Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stacy E. Dixon"'
Autor:
Jiachen Wang, Stacy E Dixon, Li-Min Ting, Ting-Kai Liu, Victoria Jeffers, Matthew M Croken, Myrasol Calloway, Dominique Cannella, Mohamed Ali Hakimi, Kami Kim, William J Sullivan
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003830 (2014)
Histone acetylation has been linked to developmental changes in gene expression and is a validated drug target of apicomplexan parasites, but little is known about the roles of individual histone modifying enzymes and how they are recruited to target
Externí odkaz:
https://doaj.org/article/f1ae95746a6f44ef882a37a662a2b130
Autor:
William J. Sullivan, Kami Kim, Myrasol Calloway, Li Min Ting, Victoria Jeffers, Dominique Cannella, Ting-Kai Liu, Stacy E. Dixon, Jiachen Wang, Mohamed-Ali Hakimi, Matthew M. Croken
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003830 (2014)
PLoS Pathogens
PLoS Pathogens
Histone acetylation has been linked to developmental changes in gene expression and is a validated drug target of apicomplexan parasites, but little is known about the roles of individual histone modifying enzymes and how they are recruited to target
Publikováno v:
Molecular and biochemical parasitology. 175(2)
We have previously shown that protozoan parasites, such as Toxoplasma gondii, contain a high prevalence of intrinsically disordered regions in their predicted proteins. Here, we determine that both TgGCN5-family histone acetyltransferases (HATs) cont
The opportunistic apicomplexan parasiteToxoplasma gondiidamages fetuses in utero and threatens immunocompromised individuals. The toxicity associated with standard antitoxoplasmal therapies, which target the folate pathway, underscores the importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0538eef5653db1c2a702e7648a3608
https://europepmc.org/articles/PMC1140536/
https://europepmc.org/articles/PMC1140536/