Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Stacy L. Mach"'
Autor:
Pasi A. Jänne, David M. Jackman, Paul Kirschmeier, Mohit Butaney, Jason J. Luke, Melissa M. Messineo, Allison O'Connell, Stacy L. Mach, Yanan Kuang, Cloud P. Paweletz, Geoffrey R. Oxnard
PDF file - 71K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745bf69c19c3784a647cbb11f0986d98
https://doi.org/10.1158/1078-0432.22451604.v1
https://doi.org/10.1158/1078-0432.22451604.v1
Autor:
Geoffrey R. Oxnard, Pasi A. Jänne, Lee P. Lim, Jessie M. English, Paul Kirschmeier, Leena Gandhi, Yanan Kuang, Stacy L. Mach, Allison O'Connell, Ryan S. Alden, Chris K. Raymond, Adrian G. Sacher, Cloud P. Paweletz
Supplemental Table 3: Summary of ddPCR and NGS findings. The table shows the tissue genotype, ddPCR results, ddPCR allele frequency (mut / mut +wt allele frequency), NGS mutation calls and allele frequencies, and sequencing reads.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9b818f3ff98931a9b9e55f608c899e
https://doi.org/10.1158/1078-0432.22461074.v1
https://doi.org/10.1158/1078-0432.22461074.v1
Autor:
Geoffrey R. Oxnard, Pasi A. Jänne, Lee P. Lim, Jessie M. English, Paul Kirschmeier, Leena Gandhi, Yanan Kuang, Stacy L. Mach, Allison O'Connell, Ryan S. Alden, Chris K. Raymond, Adrian G. Sacher, Cloud P. Paweletz
Supplemental Table 1: Summary of probe sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9804c74831d64786a614e30df6a1cfe
https://doi.org/10.1158/1078-0432.22461080
https://doi.org/10.1158/1078-0432.22461080
Autor:
Pasi A. Jänne, David M. Jackman, Paul Kirschmeier, Mohit Butaney, Jason J. Luke, Melissa M. Messineo, Allison O'Connell, Stacy L. Mach, Yanan Kuang, Cloud P. Paweletz, Geoffrey R. Oxnard
XLSX file - 25K, cfDNA results for figures 2, 4, 5, calculated both as concentration per mL plasma and as percent mutant.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ed8cfb0b1ad3eb3ccc627c7cb9a384
https://doi.org/10.1158/1078-0432.22451607.v1
https://doi.org/10.1158/1078-0432.22451607.v1
Autor:
Pasi A. Jänne, David M. Jackman, Paul Kirschmeier, Mohit Butaney, Jason J. Luke, Melissa M. Messineo, Allison O'Connell, Stacy L. Mach, Yanan Kuang, Cloud P. Paweletz, Geoffrey R. Oxnard
PDF file - 365K, Supplemental Figure 1: Assay optimization. For each TaqMan probe, the optimal annealing temperature was determined by testing each assay across a temperature gradient of 55.0 - 65{degree sign}C. Typical FAM plots for EGFR L858R (A) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73725199f091d02712e2b455e8d61cda
https://doi.org/10.1158/1078-0432.22451601.v1
https://doi.org/10.1158/1078-0432.22451601.v1
Autor:
Geoffrey R. Oxnard, Pasi A. Jänne, Lee P. Lim, Jessie M. English, Paul Kirschmeier, Leena Gandhi, Yanan Kuang, Stacy L. Mach, Allison O'Connell, Ryan S. Alden, Chris K. Raymond, Adrian G. Sacher, Cloud P. Paweletz
Supplemental Table 2: Compilation of cell line admixture experimental data. The table shows the number of detected mutant reads, the total number of wild-type reads that correspond to the genomic coordinates of the mutant allele, and the frequency of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05d70adbeaca26ea3a17d8525aec2cd
https://doi.org/10.1158/1078-0432.22461077
https://doi.org/10.1158/1078-0432.22461077
Autor:
Pasi A. Jänne, David M. Jackman, Paul Kirschmeier, Mohit Butaney, Jason J. Luke, Melissa M. Messineo, Allison O'Connell, Stacy L. Mach, Yanan Kuang, Cloud P. Paweletz, Geoffrey R. Oxnard
PDF file - 91K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21338d491f7ad3291fb192f3468b15d8
https://doi.org/10.1158/1078-0432.22451598
https://doi.org/10.1158/1078-0432.22451598
Autor:
Pasi A. Jänne, David M. Jackman, Paul Kirschmeier, Mohit Butaney, Jason J. Luke, Melissa M. Messineo, Allison O'Connell, Stacy L. Mach, Yanan Kuang, Cloud P. Paweletz, Geoffrey R. Oxnard
Purpose: Tumor genotyping using cell-free plasma DNA (cfDNA) has the potential to allow noninvasive assessment of tumor biology, yet many existing assays are cumbersome and vulnerable to false-positive results. We sought to determine whether droplet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdec672afc96338c1972a3bf3040d9b9
https://doi.org/10.1158/1078-0432.c.6522228.v1
https://doi.org/10.1158/1078-0432.c.6522228.v1
Autor:
Geoffrey R. Oxnard, Pasi A. Jänne, Lee P. Lim, Jessie M. English, Paul Kirschmeier, Leena Gandhi, Yanan Kuang, Stacy L. Mach, Allison O'Connell, Ryan S. Alden, Chris K. Raymond, Adrian G. Sacher, Cloud P. Paweletz
Supplemental Figure 1: Comparison of targeted sequencing of cfDNA using standard hybridization selection versus Resolution methods. (A) UCSC genome browser depiction of read coverage in the TP53 vicinity. The coverage track representing hybridization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588461d4424c2c91efcca49efa9d431c
https://doi.org/10.1158/1078-0432.22461086
https://doi.org/10.1158/1078-0432.22461086
Autor:
Geoffrey R. Oxnard, Pasi A. Jänne, Lee P. Lim, Jessie M. English, Paul Kirschmeier, Leena Gandhi, Yanan Kuang, Stacy L. Mach, Allison O'Connell, Ryan S. Alden, Chris K. Raymond, Adrian G. Sacher, Cloud P. Paweletz
Purpose: Tumor genotyping is a powerful tool for guiding non–small cell lung cancer (NSCLC) care; however, comprehensive tumor genotyping can be logistically cumbersome. To facilitate genotyping, we developed a next-generation sequencing (NGS) assa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a00e7e1530ccb21ce6193ae4a877249
https://doi.org/10.1158/1078-0432.c.6524693.v1
https://doi.org/10.1158/1078-0432.c.6524693.v1