Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Stacey Allen"'
Autor:
Jing Liu, Jake S. O’Donnell, Juming Yan, Jason Madore, Stacey Allen, Mark J. Smyth, Michele W. L. Teng
Publikováno v:
OncoImmunology, Vol 8, Iss 5 (2019)
Adjuvant immunotherapies targeting CTLA4 or PD-1 recently demonstrated efficacy in the treatment of earlier stages of human cancer. We previously demonstrated using mouse spontaneous metastasis models that neoadjuvant immunotherapy and surgery was su
Externí odkaz:
https://doaj.org/article/540ebb5775024460ba49e196c3a62cae
Autor:
Jing Liu, Elisa A. Rozeman, Jake S. O’Donnell, Stacey Allen, Lorenzo Fanchi, Mark J. Smyth, Christian U. Blank, Michele W.L. Teng
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
New clinical trials are now evaluating the efficacy of neoadjuvant immunotherapy in the context of primary tumor surgery. Using the orthotopic 4T1.2 mouse model of spontaneously metastatic mammary cancer, we have shown that neoadjuvant immunotherapy
Externí odkaz:
https://doaj.org/article/9cb1a065726841ffad39b3e29814631f
Autor:
Heidi Harjunpää, Stephen J. Blake, Elizabeth Ahern, Stacey Allen, Jing Liu, Juming Yan, Viviana Lutzky, Kazuyoshi Takeda, Amy Roman Aguilera, Camille Guillerey, Deepak Mittal, Xian Yang Li, William C. Dougall, Mark J. Smyth, Michele W. L. Teng
Publikováno v:
OncoImmunology, Vol 7, Iss 7 (2018)
Multiple non-redundant immunosuppressive pathways co-exist in the tumor microenvironment and their co-targeting can increase clinical responses. Indeed, concurrent blockade of CTLA-4 and PD-1 in patients with advanced melanoma increased clinical resp
Externí odkaz:
https://doaj.org/article/3d0f9472a6d948b5a0735e8f9ef889dd
Autor:
Elizabeth Ahern, Heidi Harjunpää, Jake S. O'Donnell, Stacey Allen, William C. Dougall, Michele W. L. Teng, Mark J. Smyth
Publikováno v:
OncoImmunology, Vol 7, Iss 6 (2018)
Receptor activator of NF-κB ligand (RANKL) and its receptor RANK, are members of the tumor necrosis factor and receptor superfamilies, respectively. Antibodies targeting RANKL have recently been evaluated in combination with anti-CTLA4 in case repor
Externí odkaz:
https://doaj.org/article/ab711549ba3a4d8cad8103589d9e54ee
Autor:
Michele W.L. Teng, Mark J. Smyth, Daniel J. Cua, Jing Liu, Kazuyoshi Takeda, Heidi Harjunpää, Xian-Yang Li, Dipti Vijayan, Stacey Allen, Juming Yan
Tumor-induced immunosuppression is mediated through various mechanisms including engagement of immune checkpoint receptors on effector cells, function of immunoregulatory cells such as regulatory T cells and myeloid-derived suppressor cells, and depl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f682ccdac006324378d6aeaa536038f
https://doi.org/10.1158/2326-6066.c.6548966.v1
https://doi.org/10.1158/2326-6066.c.6548966.v1
Autor:
Michele W.L. Teng, Mark J. Smyth, Antiopi Varelias, Alexandra J. Corbett, Zhenjun Chen, Bronwyn S. Meehan, David P. Fairlie, Ligong Liu, Jeffrey Y.W. Mak, Indrajit Das, Elizabeth McDonald, Stacey Allen, Juming Yan
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that require MHC class I–related protein 1 (MR1) for their development. The role of MAIT cells in cancer is unclear, and to date no study has evaluated these cells in vivo in this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e7eab58af12b54673fad8c067c2ba51
https://doi.org/10.1158/2159-8290.c.6547925.v1
https://doi.org/10.1158/2159-8290.c.6547925.v1
Autor:
Mark J. Smyth, Michele W.L. Teng, Günter Bernhardt, Engin Gurlevik, Florian Kühnel, Kazuyoshi Takeda, Marco Colonna, Ludovic Martinet, Lucas Ferrari de Andrade, Viviana P. Lutzky, John J. Miles, Amelia Roman Aguilera, Deepak Mittal, Michelle C.R. Yong, Stacey Allen, Jing Liu, Kimberley Stannard, Stephen J. Blake
Supplementary Figure S5. Anti-CD96 combines with anti-CTLA4 or anti-PD1 to enhance survival following challenge with experimental lung metastases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676a1aace18dfc07dd750284489b704a
https://doi.org/10.1158/2159-8290.22531005
https://doi.org/10.1158/2159-8290.22531005
Autor:
Michele W.L. Teng, Mark J. Smyth, Stacey Allen, Jake S. O'Donnell, Arabella Young, Kazuyoshi Takeda, Shin Foong Ngiow, Heidi Harjunpää, Michelle C.R. Yong, Stephen J. Blake, Jing Liu
Supplemental Table S1. List of antibodies used for flow cytometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf71fbeb4c6015d20522b99aa908476
https://doi.org/10.1158/2159-8290.22531272
https://doi.org/10.1158/2159-8290.22531272
Autor:
Michele W.L. Teng, Mark J. Smyth, Antiopi Varelias, Alexandra J. Corbett, Zhenjun Chen, Bronwyn S. Meehan, David P. Fairlie, Ligong Liu, Jeffrey Y.W. Mak, Indrajit Das, Elizabeth McDonald, Stacey Allen, Juming Yan
Supplementary text and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593011345c53d1cee8c65f66a9ac6728
https://doi.org/10.1158/2159-8290.22535711.v1
https://doi.org/10.1158/2159-8290.22535711.v1
Autor:
Mark J. Smyth, Michele W.L. Teng, Günter Bernhardt, Engin Gurlevik, Florian Kühnel, Kazuyoshi Takeda, Marco Colonna, Ludovic Martinet, Lucas Ferrari de Andrade, Viviana P. Lutzky, John J. Miles, Amelia Roman Aguilera, Deepak Mittal, Michelle C.R. Yong, Stacey Allen, Jing Liu, Kimberley Stannard, Stephen J. Blake
Supplementary Methods, Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1234e557cb451bb4934bd80e37ea3eeb
https://doi.org/10.1158/2159-8290.22530993.v1
https://doi.org/10.1158/2159-8290.22530993.v1