Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stacey Drabic"'
Autor:
Subramanya Karanth, Rakesh Dixit, Patricia C. Ryan, William O. Iverson, Stacey Drabic, Terry O'Day, Simone M. Nicholson, Kerry A. Casey, Michele Gunsior, Stephen Scott, Halie Cook
Publikováno v:
Br J Pharmacol
Background and purpose Inhibition of the T- and B-cell interaction through the CD40/CD40 ligand (L) axis is a favourable approach for inflammatory disease treatment. Clinical studies of anti-CD40L molecules in autoimmune diseases have met challenges
Autor:
Wright Nathan E, Sean S. Parghi, James Taylor, Matthew R. Warr, Stacey Drabic, Angie Hammond, Ethan Grant
Publikováno v:
Poster Presentations.
Background A hallmark of lupus is the presence of antinuclear autoantibodies, including those against RNA-protein complexes and double-stranded DNA (dsDNA).1,2 FcγR-mediated internalization of these nucleic acid:autoantibody immune complexes results
Autor:
Isharat Yusuf, Stacey Drabic, Albulescu Marius, Melissa de los Reyes, Rachel Ettinger, Manuel Baca, Jodi L. Karnell, Li Yan, Ximing Xiong, Thomas Thisted, L. Wang, Ulf Müller-Ladner, David Howe, Jing Li, Jorn Drappa, Steven Eck, Rachel Moate, Ronald Herbst, Michele Gunsior, Katie Streicher, Vaheh Oganesyan
Publikováno v:
Science Translational Medicine. 11
The CD40/CD40L axis plays a central role in the generation of humoral immune responses and is an attractive target for treating autoimmune diseases in the clinic. Here, we report the generation and clinical results of a CD40L binding protein, VIB4920
Autor:
Luba Grinberg, Sandrina Phipps, Stacey Drabic, Thomas Thisted, Andrew D. Ferguson, Lin Wang, Vaheh Oganesyan, Benoy Chacko, Manuel Baca
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 69:1045-1048
Tn3 proteins are a novel class of binding molecules based on the third fibronectin type III domain of human tenascin C. Target-specific Tn3 proteins are selected from combinatorial libraries in which three surface-exposed loops have been diversified.
Autor:
Anthony J. Coyle, Katherine A. Fitzgerald, Bo Chen, Ann Marshak-Rothstein, Peggy Parroche, Peter Naworth, Stacey Drabic, Ana M. Avalos, Douglas T. Golenbock, Mary K. Crow, Greg La Rosa, Eicke Latz, Peter A. Kiener, Cherilyn M. Sirois, Laurent P. Audoly, Herren Wu, Jing Hua, Angelika Bierhaus, Su-Yau Mao, Jane Tian, Kannaki Senthil, Ling-Ling An
Publikováno v:
Nature immunology. 8(5)
Increased concentrations of DNA-containing immune complexes in the serum are associated with systemic autoimmune diseases such as lupus. Stimulation of Toll-like receptor 9 (TLR9) by DNA is important in the activation of plasmacytoid dendritic cells
Autor:
Jane Tian, Peter Naworth, Stacey Drabic, Su-Yau Mao, Kannaki Senthil, Greg La Rosa, Ling-Ling An, Peggy Parroche, Peter A. Kiener, Katherine A. Fitzgerald, Douglas T. Golenbock, Cherilyn M. Sirois, Anthony J. Coyle, Mary K. Crow, Ana M. Avalos, Bo Chen, Laurent P. Audoly, Eicke Latz, Jing Hua, Angelika Bierhaus, Ann Marshak-Rothstein, Herren Wu
Publikováno v:
Nature Immunology. 8:780-780
Corrigendum: Toll-like receptor 9—dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE