Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Stacie L. Lambert"'
Autor:
John Powderly, Alexander Spira, Shunsuke Kondo, Toshihiko Doi, Jason J. Luke, Drew Rasco, Bo Gao, Minna Tanner, Philippe A. Cassier, Anas Gazzah, Antoine Italiano, Diego Tosi, Daniel E. Afar, Apurvasena Parikh, Benjamin Engelhardt, Stefan Englert, Stacie L. Lambert, Sreeneeranj Kasichayanula, Sven Mensing, Rajeev Menon, Gregory Vosganian, Anthony Tolcher
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 277-287 (2021)
Budigalimab is a humanized, recombinant, Fc mutated IgG1 monoclonal antibody targeting programmed cell death 1 (PD‐1) receptor, currently in phase I clinical trials. The safety, efficacy, pharmacokinetics (PKs), pharmacodynamics (PDs), and budigali
Externí odkaz:
https://doaj.org/article/2e9537a22ea94fefa65b2b3c6cd4e048
Autor:
Christine M. D. Lingblom, Sangeeta Kowli, Nithya Swaminathan, Holden T. Maecker, Stacie L. Lambert
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background Mass cytometry, or CyTOF (Cytometry by Time-of-Flight), permits the simultaneous detection of over 40 phenotypic and functional immune markers in individual cells without the issues of spectral overlap seen in traditional flow cyt
Externí odkaz:
https://doaj.org/article/d280389052384ae6b9baaf4c47b2cc5e
Autor:
Adriana Weinberg, Stacie L Lambert, Jennifer Canniff, Li Yu, Nancy Lang, Mark T Esser, Judith Falloon, Myron J Levin
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 10, Pp 2466-2474 (2019)
Background: Infections with respiratory syncytial virus (RSV) cause significant morbidity and hospitalization in older adults. We studied the humoral, mucosal and B cell responses of an investigational adjuvanted RSV sF vaccine, MEDI7510, in older ad
Externí odkaz:
https://doaj.org/article/8ee7ccb20b7f42a1b450016580d134ea
Autor:
Myron J. Levin, Nancy Lang, Mark T. Esser, Li Yu, Judith Falloon, Jennifer Canniff, Adriana Weinberg, Stacie L. Lambert
Publikováno v:
Hum Vaccin Immunother
Background: Infections with respiratory syncytial virus (RSV) cause significant morbidity and hospitalization in older adults. We studied the humoral, mucosal and B cell responses of an investigational adjuvanted RSV sF vaccine, MEDI7510, in older ad
Autor:
Stacie L. Lambert, Chun Zhang, Claire Guo, Tolga Turan, David L. Masica, Stefan Englert, Yuni Fang, James Sheridan, Robert Tyler McLaughlin, Catherine Tribouley, Greg Vosganian, Daniel Afar
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 45(3)
Budigalimab, a novel anti-PD-1 monoclonal antibody, demonstrated efficacy and biomarker pharmacodynamics in patients with head and neck squamous cell carcinoma (HNSCC) or non-small cell lung cancer (NSCLC) consistent with those reported by other PD-1
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42610 (2012)
The B lymphotrophic γ-herpesvirus EBV is associated with a variety of lymphoid- and epithelial-derived malignancies, including B cell lymphomas in immunocompromised and immunosuppressed individuals. The primary oncogene of EBV, latent membrane prote
Externí odkaz:
https://doaj.org/article/557fdb401cf44e1a8b6baadb417bcf34
Autor:
Nga Nguyen, Floro Cataniag, Michael P. McCarthy, Zhaoti Wang, Greg Duke, Stacie L. Lambert, Alivelu Irrinki, Yi Liu, A. Louise McCormick, Hui Liu, Kirsten Schneider-Ohrum, Shahin Aslam, Corinne Cayatte
Publikováno v:
Journal of Virology. 90:10133-10144
With the goal of developing a virus-like particle-based vaccine based on dense bodies (DB) produced by human cytomegalovirus (HCMV) infections, we evaluated scalable culture, isolation, and inactivation methods and applied technically advanced assays
Autor:
Holden T. Maecker, Christine M. D. Lingblom, Nithya Swaminathan, Sangeeta Kowli, Stacie L. Lambert
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Background Mass cytometry, or CyTOF (Cytometry by Time-of-Flight), permits the simultaneous detection of over 40 phenotypic and functional immune markers in individual cells without the issues of spectral overlap seen in traditional flow cytometry. M
Autor:
Mark T. Esser, Jared Pache, Li Yu, Stacie L. Lambert, Cindy Shambaugh, Sarieh Azshirvani, Fengrong Zuo
Publikováno v:
Clinical and Vaccine Immunology : CVI
Neutralizing antibodies specific for respiratory syncytial virus (RSV) represent a major protective mechanism against RSV infection, as demonstrated by the efficacy of the immune-prophylactic monoclonal antibody palivizumab in preventing RSV-associat
Autor:
John Ervin, Tonya Villafana, Therese Takas, Li Yu, Judith Falloon, Diane Krieger, Jing Yu, Filip Dubovsky, H. Keipp Talbot, Stacie L. Lambert, Craig Curtis, Mark T. Esser
Publikováno v:
Clinical and Vaccine Immunology : CVI
This is the second phase 1 study of a respiratory syncytial virus (RSV) vaccine containing RSV fusion protein (sF) adjuvanted with glucopyranosyl lipid A (GLA) in a squalene-based 2% stable emulsion (GLA-SE). In this randomized, double-blind study, 2