Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Staci M. Rakowiecki"'
Autor:
Hannie Kremer, Kevin K. Ohlemiller, Staci M. Rakowiecki, Christian Gilissen, Jiddeke M. van de Kamp, Erdi Kucuk, Alex M Rohacek, Jeroen Smits, Jaap Oostrik, Amir Nankali, John S. Oghalai, Benjamin L. Prosser, Douglas J. Epstein, Klaus H. Kaestner, Tingfang Chen, Cornelis P. Lanting, Matthew A. Caporizzo, Ronald J.E. Pennings
Publikováno v:
Developmental Cell, 56, 10, pp. 1526-1540.e7
Dev Cell
Developmental Cell, 56, 1526-1540.e7
Chen, T, Rohacek, A M, Caporizzo, M, Nankali, A, Smits, J J, Oostrik, J, Lanting, C P, Kücük, E, Gilissen, C, van de Kamp, J M, Pennings, R J E, Rakowiecki, S M, Kaestner, K H, Ohlemiller, K K, Oghalai, J S, Kremer, H, Prosser, B L & Epstein, D J 2021, ' Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing ', Developmental Cell, vol. 56, no. 10, pp. 1526-1540.e7 . https://doi.org/10.1016/j.devcel.2021.04.017
Developmental Cell, 56(10), 1526-1540.e7. Cell Press
Dev Cell
Developmental Cell, 56, 1526-1540.e7
Chen, T, Rohacek, A M, Caporizzo, M, Nankali, A, Smits, J J, Oostrik, J, Lanting, C P, Kücük, E, Gilissen, C, van de Kamp, J M, Pennings, R J E, Rakowiecki, S M, Kaestner, K H, Ohlemiller, K K, Oghalai, J S, Kremer, H, Prosser, B L & Epstein, D J 2021, ' Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing ', Developmental Cell, vol. 56, no. 10, pp. 1526-1540.e7 . https://doi.org/10.1016/j.devcel.2021.04.017
Developmental Cell, 56(10), 1526-1540.e7. Cell Press
In mammals, sound is detected by mechanosensory hair cells that are activated in response to vibrations at frequency-dependent positions along the cochlear duct. We demonstrate that inner ear supporting cells provide a structural framework for transm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dee4d64f9b711a9482e5c2b2919c854
https://repository.ubn.ru.nl/handle/2066/233882
https://repository.ubn.ru.nl/handle/2066/233882
Autor:
Douglas J. Epstein, Ying-Tao Zhao, James Meyers, Kyoung-Jae Won, Victor Muthu, Shweta Ramdas, Christopher D. Brown, Kevin A. Peterson, Staci M. Rakowiecki, Yao Yao, Alexander S. Brown, Alex M Rohacek
Publikováno v:
Muthu, V, Rohacek, A M, Yao, Y, Rakowiecki, S M, Brown, A S, Zhao, Y-T, Meyers, J, Won, K-J, Ramdas, S, Brown, C D, Peterson, K A & Epstein, D J 2019, ' Genomic architecture of Shh-dependent cochlear morphogenesis ', Development (Cambridge, England), vol. 146, no. 18, 181339 . https://doi.org/10.1242/dev.181339
Development
Development
The mammalian cochlea develops from a ventral outgrowth of the otic vesicle in response to Shh signaling. Mouse embryos lacking Shh or its essential signal transduction components display cochlear agenesis, however, a detailed understanding of the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a12f8d61de574d527ab91a68984a47
https://curis.ku.dk/ws/files/247388696/dev181339.full.pdf
https://curis.ku.dk/ws/files/247388696/dev181339.full.pdf
Publikováno v:
Developmental Biology. 399:177-187
Wnt1 and Wnt3a secreted from the dorsal neural tube were previously shown to regulate a gene expression program in the dorsal otic vesicle that is necessary for vestibular morphogenesis (Riccomagno et al., 2005. Genes Dev. 19, 1612-1623). Unexpectedl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc535acc3bc0456363affa2adb95f06
https://doi.org/10.1016/j.ydbio.2015.01.001
https://doi.org/10.1016/j.ydbio.2015.01.001
Autor:
Gregor Andelfinger, Susan A. Gauthier, Douglas J. Epstein, Anne-Marie Patenaude, Severine Leclerc, Philippe Gros, Elena Torban, Staci M. Rakowiecki
Publikováno v:
Proceedings of the National Academy of Sciences. 105:3449-3454
Neural tube defects (NTDs) are very frequent congenital abnormalities in humans. Recently, we have documented independent association of Vangl1 and Vangl2 gene mutations with NTDs. In the Looptail mouse, homozygosity (but not heterozygosity) for loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5406ab9828993ee9d5d1f10d891f6867
https://doi.org/10.1073/pnas.0712126105
https://doi.org/10.1073/pnas.0712126105
Publikováno v:
Developmental Neuroscience. 28:49-57
Many cells in the mammalian brain undergo apoptosis as a normal and critical part of development but the signals that regulate the survival and death of neural progenitor cells and the neurons they produce are not well understood. The Notch signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dcf46cb0a6a8e1f9dad6b7696c7b95
https://doi.org/10.1159/000090752
https://doi.org/10.1159/000090752
The morphogenetic program that shapes the three semicircular canals (SSCs) must be executed with extreme precision to satisfy their complex vestibular function. The SSCs emerge from epithelial outgrowths of the dorsal otocyst, the central regions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8683b3b37d3f6c8dc43dc3e2da8561b2
https://europepmc.org/articles/PMC3621490/
https://europepmc.org/articles/PMC3621490/
Autor:
Susana Vaz Nery, Staci M. Rakowiecki, Yuanyuan Huang, Myrto Raftopoulou, Gord Fishell, Thomas Gridley, Heather A. Mason
Publikováno v:
Development (Cambridge, England). 132(19)
Numerous lines of evidence suggest that Notch signaling plays a pivotal role in controlling the production of neurons from progenitor cells. However,most experiments have relied on gain-of-function approaches because perturbation of Notch signaling r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456dc94298d7d05211159db34cdfb477
https://pubmed.ncbi.nlm.nih.gov/16120638
https://pubmed.ncbi.nlm.nih.gov/16120638