Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stacy L Musone"'
Autor:
Edward C Hsiao, Yuko Yoshinaga, Trieu D Nguyen, Stacy L Musone, Judy E Kim, Paul Swinton, Isidro Espineda, Carlota Manalac, Pieter J deJong, Bruce R Conklin
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2532 (2008)
Fluorescent reporters are useful for assaying gene expression in living cells and for identifying and isolating pure cell populations from heterogeneous cultures, including embryonic stem (ES) cells. Multiple fluorophores and genetic selection marker
Externí odkaz:
https://doaj.org/article/ee98f97fbb37487691ed66b2f176cc32
Autor:
Lindsey A. Criswell, Pui-Yan Kwok, Ernest T. Lam, Catherine Chu, Stacy L. Musone, Wilson Liao, Joanne Nititham, Kimberly E. Taylor, Annie Poon, Averil Ma
Publikováno v:
Genes & Immunity. 12:176-182
The TNFAIP3 locus at 6q23, encoding A20, has been associated with multiple autoimmune diseases (AIDs). Here, we sequence the coding portions of the gene in order to identify contributing causal polymorphisms that may explain some of the observed asso
Autor:
Ludmila Pawlikowska, Eric Vittinghoff, Pui-Yan Kwok, Zian H. Tseng, Dean Whiteman, Stacy L. Musone, Jeffrey E. Olgin, Feng Lin, Bradley E. Aouizerat
Publikováno v:
Heart Rhythm. 6:1745-1750
Background Transforming growth factor s (TGFs) signaling has been shown to promote myocardial fibrosis and remodeling with coronary artery disease (CAD), and previous studies show a major role for fibrosis in the initiation of malignant ventricular a
Autor:
Stacy L. Musone, Christopher Newton-Cheh, Gary F. Mitchell, Emelia J. Benjamin, Michelle J. Keyes, Joel N. Hirschhorn, Chao-Yu Guo, Joseph A. Vita, Jared A. Drake, Sekar Kathiresan, Christopher J. O'Donnell, Ramachandran S. Vasan, Martin G. Larson, Mitul Vyas, Amy L. Camargo, Daniel Levy
Publikováno v:
Hypertension. 49:1285-1290
Arterial stiffness is a moderately heritable trait that is affected by alterations in the bioavailability of NO. Previous studies have found associations between variants in the gene for endothelial NO synthase ( NOS3 ) and arterial properties. We pr
Autor:
Chao-Yu Guo, Joel N. Hirschhorn, Stacy L. Musone, Sekar Kathiresan, Jared A. Drake, Ramachandran S. Vasan, Christopher Newton-Cheh, Philimon Gona, Christopher J. O'Donnell, Martin G. Larson, Daniel Levy, Thomas J. Wang, Amy L. Camargo, Emelia J. Benjamin
Publikováno v:
Hypertension. 49:846-856
Aldosterone:renin ratio (ARR) is used to screen for hyperaldosteronism. Data regarding correlates of ambulatory ARR in the community and its relation to hypertension incidence are limited. We defined clinical correlates of ARR, determined its heritab
Autor:
Joel N. Hirschhorn, Christopher J. O'Donnell, Peter W.F. Wilson, Emelia J. Benjamin, Philimon Gona, Stacy L. Musone, Amy L. Camargo, Jared A. Drake, Martin G. Larson, John F. Keaney, Sekar Kathiresan, Ramachandran S. Vasan, Daniel Levy, Chao-Yu Guo, Christopher Newton-Cheh
Publikováno v:
Circulation. 113:1415-1423
Background— Serum C-reactive protein (CRP) level is a heritable complex trait that predicts incident cardiovascular disease. We investigated the clinical and genetic sources of interindividual variability in serum CRP. Methods and Results— We stu
Autor:
Timothy W. Behrens, Pui-Yan Kwok, Nataliya Shifrin, Michael F. Seldin, Susan Manzi, Peter K. Gregersen, Michelle Petri, M. Ilyas Kamboh, Kimberly E. Taylor, Joanne Nititham, Lindsey A. Criswell, Ward Ortmann, Stacy L. Musone, Ricardo C. Ferreira, Timothy T. Lu, Averil Ma
Publikováno v:
Nature genetics. 40(9)
The TNFAIP3 (tumor necrosis factor alpha-induced protein 3) gene encodes a ubiquitin editing enzyme, A20, that restricts NF-kappaB-dependent signaling and prevents inflammation. We show that three independent SNPs in the TNFAIP3 region (rs13192841, r
Autor:
Per Egil Hesla, Thomas Meitinger, Marie Dobrovolna, Sheng Seung-Chul Hong, Pui-Yan Kwok, Birgit Frauscher, William T. Longstreth, Juliane Winkelmann, Alex Desautels, Juliette Faraco, Minae Kawashima, Stacy L. Musone, Mark N. Kvale, Guy A. Rouleau, David Kemlink, Jong-Hyun Jeong, Taku Miyagawa, Makoto Honda, Sung-Pil Lee, Stephanie Hesselson, Christine Erhardt, Pablo V. Gejman, Neil Risch, Christian Gieger, Justin Chen, Patrice Bourgin, Birgit Högl, Geert Mayer, Sona Nevsimalova, Jubao Duan, Ling Lin, Libor Kolesar, Daniel R. Salomon, Joachim Hallmayer, H-Erich Wichmann, Matthew Akana, Mali Einen, Terry Young, Emmanuel Mignot, Jacques Montplaisir, Katsushi Tokunaga, Gerald T. Nepom, Paul E. Peppard, Giuseppe Plazzi, Francesca Poli, Yutaka Honda, Douglas F. Levinson, Thanh G.N. Ton
Publikováno v:
Nature genetics
Narcolepsy with cataplexy, characterized by sleepiness and rapid onset into REM sleep, affects 1 in 2,000 individuals. Narcolepsy was first shown to be tightly associated with HLA-DR2 (ref. 3) and later sublocalized to DQB1*0602 (ref. 4). Following s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803b18bb98118d2bd1992fcc82ffbdca
http://hdl.handle.net/11585/76156
http://hdl.handle.net/11585/76156
Autor:
Edward C. Hsiao, Carlota Manalac, Stacy L. Musone, Pieter J. deJong, Yuko Yoshinaga, Isidro Espineda, Bruce R. Conklin, Paul Swinton, Judy E. Kim, Trieu Nguyen
Publikováno v:
Hsiao, EC; Yoshinaga, Y; Nguyen, TD; Musone, SL; Kim, JE; Swinton, P; et al.(2008). Marking embryonic stem cells with a 2A self-cleaving peptide: A NKX2-5 emerald GFP BAC reporter. PLoS ONE, 3(7). doi: 10.1371/journal.pone.0002532. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0pj9z2vq
PloS one, vol 3, iss 7
PLoS ONE, Vol 3, Iss 7, p e2532 (2008)
PLoS ONE
PloS one, vol 3, iss 7
PLoS ONE, Vol 3, Iss 7, p e2532 (2008)
PLoS ONE
Background: Fluorescent reporters are useful for assaying gene expression in living cells and for identifying and isolating pure cell populations from heterogeneous cultures, including embryonic stem (ES) cells. Multiple fluorophores and genetic sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b7b0b0cfd3aec26ea7b2e58f4001e1
http://www.escholarship.org/uc/item/0pj9z2vq
http://www.escholarship.org/uc/item/0pj9z2vq
Autor:
Chao-Yu Guo, Ralph B. D'Agostino, Stacy L. Musone, Christopher Newton-Cheh, Jared A. Drake, Aarti Surti, Christopher J. O'Donnell, Amy L. Camargo, Daniel Levy, Joel N. Hirschhorn, Martin G. Larson, Emelia J. Benjamin
Publikováno v:
Circulation. 116(10)
Background— QT prolongation is associated with increased risk of sudden cardiac death in the general population and in people exposed to QT-prolonging drugs. Mutations in the KCNH2 gene encoding the HERG potassium channel cause 30% of long-QT syndr