Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stacy, Kentner"'
Autor:
Robert W Wilkinson, Hormas Ghadially, Stacy Kentner, Suzanne Isabelle Sitnikova, Sophie Munnings-Tomes, Elena Galvani, Kathy Mulgrew, Chris Rands, Judit España Agustí, Tianhui Zhang, Kristina M Ilieva, Guglielmo Rosignoli, Matthew J Robinson, Tim Slidel, Simon J Dovedi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Immuno-oncology therapies are now part of the standard of care for cancer in many indications. However, durable objective responses remain limited to a subset of patients. As such, there is a critical need to identify biomarkers that can p
Externí odkaz:
https://doaj.org/article/0daba65ab2174eb2906d5b3b2486abf0
Autor:
Michael Overstreet, Vanessa Muniz-Medina, Ruoyan Chen, James Kurasawa, Stacy Kentner, Deepali Malhotra, Jane Osbourn, Jill Walker
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/75cbb845e8ff4749aec5d327a3c881a3
Autor:
Scott A. Hammond, Andrew Weinberg, Nicholas P. Morris, Louis Picker, Michael K. Axthelm, Andrew Sylwester, Haesun Park, Andrew J. Pierce, Lolke de Haan, Nicholas Buss, Steven Eck, Hui Feng, Melissa Damschroder, Qun Du, Shino Hanabuchi, James Hair, Kelly McGlinchey, Kathy Mulgrew, Stacy Kentner, Chad Morris, Catherine Augé, Michael D. Oberst
Expression of cell surface Fc gamma receptors on human cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123f7d8216dfd0b1f3ce6f1f64cd89ab
https://doi.org/10.1158/1535-7163.22505539.v1
https://doi.org/10.1158/1535-7163.22505539.v1
Autor:
Yariv Mazor, Robert W. Wilkinson, Daniel J. Freeman, Ikbel Achour, William Dall'Acqua, Aleksandra D. Toloczko, Thomas V. Murray, Frances Neal, Gareth J. Browne, Godfrey J. Rainey, Michelle Morrow, Asis Palazon, Yanli Wu, James Dodgson, Michael G. Overstreet, Yaya Wang, Kathy Mulgrew, Stacy Kentner, Xiaofang Jin, Arthur Lewis, Kapil Vashisht, Shelby D. Gainer, Deepa S. Subramaniam, Ben Tran, Seock-Ah Im, Bo Wang, Sumati Hasani, Des C. Jones, James Hair, Anna Hansen, Lorraine Irving, Suzanne I. Sitnikova, Chunning Yang, Matthew J. Elder, Simon J. Dovedi
Supplementary Materials and Methods, and Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238b4ab5c831dd6063dffdf564c8ad3c
https://doi.org/10.1158/2159-8290.22540037
https://doi.org/10.1158/2159-8290.22540037
Autor:
Scott A. Hammond, Andrew Weinberg, Nicholas P. Morris, Louis Picker, Michael K. Axthelm, Andrew Sylwester, Haesun Park, Andrew J. Pierce, Lolke de Haan, Nicholas Buss, Steven Eck, Hui Feng, Melissa Damschroder, Qun Du, Shino Hanabuchi, James Hair, Kelly McGlinchey, Kathy Mulgrew, Stacy Kentner, Chad Morris, Catherine Augé, Michael D. Oberst
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae534900ee576be4839bebdf0965290a
https://doi.org/10.1158/1535-7163.22505521
https://doi.org/10.1158/1535-7163.22505521
Autor:
Scott A. Hammond, Andrew Weinberg, Nicholas P. Morris, Louis Picker, Michael K. Axthelm, Andrew Sylwester, Haesun Park, Andrew J. Pierce, Lolke de Haan, Nicholas Buss, Steven Eck, Hui Feng, Melissa Damschroder, Qun Du, Shino Hanabuchi, James Hair, Kelly McGlinchey, Kathy Mulgrew, Stacy Kentner, Chad Morris, Catherine Augé, Michael D. Oberst
Ligation of OX40 (CD134, TNFRSF4) on activated T cells by its natural ligand (OX40L, CD252, TNFSF4) enhances cellular survival, proliferation, and effector functions such as cytokine release and cellular cytotoxicity. We engineered a recombinant huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9055300403acf6ff9ac96ec905dac3f
https://doi.org/10.1158/1535-7163.c.6538102.v1
https://doi.org/10.1158/1535-7163.c.6538102.v1
Autor:
Yariv Mazor, Robert W. Wilkinson, Daniel J. Freeman, Ikbel Achour, William Dall'Acqua, Aleksandra D. Toloczko, Thomas V. Murray, Frances Neal, Gareth J. Browne, Godfrey J. Rainey, Michelle Morrow, Asis Palazon, Yanli Wu, James Dodgson, Michael G. Overstreet, Yaya Wang, Kathy Mulgrew, Stacy Kentner, Xiaofang Jin, Arthur Lewis, Kapil Vashisht, Shelby D. Gainer, Deepa S. Subramaniam, Ben Tran, Seock-Ah Im, Bo Wang, Sumati Hasani, Des C. Jones, James Hair, Anna Hansen, Lorraine Irving, Suzanne I. Sitnikova, Chunning Yang, Matthew J. Elder, Simon J. Dovedi
The clinical benefit of PD-1 blockade can be improved by combination with CTLA4 inhibition but is commensurate with significant immune-related adverse events suboptimally limiting the doses of anti-CTLA4 mAb that can be used. MEDI5752 is a monovalent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca7eaed273b219faf1bb63ec9cf8694
https://doi.org/10.1158/2159-8290.c.6549263
https://doi.org/10.1158/2159-8290.c.6549263
Autor:
Scott A. Hammond, Andrew Weinberg, Nicholas P. Morris, Louis Picker, Michael K. Axthelm, Andrew Sylwester, Haesun Park, Andrew J. Pierce, Lolke de Haan, Nicholas Buss, Steven Eck, Hui Feng, Melissa Damschroder, Qun Du, Shino Hanabuchi, James Hair, Kelly McGlinchey, Kathy Mulgrew, Stacy Kentner, Chad Morris, Catherine Augé, Michael D. Oberst
Supplementary Figure 5. Lack of NK cell mediated ADCC and complement protein C1q binding by MEDI6383. Supplementary Figure 6. MEDI6383 mediated release of cytokines from primary human T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db041ff2d652c7052f608239ed819b86
https://doi.org/10.1158/1535-7163.22505527.v1
https://doi.org/10.1158/1535-7163.22505527.v1
Autor:
Bo Wang, Frances Neal, Arthur Lewis, Kapil Vashisht, Deepa S. Subramaniam, Des C. Jones, Sumati Hasani, Daniel J. Freeman, Chunning Yang, Lorraine Irving, Michael G. Overstreet, Gareth J. Browne, Suzanne I. Sitnikova, James Hair, Robert W. Wilkinson, Yaya Wang, Ben Tran, Ikbel Achour, James Dodgson, Shelby D. Gainer, Xiaofang Jin, Seock-Ah Im, William F Dall'Acqua, Yariv Mazor, Godfrey Rainey, Asis Palazon, Anna Hansen, Yanli Wu, Matthew J. Elder, Stacy Kentner, Aleksandra D. Toloczko, Michelle Morrow, Murray Thomas Vincent, Simon J. Dovedi, Kathy Mulgrew
Publikováno v:
Cancer Discovery. 11:1100-1117
The clinical benefit of PD-1 blockade can be improved by combination with CTLA4 inhibition but is commensurate with significant immune-related adverse events suboptimally limiting the doses of anti-CTLA4 mAb that can be used. MEDI5752 is a monovalent
Autor:
Deepali Malhotra, Jill Walker, Ruoyan Chen, Jane K. Osbourn, Vanessa Muniz-Medina, James Kurasawa, Stacy Kentner, Gordon Moody, Michael G. Overstreet
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background With the success of T cell checkpoint antagonists in treating cancer, we must better understand treatment response heterogeneity and develop more physiological preclinical models for evaluating the next wave of candidate therapeutics. Seve