Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stacey A. Rimkus"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3109-3119 (2020)
Neuroinflammation is a major pathophysiological feature of traumatic brain injury (TBI). Early and persistent activation of innate immune response signaling pathways by primary injuries is associated with secondary cellular injuries that cause TBI ou
Externí odkaz:
https://doaj.org/article/aed6e503161e45e4ae633224d31bde57
Autor:
Rebeccah J Katzenberger, Stanislava Chtarbanova, Stacey A Rimkus, Julie A Fischer, Gulpreet Kaur, Jocelyn M Seppala, Laura C Swanson, Jocelyn E Zajac, Barry Ganetzky, David A Wassarman
Publikováno v:
eLife, Vol 4 (2015)
Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Unfavorable TBI outcomes result from primary mechanical injuries to the brain and ensuing secondary non-mechanical injuries that are not limited to the brain. Our genome
Externí odkaz:
https://doaj.org/article/52f4dc41ba39414d82588d0fce68ce8a
Autor:
Kassi L. Crocker, Stacey A. Rimkus, Khailee Marischuk, Jerry C.P. Yin, Grace Boekhoff-Falk, Hong Zhou
Publikováno v:
Genetics. 219
Neurodegenerative diseases such as Alzheimer’s and Parkinson’s currently affect ∼25 million people worldwide. The global incidence of traumatic brain injury (TBI) is estimated at ∼70 million/year. Both neurodegenerative diseases and TBI remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b891aa7ccd3561439f7ff9afc42cc91d
https://doi.org/10.1093/genetics/iyab092
https://doi.org/10.1093/genetics/iyab092
Autor:
Kassi L. Crocker, Khailee Marischuk, Hong Zhou, Stacey A. Rimkus, Jerry C.P. Yin, Grace Boekhoff-Falk
The location of nucleosomes in chromatin significantly impacts many biological processes including DNA replication, repair and gene expression. A number of techniques have been developed for mapping nucleosome locations in chromatin including MN-Seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e80884273ed717c5de528e7dfa4849
https://doi.org/10.1101/2020.01.16.908640
https://doi.org/10.1101/2020.01.16.908640
Autor:
David A. Wassarman, Stacey A. Rimkus
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 1, p e0190821 (2018)
PLoS ONE, Vol 13, Iss 1, p e0190821 (2018)
Ataxia-telangiectasia (A-T) is a neurodegenerative disease caused by mutation of the A-T mutated (ATM) gene. ATM encodes a protein kinase that is activated by DNA damage and phosphorylates many proteins, including those involved in DNA repair, cell c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4759b95afec1799fd9f81350fe4aab8
https://pubmed.ncbi.nlm.nih.gov/29338042
https://pubmed.ncbi.nlm.nih.gov/29338042
Autor:
Gulpreet Kaur, Laura C Swanson, Jocelyn M Seppala, Stanislava Chtarbanova, Jocelyn E Zajac, David A. Wassarman, Julie A. Fischer, Barry Ganetzky, Stacey A. Rimkus, Rebeccah J. Katzenberger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74e3e31a1974be20bb717d9c6db7c5df
https://doi.org/10.7554/elife.04790.026
https://doi.org/10.7554/elife.04790.026
Autor:
Jennifer M. Vrtis, Ryan Woodyer, Stacey A. Rimkus, Wilfred A. van der Donk, Heather A. Relyea
Publikováno v:
Biochemistry. 44:6640-6649
Phosphite dehydrogenase (PTDH) catalyzes the NAD-dependent oxidation of phosphite to phosphate, a reaction that is 15 kcal/mol exergonic. The enzyme belongs to the family of D-hydroxy acid dehydrogenases. Five other family members that were analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4d43182be2408df32aa4eebfa4b022
https://doi.org/10.1021/bi047640p
https://doi.org/10.1021/bi047640p
Autor:
Laura C Swanson, Julie A. Fischer, Barry Ganetzky, Gulpreet Kaur, Stacey A. Rimkus, Stanislava Chtarbanova, David A. Wassarman, Rebeccah J. Katzenberger, Jocelyn E Zajac, Jocelyn M Seppala
Publikováno v:
eLife
eLife, Vol 4 (2015)
eLife, Vol 4 (2015)
Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Unfavorable TBI outcomes result from primary mechanical injuries to the brain and ensuing secondary non-mechanical injuries that are not limited to the brain. Our genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a262981192deb42ae5181e66d8e4ad52
https://pubmed.ncbi.nlm.nih.gov/25742603
https://pubmed.ncbi.nlm.nih.gov/25742603
To investigate the mechanistic basis for central nervous system (CNS) neurodegeneration in the disease ataxia–telangiectasia (A-T), we analyzed flies mutant for the causative gene A-T mutated ( ATM ). ATM encodes a protein kinase that functions to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a82d52647a6657efa62987ae49d9a3f
https://europepmc.org/articles/PMC3306708/
https://europepmc.org/articles/PMC3306708/
Autor:
David A. Wassarman, Gerald E. Dodson, Rebeccah J. Katzenberger, Stacey A. Rimkus, Anthony T. Trinh, Randal S. Tibbetts
Publikováno v:
Genesdevelopment. 22(9)
Mutations in ATM (Ataxia telangiectasia mutated) result in Ataxia telangiectasia (A-T), a disorder characterized by progressive neurodegeneration. Despite advances in understanding how ATM signals cell cycle arrest, DNA repair, and apoptosis in respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a2f3d93fcb2864c922651e79408eed
https://pubmed.ncbi.nlm.nih.gov/18408079
https://pubmed.ncbi.nlm.nih.gov/18408079