Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Stacey A. Snyder"'
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 17(4)
Essentials Many mediators increase tissue factor (TF) expression in a wide variety of cell types. The only known example of TF downregulation is by pericytes during wound healing angiogenesis. Downregulation of TF mRNA and protein in cultured pericyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6218657da9f867f65aeaf245a764a280
https://pubmed.ncbi.nlm.nih.gov/30698330
https://pubmed.ncbi.nlm.nih.gov/30698330
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Tissue factor (TF) is a transmembrane receptor for factor VII/VIIa that plays a central role in hemostasis and angiogenesis. While TF is generally upregulated in pathologic conditions, we have reported that TF is downregulated in pericytes around ves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e19d0b351a170ef23f24eed26dfac969
https://doi.org/10.1161/atvb.36.suppl_1.377
https://doi.org/10.1161/atvb.36.suppl_1.377
Autor:
Lan Lan, Chen Jiang, Jen-Tsan Ashley Chi, James R. MacFall, Chelsea D. Landon, Diane Renee Fels, Donald E. Thrall, Mark W. Dewhirst, Linda M. McCall, Benjamin L. Viglianti, Stacey A. Snyder, Marlene L. Hauck
Publikováno v:
Clinical Cancer Research. 17:2549-2560
Purpose: While hyperthermia is an effective adjuvant treatment to radiotherapy, we do not completely understand the nature of the response heterogeneity. Experimental Design: We performed gene expression analysis of 22 spontaneous canine sarcomas bef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68cb4c9f3d6ac54dfa3a9db61f5d497
https://doi.org/10.1158/1078-0432.ccr-10-2583
https://doi.org/10.1158/1078-0432.ccr-10-2583
Publikováno v:
Mammalian Genome. 21:577-582
The prognosis given for canine soft tissue sarcomas (STSs) is based primarily on histopathologic grade. The decision to administer adjuvant chemotherapy is difficult since less than half of patients with high-grade STSs develop metastatic disease. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc33d04ef9b4999823dcf362a788aa2f
https://doi.org/10.1007/s00335-010-9298-y
https://doi.org/10.1007/s00335-010-9298-y
Publikováno v:
Veterinary Pathology. 48:482-485
Stringently controlled in vitro experiments are a necessary part of translational research. Cell lines are useful for exploring the underlying biology of cancer. Very few canine soft tissue sarcoma cell lines exist. This report describes the establis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd01d9e135a65fbd1f37f8633f202724
https://doi.org/10.1177/0300985810383871
https://doi.org/10.1177/0300985810383871
Publikováno v:
Veterinary and Comparative Oncology. 6:213-223
Human oncology has clearly demonstrated the existence of hypoxic tumours and the problematic nature of those tumours. Hypoxia is a significant problem in the treatment of all types of solid tumours and a common reason for treatment failure. Hypoxia i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d217fd263c139f658d868288870941
https://doi.org/10.1111/j.1476-5829.2008.00163.x
https://doi.org/10.1111/j.1476-5829.2008.00163.x
Autor:
Zahid N. Rabbani, John P. Kirkpatrick, Kimberly L. Blackwell, Zeljko Vujaskovic, Siqing Shan, Matthew E. Hardee, Stacey A. Snyder, Mark W. Dewhirst
Publikováno v:
British Journal of Cancer
Tumour hypoxia has been shown to increase mutation rate, angiogenesis, and metastatic potential, and decrease response to conventional therapeutics. Improved tumour oxygenation should translate into increased treatment response. Exogenous recombinant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b4ef2da600ffa5bcad1009ea5b4eb5
https://doi.org/10.1038/sj.bjc.6602846
https://doi.org/10.1038/sj.bjc.6602846
Autor:
Mark W. Dewhirst, Rachel A. Richardson, R. D. Braun, Pierre Sonveaux, Timothy J. McMahon, Andrew M. Kaz, John R. Pawloski, Gillian M. Tozer, Jonathan S. Stamler, Stacey A. Snyder, Joseph Bonaventura, L. Isabel Cárdenas-Navia
Publikováno v:
Circulation Research. 96:1119-1126
In erythrocytes, S -nitrosohemoglobin (SNO-Hb) arises from S -nitrosylation of oxygenated hemoglobin (Hb). It has been shown that SNO-Hb behaves as a nitric oxide (NO) donor at low oxygen tensions. This property, in combination with oxygen transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2639128b3324ab344bb2906525516f3
https://doi.org/10.1161/01.res.0000168740.04986.a7
https://doi.org/10.1161/01.res.0000168740.04986.a7
Autor:
Vlayka Liotcheva, Gloria Broadwater, Rex C. Bentley, Mark W. Dewhirst, Kimberly L. Blackwell, S. Anderson, Alan D. Proia, Gregory J. Riggins, Lyndsay Harris, Stacey A. Snyder, Jim Vredenburgh, Anita Lal
Publikováno v:
Clinical Cancer Research. 10:4083-4088
Purpose: This study investigated the connection among HER-2 gene amplification, HER-2 protein expression, and markers of tumor angiogenesis and oxygenation in patients with operable, invasive breast tumors. Experimental Design: From 1988 to 1995, 425
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0727b88202ed653d6e7a3ccc5dc18f9
https://doi.org/10.1158/1078-0432.ccr-03-0695
https://doi.org/10.1158/1078-0432.ccr-03-0695
Autor:
William Novotny, Charles S. Greenberg, Kimberly L. Blackwell, Herbert Hurwitz, Mark W. Dewhirst, Grazyna Lieberman, Stacey A. Snyder
Publikováno v:
Cancer. 101:77-82
BACKGROUND Fibrin formation is required for tumor angiogenesis, metastasis, and invasion. D-dimer, a fibrin degradation product, is produced when crosslinked fibrin is degraded by plasmin. The current study prospectively examined D-dimer levels in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e4505949afabe63abc369a0a2f58b6c
https://doi.org/10.1002/cncr.20336
https://doi.org/10.1002/cncr.20336