Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stacey R. Gish"'
Autor:
Ryan Z. Friedman, Stacey R. Gish, Holly Brown, Lindsey Brier, Nicole Howard, Tamara L. Doering, Michael R. Brent
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 3, Pp 815-822 (2018)
Received wisdom in the field of fungal biology holds that the process of editing a genome by transformation and homologous recombination is inherently mutagenic. However, that belief is based on circumstantial evidence. We provide the first direct me
Externí odkaz:
https://doaj.org/article/7d068d646ee04403ba4cbfca5f838b36
Autor:
Stacey R. Gish, Ezekiel J. Maier, Brian C. Haynes, Felipe H. Santiago-Tirado, Deepa L. Srikanta, Cynthia Z. Ma, Lucy X. Li, Matthew Williams, Erika C. Crouch, Shabaana A. Khader, Michael R. Brent, Tamara L. Doering
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills over 600,000 people annually. Here, we report integrated computational and experimental investigations of the role and mechanisms of transcriptional regulation
Externí odkaz:
https://doaj.org/article/d87a9ac21823494f9eabd63ca287c8ad
Autor:
Stacey R. Gish, Tamara L. Doering, Lindsey M. Brier, Michael R. Brent, Holly Brown, Ryan Z. Friedman, Nicole C Howard
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 8, Iss 3, Pp 815-822 (2018)
G3: Genes, Genomes, Genetics, Vol 8, Iss 3, Pp 815-822 (2018)
Received wisdom in the field of fungal biology holds that the process of editing a genome by transformation and homologous recombination is inherently mutagenic. However, that belief is based on circumstantial evidence. We provide the first direct me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535b335ae94283aad0fa5817e2cdae86
http://europepmc.org/articles/PMC5844303
http://europepmc.org/articles/PMC5844303
Autor:
Michael L. Skowyra, Tamara L. Doering, Ezekiel J. Maier, Stacey R. Gish, Alyssa Liane Marulli, Zhuo Alex Wang, Michael R. Brent, Brian C. Haynes
Publikováno v:
Genome Research. 25:690-700
Key steps in understanding a biological process include identifying genes that are involved and determining how they are regulated. We developed a novel method for identifying transcription factors (TFs) involved in a specific process and used it to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70f88dfa118e2a032855309dc970652
https://doi.org/10.1101/gr.184101.114
https://doi.org/10.1101/gr.184101.114
Autor:
Michael R. Brent, Christopher Fiore, Randall H. Brown, Holly Brown, Stacey R. Gish, Ezekiel J. Maier, Drew G. Michael
The ability to rationally manipulate the transcriptional states of cells would be of great use in medicine and bioengineering. We have developed an algorithm, NetSurgeon, which uses genome-wide gene-regulatory networks to identify interventions that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a85dbf6c0f7ada7845ba70580d9a63
https://europepmc.org/articles/PMC5127345/
https://europepmc.org/articles/PMC5127345/
Autor:
Ezekiel J. Maier, Michael R. Brent, Deepa Srikanta, Matthew Williams, Tamara L. Doering, Stacey R. Gish, Felipe H. Santiago-Tirado, Shabaana A. Khader, Lucy X. Li, Cynthia Z. Ma, Erika C. Crouch, Brian C. Haynes
Publikováno v:
mBio
mBio, Vol 7, Iss 2 (2016)
mBio, Vol 7, Iss 2, p e00313-16 (2016)
mBio, Vol 7, Iss 2 (2016)
mBio, Vol 7, Iss 2, p e00313-16 (2016)
Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills over 600,000 people annually. Here, we report integrated computational and experimental investigations of the role and mechanisms of transcriptional regulation in crypt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58295c572cba4ae62dc89bd74a42a6b9
http://europepmc.org/articles/PMC4850258
http://europepmc.org/articles/PMC4850258
Autor:
Hong Liu, Cara L. Griffith, Ezekiel J. Maier, Matthew Williams, Michael L. Skowyra, Zhuo Wang, Tamara L. Doering, Michael R. Brent, Stacey R. Gish, Nichole D. Salinas
Publikováno v:
Eukaryotic cell. 13(6)
Cryptococcus neoformans is an opportunistic yeast responsible for lethal meningoencephalitis in humans. This pathogen elaborates a polysaccharide capsule, which is its major virulence factor. Mannose constitutes over one-half of the capsule mass and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d82fb5a1a6383461426d15abb50bab8
https://pubmed.ncbi.nlm.nih.gov/24747214
https://pubmed.ncbi.nlm.nih.gov/24747214
Autor:
Elizabeth P. Held, Stacey R. Gish, Matthew Williams, Sarah J. Spencer, Tamara L. Doering, Michael L. Skowyra, Brian C. Haynes, Michael R. Brent
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002411 (2011)
PLoS Pathogens
PLoS Pathogens
Cryptococcus neoformans is an opportunistic fungal pathogen that causes serious human disease in immunocompromised populations. Its polysaccharide capsule is a key virulence factor which is regulated in response to growth conditions, becoming enlarge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d980b77439b627b5258bb283cae171bd
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22174677/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22174677/?tool=EBI
Autor:
Brian C Haynes, Michael L Skowyra, Sarah J Spencer, Stacey R Gish, Matthew Williams, Elizabeth P Held, Michael R Brent, Tamara L Doering
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002411 (2011)
Cryptococcus neoformans is an opportunistic fungal pathogen that causes serious human disease in immunocompromised populations. Its polysaccharide capsule is a key virulence factor which is regulated in response to growth conditions, becoming enlarge
Externí odkaz:
https://doaj.org/article/4c885fe6149e499cbd2bb0e1b99cc7b8