Zobrazeno 1 - 10
of 1 704
pro vyhledávání: '"St. Croix"'
Autor:
Kazuhiro Yamada, Claudette St. Croix, Donna B. Stolz, Yulia Y. Tyurina, Vladimir A. Tyurin, Laura R. Bradley, Alexander A. Kapralov, Yanhan Deng, Xiuxia Zhou, Qi Wei, Bo Liao, Nobuhiko Fukuda, Mara Sullivan, John Trudeau, Anuradha Ray, Valerian E. Kagan, Jinming Zhao, Sally E. Wenzel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract A stable mitochondrial pool is crucial for healthy cell function and survival. Altered redox biology can adversely affect mitochondria through induction of a variety of cell death and survival pathways, yet the understanding of mitochondria
Externí odkaz:
https://doaj.org/article/1c733dcdc5e7478d914aed5291e53938
Autor:
Kate Runacres, Jill Garner, Chanelle Goulet, Farah Wissanji, Rhonda St Croix, Kate Marsden, Lucie Filteau, Guylaine Lefebvre, Sofia Valanci-Aroesty
Publikováno v:
Journal of CME, Vol 13, Iss 1 (2024)
Continuous professional development (CPD) is crucial for physicians to maintain and enhance their skills. In response to the changing context of CPD and health care, this study applied a design thinking approach to transform and modernise the Royal C
Externí odkaz:
https://doaj.org/article/3889f336a4334c1ba3ba9b17ffc4a543
Autor:
Leonard Frisbie, Catherine Pressimone, Emma Dyer, Roja Baruwal, Geyon Garcia, Claudette St. Croix, Simon Watkins, Michael Calderone, Grace Gorecki, Zaineb Javed, Huda I. Atiya, Nadine Hempel, Alexander Pearson, Lan G. Coffman
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114551- (2024)
Summary: Ovarian cancer is characterized by early metastatic spread. This study demonstrates that carcinoma-associated mesenchymal stromal cells (CA-MSCs) enhance metastasis by increasing tumor cell heterogeneity through mitochondrial donation. CA-MS
Externí odkaz:
https://doaj.org/article/fadc5372690c419fb9d343cb2641fa43
Autor:
Frisbie, Leonard, Pressimone, Catherine, Dyer, Emma, Baruwal, Roja, Garcia, Geyon, St. Croix, Claudette, Watkins, Simon, Calderone, Michael, Gorecki, Grace, Javed, Zaineb, Atiya, Huda I., Hempel, Nadine, Pearson, Alexander, Coffman, Lan G.
Publikováno v:
In Cell Reports 27 August 2024 43(8)
Autor:
Torres Chavez, Alejandro G., McKenna, Mary K., Balasubramanian, Kishore, Riffle, Lisa, Patel, Nimit L., Kalen, Joseph D., St. Croix, Brad, Leen, Ann M., Bajgain, Pradip
Publikováno v:
In Molecular Therapy: Oncology 21 March 2024 32(1)
Autor:
Dan Li, Ruixue Wang, Tianyuzhou Liang, Hua Ren, Chaelee Park, Chin-Hsien Tai, Weiming Ni, Jing Zhou, Sean Mackay, Elijah Edmondson, Javed Khan, Brad St Croix, Mitchell Ho
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Rational design of chimeric antigen receptor T (CAR-T) cells based on the recognition of antigenic epitopes capable of evoking the most potent CAR activation is an important objective in optimizing immune therapy. In solid tumors, the B7-H3
Externí odkaz:
https://doaj.org/article/d633e7c59ca149f7b0f28503297c8880
Autor:
Alejandro G. Torres Chavez, Mary K. McKenna, Kishore Balasubramanian, Lisa Riffle, Nimit L. Patel, Joseph D. Kalen, Brad St. Croix, Ann M. Leen, Pradip Bajgain
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200763- (2024)
Bioluminescence imaging is a well-established platform for evaluating engineered cell therapies in preclinical studies. However, despite the discovery of new luciferases and substrates, optimal combinations to simultaneously monitor two cell populati
Externí odkaz:
https://doaj.org/article/558925265e4f40398a632e9e5d4e52d4
Autor:
R. Undamatla, O. G. Fagunloye, J. Chen, L. R. Edmunds, A. Murali, A. Mills, B. Xie, M. M. Pangburn, I. Sipula, G. Gibson, C. St. Croix, M. J. Jurczak
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of pathologies that includes steatosis, steatohepatitis (NASH) and fibrosis and is strongly associated with insulin resistance and type 2 diabetes. Changes in mitochondrial func
Externí odkaz:
https://doaj.org/article/aa7fe506c5da4b44ab0be9759318a6ae
Autor:
Feng, Yang, Lee, Jaewon, Yang, Liping, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Edupuganti, Veera V. Shivaji R., Hsu, Kuo-Sheng, Dower, Christopher, Yu, Guojun, So, Daeho, Bajgain, Pradip, Zhu, Zhongyu, Dimitrov, Dimiter S., Patel, Nimit L., Robinson, Christina M., Difilippantonio, Simone, Dyba, Marzena, Corbel, Amanda, Basuli, Falguni, Swenson, Rolf E., Kalen, Joseph D., Suthe, Sreedhar Reddy, Hussain, Myer, Italia, James S., Souders, Colby A., Gao, Ling, Schnermann, Martin J., St. Croix, Brad
Publikováno v:
In Cell Reports 26 December 2023 42(12)