Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stacy Crumley"'
Autor:
Michael R, Erdos, Wayne A, Cabral, Urraca L, Tavarez, Kan, Cao, Jelena, Gvozdenovic-Jeremic, Narisu, Narisu, Patricia M, Zerfas, Stacy, Crumley, Yoseph, Boku, Gunnar, Hanson, Dan V, Mourich, Ryszard, Kole, Michael A, Eckhaus, Leslie B, Gordon, Francis S, Collins
Publikováno v:
Nature medicine. 27(3)
Hutchinson-Gilford progeria syndrome (HGPS) is a rare accelerated aging disorder characterized by premature death from myocardial infarction or stroke. It is caused by de novo single-nucleotide mutations in the LMNA gene that activate a cryptic splic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0400692d97ac2b90113adb4ea030b808
https://pubmed.ncbi.nlm.nih.gov/33772219
https://pubmed.ncbi.nlm.nih.gov/33772219
Publikováno v:
PLoS Pathogens, Vol 8, Iss 12, p e1003073 (2012)
The viral family Arenaviridae includes a number of viruses that can cause hemorrhagic fever in humans. Arenavirus infection often involves multiple organs and can lead to capillary instability, impaired hemostasis, and death. Preclinical testing for
Externí odkaz:
https://doaj.org/article/a0fbd6ecf3484caa8908e1d864f4d86b
Autor:
Travis K. Warren, Dana L. Swenson, Nicole L. Garza, Jay Wells, Dan V. Mourich, Lian Dong, Kelly L. Warfield, Kelly S Donner, Donald K. Nichols, Patrick L. Iversen, Stacy Crumley, Sina Bavari, Sean A. Van Tongeren
Publikováno v:
Nature Medicine. 16:991-994
Currently, no vaccines or therapeutics are licensed to counter Ebola or Marburg viruses, highly pathogenic filoviruses that are causative agents of viral hemorrhagic fever. Here we show that administration of positively charged phosphorodiamidate mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130620075065a36d1890d9269df5c33f
https://doi.org/10.1038/nm.2202
https://doi.org/10.1038/nm.2202
Autor:
Stacy Crumley, Claire Y.-H. Huang, Shawn J. Silengo, Patrick L. Iversen, Robert E. Blouch, Adams Amantana, David A. Stein, Richard M. Kinney
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives: To determine the antiviral activity of phosphorodiamidate morpholino oligomers (PMO) and peptide-conjugated PMO (PPMO) in AG129 mice infected with dengue 2 virus (DENV-2). Methods: Antisense PMO and PPMO were designed against the 5 0 term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50d25e12821b0f21e6281bf3bc1d610
http://europepmc.org/articles/PMC7109848
http://europepmc.org/articles/PMC7109848
Autor:
Nikki B. Marshall, Laura L. Hauck, Dave J Hinrichs, Dan V. Mourich, Patrick L. Iversen, Stacy Crumley, Shannon K. Oda, Carla A Moentenich, Frederick J. Schnell
Publikováno v:
Nucleic acid therapeutics. 24(2)
Activated and regulatory T cells express the negative co-stimulatory molecule cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) that binds B7 on antigen-presenting cells to mediate cellular responses. Single nucleotide polymorphisms in the CTLA-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1cc1652646cc4cf47bd5620cd9fd50
https://pubmed.ncbi.nlm.nih.gov/24494586
https://pubmed.ncbi.nlm.nih.gov/24494586
Publikováno v:
The Journal of Immunology. 186:65.44-65.44
Phosphorodiamidate morpholino oligomers (PMOs) are neutrally charged antisense agents that interfere with target gene expression by inhibition of translation or by altering splicing of pre-mRNA. PMOs have been shown to be highly specific and potent t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2d5e1c7856f6b3fb8d9417bc0609cc2
https://doi.org/10.4049/jimmunol.186.supp.65.44
https://doi.org/10.4049/jimmunol.186.supp.65.44
Autor:
David A. Stein, Claire Y.-H. Huang, Shawn Silengo, Adams Amantana, Stacy Crumley, Robert E. Blouch, Patrick L. Iversen, Richard M. Kinney, Stein, David A, Huang, Claire Y-H, Silengo, Shawn, Amantana, Adams, Crumley, Stacy, Blouch, Robert E, Iversen, Patrick L, Kinney, Richard M
Publikováno v:
Journal of Antimicrobial Chemotherapy (JAC); Sep2008, Vol. 62 Issue 3, p555-555, 1p