Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stacey Krumholtz"'
Publikováno v:
Cancers, Vol 13, Iss 7, p 1555 (2021)
Noncoding RNAs (ncRNAs) have emerged as a novel class of genomic regulators, ushering in a new era in molecular biology. With the advent of advanced genetic sequencing technology, several different classes of ncRNAs have been uncovered, including mic
Externí odkaz:
https://doaj.org/article/70afaea98f1c4b36a7042e965d3b49a4
Autor:
Christian A. Smith, Hidehiro Okura, James T. Rutka, Madeline Hayes, Michael S. Taccone, Uswa Shahzad, Xi Huang, W. Brent Derry, Joji Ishida, Stacey Krumholtz, Julia Edgar, Kyle Gouveia, Sachin Kumar, Coco Mine, Michael D. Taylor
Publikováno v:
Neuro Oncol
For decades, cell biologists and cancer researchers have taken advantage of non-murine species to increase our understanding of the molecular processes that drive normal cell and tissue development, and when perturbed, cause cancer. The advent of who
Autor:
Stacey Krumholtz, James T. Rutka, Dilakshan Srikanthan, Joji Ishida, Randy Van Ommeren, Michael S. Taccone
Publikováno v:
Chinese Neurosurgical Journal, Vol 7, Iss 1, Pp 1-11 (2021)
Chinese Neurosurgical Journal
Chinese Neurosurgical Journal
Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain tumor and the leading cause of brain tumor–related death in children. As several clinical trials over the past few decades have led to no significant improvements in outcome, the c
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1555, p 1555 (2021)
Cancers, Vol 13, Iss 1555, p 1555 (2021)
Simple Summary Since the completion of the Human Genome Project, noncoding RNAs (ncRNAs) have emerged as an important class of genetic regulators. Several classes of ncRNAs, which include microRNAs (miRNAs), long noncoding RNAs (lncRNAs), circular RN
Autor:
Nesrin Sabha, Alexandra N. Riemenschneider, Stacey Krumholtz, Jason Karamchandani, Michael J. Johnston, Sunit Das, James T. Rutka, Jonathan K. Watts, Jenny Wang, Christian A. Smith, Marco Gallo, Roel G.W. Verhaak, Uswa Shahzad, Christopher I. Li, Pranathi Meda, Frederick S. Varn
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults, with a median survival of just over one year. The failure of available treatments to achieve remission in patients with GBM has been attributed to the presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa19a85edb46e22a3e04eda889d9a94
https://doi.org/10.1101/2020.09.05.284349
https://doi.org/10.1101/2020.09.05.284349
Autor:
Brian Golbourn, Naohide Fujita, Andrew Bondoc, Nesrin Sabha, Christian A. Smith, Kristina Mikloska, Saira Alli, James T. Rutka, Stacey Krumholtz, Amanda Luck, Joji Ishida, Colin Maslink, Dilakshan Srikanthan, Kullervo Hynynen
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 330
Diffuse intrinsic pontine glioma (DIPG) is a surgically unresectable and devasting tumour in children. To date, there are no effective chemotherapeutics despite a myriad of clinical trials. The intact blood-brain barrier (BBB) is likely responsible f
Autor:
Michael D. Taylor, Gelareh Zadeh, Rob A. Cairns, Vijay Ramaswamy, Marc Remke, Christian A. Smith, Gregory N. Fuller, Michael S. Taccone, Alan Chalil, James T. Rutka, Stacey Krumholtz, William L. Stanford, Brian Golbourn, Xi Huang, Danielle Mackenzie, Cynthia Hawkins, Susan Younger, Sameer Agnihotri, Paul S. Mischel, Patricia Rakopoulos
Publikováno v:
Cancer Research. 76:4708-4719
Proliferating cancer cells are characterized by high rates of glycolysis, lactate production, and altered mitochondrial metabolism. This metabolic reprogramming provides important metabolites for proliferation of tumor cells, including glioblastoma.