Výsledky vyhledávání - "Stacy A. Genagon"

A killed, genetically engineered derivative of a wild-type extraintestinal pathogenic E. coli strain is a vaccine candidate

Autor: Thomas A. Russo, Ruth Olson, Brian D. Johnston, Janet M. Beanan, Stacy A. Genagon, Bruce A. Davidson, James R. Johnson, Ulrike MacDonald, John J. Cope

Publikováno v: Vaccine. 25:3859-3870

Infections due to extraintestinal pathogenic E. coli (ExPEC) result in significant morbidity, mortality and increased healthcare costs. An efficacious vaccine against ExPEC would be desirable. In this report, we explore the use of killed-whole E. col

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07526b36002387f37edc9bed409d02d9
https://doi.org/10.1016/j.vaccine.2007.01.100

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E. colivirulence factor hemolysin induces neutrophil apoptosis and necrosis/lysis in vitro and necrosis/lysis and lung injury in a rat pneumonia model

Autor: Ruth Olson, Janet M. Beanan, Stacy A. Genagon, Patrick D. Pawlicki, Bruce A. Holm, Ulrike MacDonald, Paul R. Knight, Bruce A. Davidson, Natalie M. Warholic, Thomas A. Russo

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 289:L207-L216

Enteric gram-negative bacilli, such as Escherichia coli are the most common cause of nosocomial pneumonia. In this study a wild-type extraintestinal pathogenic strain of E. coli (ExPEC)(CP9) and isogenic derivatives deficient in hemolysin (Hly) and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa662d9f981aa4d2061f4c08f1e439ed
https://doi.org/10.1152/ajplung.00482.2004

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Surfactant dysfunction and lung injury due to the E. coli virulence factor hemolysin in a rat pneumonia model

Autor: Ruth Olson, Bruce A. Holm, Janet M. Beanan, rd Paul R. Knight, Robert H. Notter, Stacy A. Genagon, Thomas A. Russo, Patricia R. Chess, Bruce A. Davidson, Zhengdong Wang

Publikováno v: American journal of physiology. Lung cellular and molecular physiology. 292(3)

This study tests the hypothesis that the virulence factor hemolysin (Hly) expressed by extraintestinal pathogenic Escherichia coli contributes to surfactant dysfunction and lung injury in a rat model of gram-negative pneumonia. Rats were instilled in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4a18e28f797dd37ddb67e8ffcf7b44
https://pubmed.ncbi.nlm.nih.gov/17341765

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Extraintestinal Pathogenic Escherichia coli Survives within Neutrophils▿

Autor: Stacy A. Genagon, Helen Nazareth, Thomas A. Russo

Extracellular pathogenic Escherichia coli (ExPEC) strains are common causes of a variety of clinical syndromes, including urinary tract infections, abdominal infections, nosocomial pneumonia, neonatal meningitis, and sepsis. ExPEC strains are extrace

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fa6afa6c1b6f9e56c244a0608abc17
https://europepmc.org/articles/PMC1932911/

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