Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Stacy A, Malaker"'
Autor:
Joann Chongsaritsinsuk, Alexandra D. Steigmeyer, Keira E. Mahoney, Mia A. Rosenfeld, Taryn M. Lucas, Courtney M. Smith, Alice Li, Deniz Ince, Fiona L. Kearns, Alexandria S. Battison, Marie A. Hollenhorst, D. Judy Shon, Katherine H. Tiemeyer, Victor Attah, Catherine Kwon, Carolyn R. Bertozzi, Michael J. Ferracane, Mark A. Lemmon, Rommie E. Amaro, Stacy A. Malaker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Mucin-domain glycoproteins are densely O-glycosylated and play critical roles in a host of biological functions. In particular, the T cell immunoglobulin and mucin-domain containing family of proteins (TIM-1, -3, -4) decorate immune cells an
Externí odkaz:
https://doaj.org/article/c4f9c600267c4d6cb125292d69f93726
Autor:
Valentina Rangel-Angarita, Keira E. Mahoney, Catherine Kwon, Raibat Sarker, Taryn M. Lucas, Stacy A. Malaker
Publikováno v:
JACS Au, Vol 3, Iss 9, Pp 2498-2509 (2023)
Externí odkaz:
https://doaj.org/article/f34729a7c0344005bae795d9356a9317
Autor:
Xin Huang, Thomas Nero, Ranjuna Weerasekera, Katherine H. Matej, Alex Hinbest, Zhaowei Jiang, Rebecca F. Lee, Longjun Wu, Cecilia Chak, Japinder Nijjer, Isabella Gibaldi, Hang Yang, Nathan Gamble, Wai-Leung Ng, Stacy A. Malaker, Kaelyn Sumigray, Rich Olson, Jing Yan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Bacterial biofilms are formed on environmental surfaces and host tissues, and facilitate host colonization and antibiotic resistance by human pathogens. Bacteria often express multiple adhesive proteins (adhesins), but it is often unclear wh
Externí odkaz:
https://doaj.org/article/7b2ea6190c6c4c4d9137608f2090ff78
Autor:
Anna Cioce, Beatriz Calle, Tatiana Rizou, Sarah C. Lowery, Victoria L. Bridgeman, Keira E. Mahoney, Andrea Marchesi, Ganka Bineva-Todd, Helen Flynn, Zhen Li, Omur Y. Tastan, Chloe Roustan, Pablo Soro-Barrio, Mahmoud-Reza Rafiee, Acely Garza-Garcia, Aristotelis Antonopoulos, Thomas M. Wood, Tessa Keenan, Peter Both, Kun Huang, Fabio Parmeggian, Ambrosius P. Snijders, Mark Skehel, Svend Kjær, Martin A. Fascione, Carolyn R. Bertozzi, Stuart M. Haslam, Sabine L. Flitsch, Stacy A. Malaker, Ilaria Malanchi, Benjamin Schumann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Changes in glycoprotein expression are correlates of disease, but secreted glycoproteins cannot be accurately traced to their cell line of origin. Here, the authors develop a strategy to chemically tag and profile glycoproteins in a cell line-specifi
Externí odkaz:
https://doaj.org/article/32c82b244eab4f4ebf7b10a1ff93a4d5
Autor:
Stacy A. Malaker, Nicholas M. Riley, D. Judy Shon, Kayvon Pedram, Venkatesh Krishnan, Oliver Dorigo, Carolyn R. Bertozzi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Mucin-domain glycoproteins are densely O-glycosylated proteins with unique secondary structure that imparts a large influence on cellular environments. Here, the authors develop a technique to selectively enrich and characterize mucin-domain glycopro
Externí odkaz:
https://doaj.org/article/011718bd9681426e8bb6f573bfbb80d9
Autor:
Beatriz Calle, Edgar Gonzalez-Rodriguez, Keira E. Mahoney, Anna Cioce, Ganka Bineva-Todd, Omur Y. Tastan, Chloe Roustan, Helen Flynn, Stacy A. Malaker, Benjamin Schumann
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101974- (2023)
Summary: Despite the known disease relevance of glycans, the biological function and substrate specificities of individual glycosyltransferases are often ill-defined. Here, we describe a protocol to develop chemical, bioorthogonal reporters for the a
Externí odkaz:
https://doaj.org/article/4564c10ac92e47fcb3259675164a5533
Autor:
Neil G. Rumachik, Stacy A. Malaker, Nicole Poweleit, Lucy H. Maynard, Christopher M. Adams, Ryan D. Leib, Giana Cirolia, Dennis Thomas, Susan Stamnes, Kathleen Holt, Patrick Sinn, Andrew P. May, Nicole K. Paulk
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 98-118 (2020)
Different approaches are used in the production of recombinant adeno-associated virus (rAAV). The two leading approaches are transiently transfected human HEK293 cells and live baculovirus infection of Spodoptera frugiperda (Sf9) insect cells. Unexpl
Externí odkaz:
https://doaj.org/article/5bf725043a6b4f7f9442d02c1d0f7c87
Autor:
Sarah A. Penny, Jennifer G. Abelin, Stacy A. Malaker, Paisley T. Myers, Abu Z. Saeed, Lora G. Steadman, Dina L. Bai, Stephen T. Ward, Jeffrey Shabanowitz, Donald F. Hunt, Mark Cobbold
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
There is a pressing need for novel immunotherapeutic targets in colorectal cancer (CRC). Cytotoxic T cell infiltration is well established as a key prognostic indicator in CRC, and it is known that these tumor infiltrating lymphocytes (TILs) target a
Externí odkaz:
https://doaj.org/article/c061e36b679342809afb621a520a51ca
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Progress in recombinant AAV gene therapy product and process development has advanced our understanding of the basic biology of this critical delivery vector. The discovery of rAAV capsid post-translational modifications (PTMs) has spurred interest i
Externí odkaz:
https://doaj.org/article/6b97b356396c4be885faf58cabe4ca20
Publikováno v:
Glycobiology. 33:178-181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bd566ba169fabc756a0bb0e9add5df0
https://doi.org/10.1093/glycob/cwad016
https://doi.org/10.1093/glycob/cwad016