Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stacey Conarello"'
Autor:
Peining Tao, Stacey Conarello, Thomas P. Wyche, Nanyan Rena Zhang, Keefe Chng, John Kang, Theodore R. Sana
Publikováno v:
Metabolites, Vol 14, Iss 3, p 159 (2024)
Type 2 diabetes (T2D) is a global public health issue characterized by excess weight, abdominal obesity, dyslipidemia, hyperglycemia, and a progressive increase in insulin resistance. Human population studies of T2D development and its effects on sys
Externí odkaz:
https://doaj.org/article/50ab0f0e80484fc1978aed52a6d43461
Autor:
Veronica Clavijo Jordan, Catherine D. G. Hines, Liza T. Gantert, Shubing Wang, Stacey Conarello, Christian Preihs, Sara Chirayil, Michael Klimas, Jeffrey L. Evelhoch, A. Dean Sherry
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Non-invasive beta cell function measurements may provide valuable information for improving diabetes diagnostics and disease management as the integrity and function of pancreatic beta cells have been found to be compromised in Type-1 and Type-2 diab
Externí odkaz:
https://doaj.org/article/fc97c59679444ff39cabae396fbd4b0b
Autor:
Thomas P. Roddy, Gowri Bhat, Kithsiri Herath, Ling Kang, Sheo B. Singh, Stacey Conarello, Deborah Slipetz, David E. Kelley, Carlos G. Rodriguez, Andrea R. Nawrocki, Mark D. Erion, Stephen F. Previs, Jenna L. Terebetski
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 315:E63-E71
An increased contribution of de novo lipogenesis (DNL) may play a role in cases of dyslipidemia and adipose accretion; this suggests that inhibition of fatty acid synthesis may affect clinical phenotypes. Since it is not clear whether modulation of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52dab4615e55e4404be4a1e697b609a0
https://doi.org/10.1152/ajpendo.00010.2017
https://doi.org/10.1152/ajpendo.00010.2017
Autor:
Victoria Plamadeala Johnson, Emanuel Zycband, Stacey Conarello, Yonghua Zhu, David E. Kelley, Michael Staup, Jin Shang, Mark D. Erion, Dan Xie, Keefe Chng, Gladys Arreaza, Stephen F. Previs, Liangsu Wang, Margaret van Heek, Diane Levitan, Yixin Wang, Karni Schlessinger, Sandra C. Souza, Ying Chen, Franklin Liu
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 312:E235-E243
Insulin resistance and diabetes can develop spontaneously with obesity and aging in rhesus monkeys, highly similar to the natural history of obesity, insulin resistance, and progression to type 2 diabetes in humans. The current studies in obese rhesu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea6be096903d99992ef951ec8277fde
https://doi.org/10.1152/ajpendo.00398.2016
https://doi.org/10.1152/ajpendo.00398.2016
Autor:
Larry Handt, Richard Raubertas, David B. Gilberto, Liza Gantert, Jeremy Beech, Stacey Conarello, Tasha Gray, Steven Fox, Walter Knapp, Wendy J. Watson, Cai Li, Ashleigh Bone, Scott Tiesma, Patricia A. Rebbeck
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Until recently, preclinical and clinical work on diabetes has focused on the understanding of blood glucose elevation and its detrimental metabolic sequelae. The advent of continuous glucose monitoring (CGM) technology now allows real time monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fce95e5fcc96038c0b477682a7550b7
http://europepmc.org/articles/PMC6363759
http://europepmc.org/articles/PMC6363759
Autor:
Stephen F, Previs, Kithsiri, Herath, Andrea R, Nawrocki, Carlos G, Rodriguez, Deborah, Slipetz, Sheo B, Singh, Ling, Kang, Gowri, Bhat, Thomas P, Roddy, Stacey, Conarello, Jenna, Terebetski, Mark D, Erion, David E, Kelley
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 315(1)
An increased contribution of de novo lipogenesis (DNL) may play a role in cases of dyslipidemia and adipose accretion; this suggests that inhibition of fatty acid synthesis may affect clinical phenotypes. Since it is not clear whether modulation of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5152dc26830685b90b088855db8d7ae
https://pubmed.ncbi.nlm.nih.gov/29351479
https://pubmed.ncbi.nlm.nih.gov/29351479
Autor:
Aleksandr Petrov, Wen Feng, Ann E. Weber, Effie Tozzo, Lisa LaFranco Scheuch, Shiyao Xu, Wei Zhu, Nancy A. Thornberry, Dinko Gonzalez Trotter, Rory J. Rohm, Franklin Liu, Ku Lu, Michelle Bunzel, David E. Kelley, Stacey Conarello, Jinqi Liu, Corin O. Miller, Xiaoda Niu, Huaibing He, Ronald E. Painter, Ying Li, Daniel M. Kemp, Ying Qian, Maria E. Trujillo, Mark D. Erion, Liyang Wang, Iyassu K. Sebhat, Gaochao Zhou, Michael Klimas, Marie A. Holahan, Marc M. Kurtz, George J. Eiermann, Guillermo Fernandez, Bindu Bennet, Juliann Ehrhart, Tesfaye Biftu, Aimie Ogawa, Sandra C. Souza, Cai Li, Srinivasa Prahalada, James A. Milligan, Hong-Ping Guan, Danqing Feng, Robert W. Myers, Douglas Wisniewski, Xiaodong Yang, Daniel Rubins, Hongwu Wang, Margaret van Heek
Publikováno v:
Science (New York, N.Y.). 357(6350)
Hitting a dozen enzymes with one drug The adenosine monophosphate-activated protein kinase (AMPK) controls cellular energy status. AMPK is activated when energy levels fall. This stimulates adenosine triphosphate (ATP)-generating pathways that promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2391508ed314a4efb53e289ff8766448
https://pubmed.ncbi.nlm.nih.gov/28774917
https://pubmed.ncbi.nlm.nih.gov/28774917
Autor:
Stacey Conarello, Bei B. Zhang, John Ronan, Zhihua Li, John Woods, David E. Moller, Ranabir Sinha Roy, Emanuel I. Zycband, Guoqiang Jiang, Lan Zhu, Franklin Liu, Nancy A. Thornberry
Publikováno v:
Proceedings of the National Academy of Sciences. 100:6825-6830
Dipeptidyl peptidase IV (DP-IV), a member of the prolyl oligopeptidase family of peptidases, is involved in the metabolic inactivation of a glucose-dependent insulinotropic hormone, glucagon-like peptide 1 (GLP-1), and other incretin hormones. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e03a1895b1667ff00178a4882faf905
https://doi.org/10.1073/pnas.0631828100
https://doi.org/10.1073/pnas.0631828100
Autor:
Lan Zhu, John Woods, Guoqiang Jiang, Franklin Liu, R. Sinha Roy, John Ronan, Stacey Conarello, Bei Zhang, James Mu, Zhihua Li, Emanuel Zycband, Maureen J. Charron
Publikováno v:
Diabetologia. 50(1)
Under normal physiological conditions, glucagon signalling is important in glucose homeostasis. Hyperglucagonaemia or altered insulin:glucagon ratio plays a role in maintaining hyperglycaemia in subjects with type 2 diabetes. It has been reported tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d7e6745ebdb26595165bbbe8f079f8
https://pubmed.ncbi.nlm.nih.gov/17131145
https://pubmed.ncbi.nlm.nih.gov/17131145
Autor:
Xiao-Ming Guan, Ellen L. Air, Mathias Z. Strowski, Bei B. Zhang, Stacey Conarello, Kun Liu, Stephen C. Woods, Stephen C. Benoit, Gino Salituro
Publikováno v:
Nature medicine. 8(2)
Obesity and insulin resistance are major risk factors for a number of metabolic disorders, such as type 2 diabetes mellitus1,2. Insulin has been suggested to function as one of the adiposity signals to the brain for modulation of energy balance. Admi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9029fc57f2c501c266d14625e0db1e0
https://pubmed.ncbi.nlm.nih.gov/11821903
https://pubmed.ncbi.nlm.nih.gov/11821903