Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stacey L. Demento"'
Autor:
Tarek M. Fahmy, W. Mark Saltzman, Ira Mellman, Michel Ledizet, Craig D. Platt, Erol Fikrig, Harald G. Foellmer, Stephanie C. Eisenbarth, Richard A. Flavell, Stacey L. Demento, Michael J. Caplan
Publikováno v:
Vaccine. 27:3013-3021
Innate immune system activation is a critical step in the initiation of an effective adaptive immune response; therefore, activation of a class of innate pathogen receptors called pattern recognition receptors (PRR) is a central feature of many adjuv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290f2192ed4d26b01c589906bc3cbb70
https://doi.org/10.1016/j.vaccine.2009.03.034
https://doi.org/10.1016/j.vaccine.2009.03.034
Autor:
Michael Look, David Gonzalez, Ann Habermann, Tarek M. Fahmy, Jason Park, Steven M. Jay, Stacey L. Demento, Stephen H. Wrzesinski, Ragy Ragheb, Jason M. Criscione, Atu Agawu, Eric Stern, Richard A. Flavell, Paula Licona Limon, Anthony F. Ferrandino
The tumour microenvironment thwarts conventional immunotherapy through multiple immunologic mechanisms, such as the secretion of the transforming growth factor-β (TGF-β), which stunts local tumour immune responses. Therefore, high doses of interleu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715a4ca45d5dcf38bfd5cbc634720230
https://europepmc.org/articles/PMC3601683/
https://europepmc.org/articles/PMC3601683/
Autor:
Tarek M. Fahmy, Eric Stern, Jason M. Criscione, Jacob E. Tulipan, Susan M. Kaech, Stacey L. Demento, Weiguo Cui
Publikováno v:
Biomaterials. 33(19)
Particulate vaccines are emerging promising technologies for the creation of tunable prophylactics against a wide variety of conditions. Vesicular and solid biodegradable polymer platforms, exemplified by liposomes and polyesters, respectively, are t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c29d0753bb97bf018b4d5252d544da8
https://pubmed.ncbi.nlm.nih.gov/22484047
https://pubmed.ncbi.nlm.nih.gov/22484047
Autor:
Arunima Bandyopadhyay, Stacey L. Demento, Linda K. Bockenstedt, Rebecca L. Fine, Tarek M. Fahmy
Dendritic-cell (DC) targeted antigen delivery systems hold promise for enhancing vaccine efficacy and delivery of therapeutics. However, it is not known how the number and density of targeting ligands on such systems may affect DC function and subseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1fee5953c74695b193836489da5c27
https://europepmc.org/articles/PMC4570971/
https://europepmc.org/articles/PMC4570971/
Publikováno v:
Trends in biotechnology. 29(6)
Vaccine development has progressed significantly and has moved from whole microorganisms to subunit vaccines that contain only their antigenic proteins. Subunit vaccines are often less immunogenic than whole pathogens; therefore, adjuvants must ampli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136a8b4550b51224d17092d6e556b938
https://pubmed.ncbi.nlm.nih.gov/21459467
https://pubmed.ncbi.nlm.nih.gov/21459467
Autor:
Michel Ledizet, Weiguo Cui, Tarek M. Fahmy, Stacey L. Demento, Michael J. Caplan, Nathalie Bonafé, Erol Fikrig, Susan M. Kaech
Vaccines that activate humoral and cell-mediated immune responses are urgently needed for many infectious agents, including the flaviviruses dengue and West Nile (WN) virus. Vaccine development would be greatly facilitated by a new approach, in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fd72f69a894eef6d07d23412bbe6ee
https://europepmc.org/articles/PMC3753007/
https://europepmc.org/articles/PMC3753007/
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2009
Modulating immune responses to pathogen invasion and even tumors is a major goal in immunotherapy. T cells play a central role in these responses. Progress towards that goal is accomplished by stimulating the antigen-specific T cell immune response i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5febd3b87b7a8ed4e9538702f59c383d
https://pubmed.ncbi.nlm.nih.gov/19963488
https://pubmed.ncbi.nlm.nih.gov/19963488
Autor:
Tarek M. Fahmy, Mark A. Reed, Ryan P. Murelli, Eric Stern, David Spiegel, Stacey L. Demento, David J. Mooney, Steven M. Jay, Tadeusz Malinski
Bioactive, patterned micro- and nanoscale surfaces that can be spatially engineered for three-dimensional ligand presentation and sustained release of signaling molecules represent a critical advance for the development of next-generation diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974a4917d3cdd6b1c30911860f5e049e
https://europepmc.org/articles/PMC2863321/
https://europepmc.org/articles/PMC2863321/
Publikováno v:
Nanomedicine (London, England). 3(3)
Vaccines for many infectious diseases are poorly developed or simply unavailable. There are significant technological and practical design issues that contribute to this problem; thus, a solution to the vaccine problem will require a systematic appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f150e121c408972899f7d838b7ee3d
https://pubmed.ncbi.nlm.nih.gov/18510429
https://pubmed.ncbi.nlm.nih.gov/18510429