Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stacey K Moreno"'
Autor:
Dhifaf Sarhan, Svetlana Gaidarova, Ryan Bjordahl, Valarie McCullar, Phillip Dougherty, Yenan T. Bryceson, Peter Howard, Frank Cichocki, Scott Wolchko, Katie Tuininga, Emily Taras, Stewart E Abbot, Jeffrey S. Miller, Bin Zhang, Sarah Cooley, Heinrich Schlums, Bahram Valamehr, Stacey K Moreno, Bruce R. Blazar, Betsy Rezner, Daniel Shoemaker, Paul Rogers
Publikováno v:
Cancer Research. 77:5664-5675
Maturation of human natural killer (NK) cells as defined by accumulation of cell-surface expression of CD57 is associated with increased cytotoxic character and TNF and IFNγ production upon target-cell recognition. Notably, multiple studies point to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c3f5c4bd5fa9e74fbf60a17225bf3b
https://doi.org/10.1158/0008-5472.can-17-0799
https://doi.org/10.1158/0008-5472.can-17-0799
Autor:
Jolanta Stefanski, Raedun Clarke, Isabelle Riviere, Yi-Shin Lai, Chelsea Ruller, Megan Robinson, Pieter Lindenbergh, Ramzey Abujarour, Helen Chu, Alec Witty, Jaeger Davis, Amanda Medcalf, Jason Dinella, Thomas H. Lee, Bahram Valamehr, Juan Zhen, Michel Sadelain, Janel Huffman, Mochtar Pribadi, Greg Bonello, Stacey K. Moreno, Xiuyan Wang, Sjoukje J. C. van der Stegen
Publikováno v:
Cancer Research. 79:LB-073
Adoptive transfer of autologous T cells expressing chimeric antigen receptor (CAR) has shown great promise in the treatment of blood malignancies. Challenges for the application of current CAR T cell therapies to broader and more diverse patient popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bc49abfa569730f6bd47abf360dec6d
https://doi.org/10.1158/1538-7445.am2019-lb-073
https://doi.org/10.1158/1538-7445.am2019-lb-073
Autor:
Salome Murinello, Matthew S. Macauley, Peter D. Westenskow, Martin Friedlander, Stacey K. Moreno, Susumu Sakimoto
Publikováno v:
Journal of Visualized Experiments.
Microglia are the tissue resident macrophages of the central nervous system (CNS) and they perform a variety of functions that support CNS homeostasis, including phagocytosis of damaged synapses or cells, debris, and/or invading pathogens. Impaired p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9595af99f1fbdaba369fadff148ca7c3
https://doi.org/10.3791/54677
https://doi.org/10.3791/54677
Autor:
Stacey K. Moreno, Scott Wolchko, Frank Cichocki, Brian Groff, Svetlana Gaidarova, Ryan Bjordahl, Dan S. Kaufman, Bruce R. Blazar, Betsy Rezner, Ramzey Abujarour, Thomas H. Lee, Sarah Cooley, Greg Bonello, Stewart Abbot, Raedun Clarke, Paul Rogers, Jeffrey S. Miller, David H. McKenna, Darin Sumstad, Megan Robinson, Daniel Shoemaker, Weijie Lan, Bahram Valamehr
Publikováno v:
Blood. 130:656-656
Natural killer (NK) cells represent a lineage of immune cells capable of direct cytotoxicity against tumor cells and are a critical source of key inflammatory cytokines such as interferon (IFN)-γ and tumor necrosis factor (TNF). NK cell function is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a417c938203629dab7a9147fbd7817df
https://doi.org/10.1182/blood.v130.suppl_1.656.656
https://doi.org/10.1182/blood.v130.suppl_1.656.656
Autor:
Michael I. Dorrell, Liliana P Paris, Carli M Wittgrove, Edith Aguilar, Mollie S.H. Friedlander, Yoshihiko Usui, Stacey K. Moreno, Daniel Feitelberg, Peter D. Westenskow, Martin Friedlander, Toshihide Kurihara, Susumu Sakimoto
Functional interactions between neurons, vasculature, and glia within neurovascular units are critical for maintenance of the retina and other CNS tissues. For example, the architecture of the neurosensory retina is a highly organized structure with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461299a637f51416979b608fe40788c2
https://europepmc.org/articles/PMC4497761/
https://europepmc.org/articles/PMC4497761/
Autor:
Stacey K. Moreno, Michael I. Dorrell, Martin Friedlander, Eyal Banin, Edith Aguilar, Matthew R. Ritter
Publikováno v:
Journal of Clinical Investigation. 116:3266-3276
Vision loss associated with ischemic diseases such as retinopathy of prematurity and diabetic retinopathy are often due to retinal neovascularization. While significant progress has been made in the development of compounds useful for the treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ebceb10deacec1eab3909d98c01d5d
https://doi.org/10.1172/jci29683
https://doi.org/10.1172/jci29683
Publikováno v:
Blood. 103:3420-3427
Adult bone marrow contains a population of hematopoietic stem cells (HSCs) that can give rise to cells capable of targeting sites of neovascularization in the peripheral or retinal vasculature. However, relatively little is known about the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e9edca5973c4157a3113126e78c39a
https://doi.org/10.1182/blood-2003-09-3012
https://doi.org/10.1182/blood-2003-09-3012
Autor:
Michael I. Dorrell, Lawrence F. Eichenfield, John Reinisch, Steven B. Cohen, Joshua Ney, Ralph Holmes, Bari B. Cunningham, Jeffrey Rubens, Martin Friedlander, Stacey K. Moreno, Matthew R. Ritter, David F. Friedlander, James N. Bergman, Thomas Veccione, Sheila Fallon Friedlander
Publikováno v:
Lymphatic Research and Biology. 1:291-299
Hemangiomas are benign endothelial tumors. Often referred to as hemangiomas of infancy (HOI), these tumors are the most common tumor of infancy. Most of these lesions proliferate rapidly in the first months of life, and subsequently slowly involute d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667a151138ceb45b471bf33cadf38704
https://doi.org/10.1089/153968503322758094
https://doi.org/10.1089/153968503322758094
Autor:
Ramzey Abujarour, Svetlana Gaidarova, Stewart Abbot, Paul Rogers, Scott Wolchko, Bruce R. Blazar, Bahram Valamehr, Daniel Shoemaker, Brian Groff, Jeffrey S. Miller, Bruce Walcheck, Dave Robbins, Weijie Lan, Frank Cichocki, Raedun Clarke, Betsy Rezner, Thomas H. Lee, Sarah Cooley, Ryan Bjordahl, Greg Bonello, Stacey K. Moreno, Matthieu Bauer
Publikováno v:
Cancer Research. 77:3755-3755
The unique attributes of a combinatorial tumor recognition system, diminished off-tumor cytotoxicity, and multifaceted effector function make natural killer (NK) cells a prime candidate for a universal approach to cancer immunotherapy. In addition, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c7d0dff377310392e56c16a0d51409f
https://doi.org/10.1158/1538-7445.am2017-3755
https://doi.org/10.1158/1538-7445.am2017-3755
Autor:
Sarah Borchelt, Ryan P Larson, Ian Hardy, Christian Maine, Jason Fontenot, Daniel Shoemaker, David J. Robbins, Sarah Reynal, Christopher Truong, Mohsen Sabouri, Miguel Meza, Mirna Mujacic, Heather Foster, Lucas Thompson, Stacey K. Moreno, Jon Rosen, Betsy Rezner, Eigen Peralta
Publikováno v:
Blood. 128:4712-4712
Adoptive cellular therapies using engineered chimeric antigen receptor T cells (CAR-T cells) are rapidly emerging as a highly effective treatment option for a variety of life-threatening hematological malignancies. Small molecule-mediated modulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0424ef073adab5f718a1311ae3231cf1
https://doi.org/10.1182/blood.v128.22.4712.4712
https://doi.org/10.1182/blood.v128.22.4712.4712