Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stacey R. Vlahakis"'
Autor:
David J. Schnepple, Alicia Algeciras-Schimnich, Gary D. Bren, Andrew D. Badley, Stacey R. Vlahakis, Sergey Trushin
Publikováno v:
Clinical Pharmacology & Therapeutics. 82:294-299
Human immunodeficiency virus (HIV) infection results in excessive apoptosis of infected and uninfected cells, mediated by host and viral factors present in plasma. As HIV protease inhibitors (PIs) have intrinsic antiapoptotic properties, we questione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf690c441dde9f00e69de35a0a652178
https://doi.org/10.1038/sj.clpt.6100140
https://doi.org/10.1038/sj.clpt.6100140
Publikováno v:
Apoptosis. 12:969-977
HIV protease inhibitors are an integral part of effective anti-HIV therapy. The drugs block HIV protease, prevent proper packaging of HIV virions, and decrease the HIV viral burden in the peripheral blood of infected individuals. In addition to direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa06955ab3e60fd6603d24aebf736ed1
https://doi.org/10.1007/s10495-007-0755-3
https://doi.org/10.1007/s10495-007-0755-3
Approach to salvage antiretroviral therapy in heavily antiretroviral-experienced HIV-positive adults
Publikováno v:
The Lancet Infectious Diseases. 6:496-507
Despite dramatic declines in HIV-associated morbidity and mortality as a result of highly active antiretroviral therapy, management of heavily treatment-experienced patients remains complex and challenging. Treatment response rates with subsequent an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becda01d7ee4f1b3a02ef051a59c19a1
https://doi.org/10.1016/s1473-3099(06)70550-3
https://doi.org/10.1016/s1473-3099(06)70550-3
Autor:
Carlos V. Paya, Nicholas Vlahakis, Angelina Villasis-Keever, Maria Vanegas, Stacey R. Vlahakis, Timothy S. Gomez
Publikováno v:
The Journal of Immunology. 169:5546-5554
Chemokine receptors are essential for triggering chemotaxis to immune cells; however, a number of them can also mediate death when engaged by nonchemokine ligands. When the chemokine receptor CXCR4 is engaged by stromal cell-derived factor (SDF1)α,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611a1ed82bad184d760e03acfd92748c
https://doi.org/10.4049/jimmunol.169.10.5546
https://doi.org/10.4049/jimmunol.169.10.5546
Autor:
Ronald G. Collman, Alicia Algeciras-Schimnich, Carrie J. Heppelmann, Angelina Villasis-Keever, Carlos V. Paya, Germán Bou, Stacey R. Vlahakis
Publikováno v:
Journal of Clinical Investigation. 107:207-215
There is considerable confusion concerning the mechanism of lymphocyte death during HIV infection. During the course of HIV infection, M-tropic viruses (R5) that use CCR5 chemokine coreceptors frequently evolve to T-tropic viruses (X4) that use CXCR4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e251fdea78c491ea3d87e94e2c762c33
https://doi.org/10.1172/jci11109
https://doi.org/10.1172/jci11109
Autor:
Mona Loutfy, Sergey Trushin, Daniel C. Douek, Alicia Algeciras Schimnich, David J. Schnepple, Stacey R. Vlahakis, Jason M. Brenchley, Zilin Nie, Colin Kovacs, Gary D. Bren, Sarah E. Warren, Andrew D. Badley
Publikováno v:
Journal of virology. 81(13)
Human immunodeficiency virus type 1 (HIV-1) infection causes apoptosis of infected CD4 T cells as well as uninfected (bystander) CD4 and CD8 T cells. It remains unknown what signals cause infected cells to die. We demonstrate that HIV-1 protease spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c932ab0839f90f2d19eeb063b9bf8538
https://pubmed.ncbi.nlm.nih.gov/17442709
https://pubmed.ncbi.nlm.nih.gov/17442709
Autor:
Stacey R. Vlahakis, Andrew D. Badley, Sergey Trushin, Sarah E. Warren, David J. Schnepple, Alicia Algeciras-Schimnich, Gary D. Bren
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 178(8)
HIV-1 infection causes the depletion of host CD4 T cells through direct and indirect (bystander) mechanisms. Although HIV Env has been implicated in apoptosis of uninfected CD4 T cells via gp120 binding to either CD4 and/or the chemokine receptor 4 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4783f4aa97585889786d186f918c48a8
https://pubmed.ncbi.nlm.nih.gov/17404265
https://pubmed.ncbi.nlm.nih.gov/17404265
Autor:
Stacey R, Vlahakis
Publikováno v:
Le Journal medical libanais. The Lebanese medical journal. 54(2)
Hepatitis C virus (HCV) infection is a major cause of liver disease and hepatocellular carcinoma worldwide, as well as the leading cause of liver transplantations in the United States. As a result of similar modes of transmission, approximately 30% o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d7051b6d82a2a664521ad59b09686df
https://pubmed.ncbi.nlm.nih.gov/17087002
https://pubmed.ncbi.nlm.nih.gov/17087002
Autor:
Stacey R. Vlahakis, Andrew D. Badley
Publikováno v:
Current opinion in clinical nutrition and metabolic care. 9(1)
Purpose of review Proteasome inhibitors are a novel class of drugs that alter normal cellular control of apoptosis. As such, they are being investigated as novel therapies to alter uncontrolled cellular proliferation and treat cancers. This review ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718082df87a9f1ac90bcf9e3e55cb9ec
https://pubmed.ncbi.nlm.nih.gov/16444818
https://pubmed.ncbi.nlm.nih.gov/16444818
