Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stacey L. Tannheimer"'
Autor:
Anella Yahiaoui, Sarah A Meadows, Rick A Sorensen, Zhi-Hua Cui, Kathleen S Keegan, Robert Brockett, Guang Chen, Christophe Quéva, Li Li, Stacey L Tannheimer
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171221 (2017)
Activated B-cell-like diffuse large B-cell lymphoma relies on B-cell receptor signaling to drive proliferation and survival. Downstream of the B-cell receptor, the key signaling kinases Bruton's tyrosine kinase and phosphoinositide 3-kinase δ offer
Externí odkaz:
https://doaj.org/article/a645d752f9ed4c7989cae7719beb9151
Autor:
Musong Kim, Mark A. Giembycz, Taruna Joshi, Dong Yan, Robert Newton, Omar Hamed, Gary B. Phillips, Michael Salmon, Clifford D. Wright, Stacey L. Tannheimer
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 360(2)
(R)-6-[(3-{[4-(5-{[2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl]amino}pent-1-yn-1-yl)phenyl] carbamoyl}phenyl)sulphonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide trifluoroacetic acid (GS-5759) is a bifunctional ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec5a2ff92e40be17acdbca537369144
https://pubmed.ncbi.nlm.nih.gov/27927912
https://pubmed.ncbi.nlm.nih.gov/27927912
Autor:
Katsuhito Yasuno, James R. Knight, S. Bulent Omay, Leman Sencar, Alexander O. Vortmeyer, Kaya Bilguvar, Geneive Carrión-Grant, Mehmet Bakırcığlu, Akdes Serin Harmanci, Murat Gunel, Selin Altınok, Jie Li, E. Zeynep Erson-Omay, Johannes Schramm, Stacey L Tannheimer, Hanwen Bai, Eric A. Sorensen, Sevin Turcan, Timothy A. Chan, Burcu Gülez, Matthias Simon, Marco Timmer, M. Necmettin Pamir, Phillip B. Murray, Ketu Mishra-Gorur, Leon D. Kaulen, Boris Krischek, Jennifer Moliterno, Angeliki Louvi, Victoria E. Clark, Süleyman Coşkun, Octavian Henegariu, Koray Özduman, A. Gulhan Ercan-Sencicek
Gliomas represent approximately 30\% of all central nervous system tumors and 80\% of malignant brain tumors(1). To understand the molecular mechanisms underlying the malignant progression of low-grade gliomas with mutations in IDH1 (encoding isocitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cc694b920ef59820a2d7d480702e73
https://hdl.handle.net/11443/2477
https://hdl.handle.net/11443/2477
Publikováno v:
Molecular Cancer Research. 2:643-652
A breast cancer cell line developed in our laboratory (SUM-52PE) has a 12-fold amplification and high-level overexpression of the oncogene fibroblast growth factor receptor 2 (FGFR2). Previously, nine different alternatively spliced FGFR2 variants we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d4e6735afb20278e788faf41021b3a4
https://doi.org/10.1158/1541-7786.643.2.11
https://doi.org/10.1158/1541-7786.643.2.11
Autor:
Zhi-Hua Cui, Michael Salmon, Clifford D. Wright, Melanie Doyle-Eisele, Eric A. Sorensen, Karin Rudolph, Edward G. Barrett, Gary B. Phillips, Philip J. Kuehl, Lafe J. Purvis, Christopher Royer, Musong Kim, Stacey L. Tannheimer, Kimberly C. Hartsough, Terry T. Gentzler, William R. Baker, Jacob D. McDonald
Publikováno v:
Pharmacology Research & Perspectives. 2
Bronchodilators are a central therapy for symptom relief in respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma, with inhaled β 2-adrenoceptor agonists and anticholinergics being the primary treatments available. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee0c3839086fffc4593bfbb9b2f09516
https://doi.org/10.1002/prp2.46
https://doi.org/10.1002/prp2.46
Autor:
Michael Salmon, Leena Patel, Stacey L. Tannheimer, Clifford D. Wright, Musong Kim, Gary B. Phillips, Zhi Hua Cui, William R. Baker, Eric A. Sorensen
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 349(1)
Inhaled long-acting β(2)-adrenoceptor agonists (LABA) that act as bronchodilators and the oral anti-inflammatory phosphodiesterase 4 (PDE4) inhibitor roflumilast are both approved therapies for chronic obstructive pulmonary disease (COPD). Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec1f00994e36decfd1eb9ed38147c53
https://pubmed.ncbi.nlm.nih.gov/24513870
https://pubmed.ncbi.nlm.nih.gov/24513870
Publikováno v:
Molecular Carcinogenesis. 25:48-54
Carcinogenic polycyclic aromatic hydrocarbons and a halogenated aromatic hydrocarbon, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), were evaluated for their effects on intracellular Ca2+ in the human mammary epithelial cell line MCF-10A. After two 18-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b9fa117cc5a68b1fb354c8b43607ef6
https://doi.org/10.1002/(sici)1098-2744(199905)25:1<48::aid-mc6>3.0.co
https://doi.org/10.1002/(sici)1098-2744(199905)25:1<48::aid-mc6>3.0.co
Publikováno v:
Carcinogenesis. 19:1291-1297
Previous studies in this laboratory have shown that polycyclic aromatic hydrocarbons, such as benzo[a]pyrene (BaP), and certain halogenated aromatic hydrocarbons, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), modulate receptor signaling pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94157724e33fa0d2c587857f00b4e604
https://doi.org/10.1093/carcin/19.7.1291
https://doi.org/10.1093/carcin/19.7.1291
Publikováno v:
D35. PHOSPHODIESTERASE INHIBITORS AS THERAPEUTICS FOR LUNG DISEASES.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4ebd05cd7f61a3e335ef7d76a91f1fd
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5707
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5707
Publikováno v:
D35. PHOSPHODIESTERASE INHIBITORS AS THERAPEUTICS FOR LUNG DISEASES.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e80e09b240530c3c8d42b986cc6d5c5
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5703
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5703