Inflammatory Cytokine Profiles During Exercise in Obese, Diabetic, and Healthy Children

Autor: Shirin Heydari, Pietro Galassetti, Milagros Ibardolaza, Andria M. Pontello, Jaime S. Rosa, Rebecca L. Flores, Stacy R. Oliver

Publikováno v: Journal of Clinical Research in Pediatric Endocrinology
Rosa, Jaime S; Heydari, Shirin; Oliver, Stacy R; Flores, Rebecca L; Pontello, Andria M; Ibardolaza, Milagros; et al.(2011). Inflammatory cytokine profiles during exercise in obese, diabetic, and healthy children.. Journal of clinical research in pediatric endocrinology, 3(3), 115-121. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/15z289nz

Objective: Modulation of inflammatory status is considered a key component of the overall health effects of exercise. This may be especially relevant in children with obesity (Ob) or type 1 diabetes (T1DM), in which an imbalance between pro- and anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88144f66e6eb16e002f75c0494ab411b
http://europepmc.org/articles/PMC3184511

Ex vivoTCR-induced leukocyte gene expression of inflammatory mediators is increased in type 1 diabetic patients but not in overweight children

Autor: Mieko Ogura, Masato Mitsuhashi, Rebecca L. Flores, Jaime S. Rosa, Pietro R. Galassetti, Stacy R. Oliver, Andria M. Pontello

Publikováno v: Diabetes/Metabolism Research and Reviews. 26:33-39

Background Abnormal systemic concentrations of proinflammatory cytokines/chemokines have been implicated in the development of long-term cardiovascular complications in type 1 diabetes (T1DM) and obesity. Whether leukocyte white blood cell (WBC) gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bf8e64b1838aecc3a276ba584f425a
https://doi.org/10.1002/dmrr.1052

Acute Suppression of Circulating sCD40L during Hyperglycemia and Euglycemic-Hyperinsulinemia in Healthy Young Males

Autor: Rebecca L. Flores, Frank Zaldivar, Pietro R. Galassetti, Jaime S. Rosa, Stacy R. Oliver, Andria M. Pontello

Publikováno v: Journal of Investigative Medicine. 56:902-910

sCD40L is a proatherogenic cytokine, part of the tumor necrosis factor (TNF) superfamily and consistently associated with obesity, diabetes, and increased cardiovascular risk. Although the role of sCD40L in the onset/progression of cardiovascular com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c0e0f566e266ba3c80ad0dad427f17
https://doi.org/10.2310/jim.0b013e31818914e4

Altered insulin response to an acute bout of exercise in pediatric obesity

Autor: Diana Vigil, Scott C. Graf, Pietro Galassetti, Brian D. Tran, Szu-Yun Leu, Stacy R. Oliver

Publikováno v: Pediatric exercise science. 26(4)

Pediatric obesity typically induces insulin resistance, often later evolving into type 2 diabetes. While exercise, enhancing insulin sensitivity, is broadly used to prevent this transition, it is unknown whether alterations in the exercise insulin re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0766d400a76c4eb2a96daeb7f4db90f
https://pubmed.ncbi.nlm.nih.gov/24723046

Fasting glucose level modulates cell surface expression of CD11b and CD66b in granulocytes and monocytes of patients with type 2 diabetes

Autor: Peter Horvath, Goutham Ganesan, Frank Zaldivar, Shlomit Radom-Aizik, Stacy R. Oliver, Pietro Galassetti

Publikováno v: Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 61(6)

Introduction Cardiovascular complications are the leading cause of mortality in type 2 diabetes (T2DM), in which onset and progression of atherosclerosis is linked to chronic inflammation. Activation status of innate immune cells (granulocytes [Gc],

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1e69adc17f5c664a799ad09ef1b258
https://pubmed.ncbi.nlm.nih.gov/23686079