatology, vol. 71, no. 3, pp. 594-602 . https://doi.org/10.1016/j.jhep.2019.05.032

Background & Aims: Excess liver iron content is common and is linked to the risk of hepatic and extrahepatic diseases. We aimed to identify genetic variants influencing liver iron content and use genetics to understand its link to other traits and di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::21d8f03cbd3e4487af956734fab22e15
https://research.vumc.nl/en/publications/07b84fa7-c7f3-4e47-a683-e372d6947099

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