Evidence for direct CO 2 -mediated alterations in cerebral oxidative metabolism in humans.

Autor: Caldwell HG; Centre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, British Columbia, Canada., Hoiland RL; Centre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, British Columbia, Canada.; Department of Anesthesiology, Pharmacology and Therapeutics, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada.; International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, British Columbia, Canada.; Collaborative Entity for REsearching Brain Ischemia (CEREBRI), University of British Columbia, Vancouver, British Columbia, Canada., Bain AR; Department of Kinesiology, Faculty of Human Kinetics, University of Windsor, Windsor, Ontario, Canada., Howe CA; Centre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, British Columbia, Canada., Carr JMJR; Centre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, British Columbia, Canada., Gibbons TD; Centre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, British Columbia, Canada., Durrer CG; Centre for Physical Activity Research, Rigshospitalet, Copenhagen, Denmark., Tymko MM; Division of Critical Care Medicine, Department of Medicine, Faculty of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.; Human Cerebrovascular Physiology Laboratory, Department of Human Health and Nutritional Sciences, College of Biological Science, University of Guelph, Guelph, Ontario, Canada., Stacey BS; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Bailey DM; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Sekhon MS; International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, British Columbia, Canada.; Collaborative Entity for REsearching Brain Ischemia (CEREBRI), University of British Columbia, Vancouver, British Columbia, Canada.; Division of Critical Care Medicine, Department of Medicine, Faculty of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada., MacLeod DB; Human Pharmacology and Physiology Lab, Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA., Ainslie PN; Centre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, British Columbia, Canada.

Publikováno v: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2024 Sep; Vol. 240 (9), pp. e14197. Date of Electronic Publication: 2024 Jul 03.

Severe hypoxaemic hypercapnia compounds cerebral oxidative-nitrosative stress during extreme apnoea: Implications for cerebral bioenergetic function.

Autor: Bailey DM; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Glamorgan, UK., Bain AR; Department of Kinesiology, Faculty of Human Kinetics, University of Windsor, Windsor, ON, Canada., Hoiland RL; Department of Anaesthesiology, Pharmacology and Therapeutics, Vancouver General Hospital, West 12th Avenue, University of British Columbia, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada., Barak OF; Department of Integrative Physiology, School of Medicine, University of Split, Split, Croatia.; Department of Sports Medicine, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia., Drvis I; School of Kinesiology, University of Zagreb, Zagreb, Croatia., Stacey BS; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Glamorgan, UK., Iannetelli A; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Glamorgan, UK., Davison GW; Department of Exercise Biochemistry and Physiology, Sport and Exercise Science Research Institute, Ulster University Belfast, United Kingdom of Great Britain and Northern Ireland, Ulster, UK., Dahl RH; Department of Radiology, University Hospital Rigshospitalet, Copenhagen, Denmark., Berg RMG; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Glamorgan, UK.; Department of Biomedical Sciences, University of Copenhagen, Denmark., MacLeod DB; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA., Dujic Z; Department of Integrative Physiology, School of Medicine, University of Split, Split, Croatia., Ainslie PN; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Glamorgan, UK.; School of Health and Exercise Sciences, Faculty of Health and Social Development, Center for Heart Lung and Vascular Health, University of British Columbia, Kelowna, BC, Canada.

Publikováno v: The Journal of physiology [J Physiol] 2024 Nov; Vol. 602 (21), pp. 5659-5684. Date of Electronic Publication: 2024 Feb 13.

Cognition is selectively impaired in males with spinal pain: A retrospective analysis of data from the Longitudinal Study of Ageing Danish Twins.

Autor: Byfield DC; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Stacey BS; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Bailey DM; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK.

Publikováno v: Experimental physiology [Exp Physiol] 2024 Apr; Vol. 109 (4), pp. 474-483. Date of Electronic Publication: 2024 Feb 17.

Acute hypoxia impairs posterior cerebral bioenergetics and memory in man.

Autor: Ando S; Graduate School of Informatics and Engineering, The University of Electro-Communications, Tokyo, Japan., Tsukamoto H; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK.; Faculty of Sports Science, Waseda University, Saitama, Japan., Stacey BS; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Washio T; Department of Biomedical Engineering, Toyo University, Kawagoe, Saitama, Japan., Owens TS; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Calverley TA; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Fall L; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Marley CJ; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Iannetelli A; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Hashimoto T; Faculty of Sport and Health Science, Ritsumeikan University, Shiga, Japan., Ogoh S; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK.; Department of Biomedical Engineering, Toyo University, Kawagoe, Saitama, Japan., Bailey DM; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK.

Publikováno v: Experimental physiology [Exp Physiol] 2023 Dec; Vol. 108 (12), pp. 1516-1530. Date of Electronic Publication: 2023 Oct 29.

Hemoglobin and cerebral hypoxic vasodilation in humans: Evidence for nitric oxide-dependent and S -nitrosothiol mediated signal transduction.

Autor: Hoiland RL; Department of Anesthesiology, Pharmacology and Therapeutics, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada.; International Collaboration on Repair Discoveries, Vancouver, BC, Canada., MacLeod DB; Human Pharmacology & Physiology Lab, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA., Stacey BS; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Caldwell HG; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada., Howe CA; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada., Nowak-Flück D; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada., Carr JM; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada., Tymko MM; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada., Coombs GB; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada., Patrician A; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada., Tremblay JC; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada., Van Mierlo M; Department of Biomechanical Engineering, University of Twente, Enschede, The Netherlands., Gasho C; Department of Medicine, Division of Pulmonary and Critical Care, Loma Linda University School of Medicine, Loma Linda, CA, USA., Stembridge M; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK., Sekhon MS; International Collaboration on Repair Discoveries, Vancouver, BC, Canada.; Djavad Mowafaghian Centre for Brain Health, Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Division of Critical Care Medicine, Department of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada., Bailey DM; Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK., Ainslie PN; Centre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, BC, Canada.

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2023 Sep; Vol. 43 (9), pp. 1519-1531. Date of Electronic Publication: 2023 Apr 12.