Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stéphanie Zdanov"'
Publikováno v:
Biogerontology. 10:291-298
Cyclooxygenase-2 and release of prostaglandin E2 are up-regulated in replicative senescence of dermal and prostate fibroblasts and in H2O2-induced premature senescence of IMR-90 lung fibroblasts expressing the catalytic subunit of telomerase. Inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5142380272453f78f8f367cc40fa1072
https://doi.org/10.1007/s10522-008-9204-0
https://doi.org/10.1007/s10522-008-9204-0
Autor:
Karo Gosselin, Olivier Toussaint, Chantal Vercamer, Fazia Chelli, Corinne Abbadie, David Bernard, Florence Debacq-Chainiaux, Sébastien Martien, Stéphanie Zdanov
Publikováno v:
Experimental Cell Research. 313(14):3046-3056
Cyclooxygenase-2 (COX-2) is an inducible enzyme of the prostaglandin biosynthesis pathway. It is involved in many stress responses, and its activity can produce oxidative damage, suggesting it could participate in senescence. In this study, COX-2 exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27836c3f5ef91c4e5574e26dc7b7f1ee
https://researchportal.unamur.be/en/publications/b2a09fc2-7ec8-45c4-8e49-f0cd1e394499
https://researchportal.unamur.be/en/publications/b2a09fc2-7ec8-45c4-8e49-f0cd1e394499
Publikováno v:
Annals of the New York Academy of Sciences. 1100:316-322
Premature senescence of IMR-90 human diploid fibroblasts (HDFs) expressing telomerase was induced by exposure to sublethal concentration of H(2)O(2), with appearance of several biomarkers of cellular senescence like enlarged cell shape, senescence-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a653fca2f0b279f4b88e2294f547fcbe
https://doi.org/10.1196/annals.1395.034
https://doi.org/10.1196/annals.1395.034
Publikováno v:
FEBS Letters. 580:6455-6463
Premature senescence of IMR-90 human diploid fibroblasts expressing telomerase (hTERT) establishes after exposure to an acute sublethal concentration of H2O2. We showed herein that p38MAPK was phosphorylated after exposure of IMR-90 hTERT cells to H2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c95082ebf9f3f3cb54a19882cc385a6
https://doi.org/10.1016/j.febslet.2006.10.064
https://doi.org/10.1016/j.febslet.2006.10.064
Publikováno v:
Annals of the New York Academy of Sciences. 1067:210-216
Premature senescence of human fibroblasts is established after exposure to an acute sublethal concentration of H(2)O(2). Overexpression of transforming growth factor-beta1 (TGF-beta1) was shown to be responsible for the appearance of the biomarkers o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acff47a0c886d4d99936c305593690d
https://doi.org/10.1196/annals.1354.025
https://doi.org/10.1196/annals.1354.025
Autor:
Jean François Dierick, João Pedro de Magalhães, Véronique Royer, Olivier Toussaint, Stéphanie Zdanov, José Remacle, Thierry Pascal, Christophe Frippiat, Florence Chainiaux
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 34:1415-1429
The Hayflick limit-senescence of proliferative cell types-is a fundamental feature of proliferative cells in vitro. Various human proliferative cell types exposed in vitro to many types of subcytotoxic stresses undergo stress-induced premature senesc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70a8da11dac5ea10f5c8336142f63e7b
https://doi.org/10.1016/s1357-2725(02)00034-1
https://doi.org/10.1016/s1357-2725(02)00034-1
Autor:
Jean-François Dierick, Christophe Frippiat, Joao Pedro Magalhacs, José Remacle, Stéphanie Zdanov, Véronique Royer, Olivier Toussaint, Florence Chainiaux, Thierry Pascal
Publikováno v:
Biogerontology. 3:13-17
The similarities between the biomarkers of stress-induced premature senescence and replicative senescence are reviewed. The possibility of existence of `molecular scars', i.e. long-term changes observed after subcytotoxic stress and not observed in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccca6951d75f74b8a1b129fcdf3723c0
https://doi.org/10.1023/a:1015226524335
https://doi.org/10.1023/a:1015226524335
Autor:
Stéphanie Zdanov, Christophe Frippiat, José Remacle, Olivier Toussaint, Patrick Dumont, Thierry Pascal, Jean-François Dierick, Florence Chainiaux, João Pedro de Magalhães
Publikováno v:
The Scientific World Journal
The Scientific World Journal, Vol 2, Pp 230-247 (2002)
The Scientific World Journal, Vol 2, Pp 230-247 (2002)
No consensus exists so far on the definition of cellular senescence. The narrowest definition of senescence is irreversible growth arrest triggered by telomere shortening counting cell generations (definition 1). Other authors gave an enlarged functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41984383fda7e7c5f973afa428ae2d02
https://doi.org/10.1100/tsw.2002.100
https://doi.org/10.1100/tsw.2002.100
Autor:
Christophe Frippiat, Qin M. Chen, Joao Padro Magalhaes, José Remacle, Olivier Toussaint, Stéphanie Zdanov
Publikováno v:
Journal of Biological Chemistry. 276:2531-2537
Stress-induced premature senescence (SIPS) is induced 3 days after exposure of human diploid fibroblasts to subcytotoxic oxidative stress with H(2)O(2), with appearance of several biomarkers of replicative senescence. In this work, we show that trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3100e41132f1c35242cf105ab3a2d7e7
https://doi.org/10.1074/jbc.m006809200
https://doi.org/10.1074/jbc.m006809200
Publikováno v:
Cell Cycle. 9:1675-1677
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e450b97b9af94106cd2eee5a01311a
https://doi.org/10.4161/cc.9.9.11650
https://doi.org/10.4161/cc.9.9.11650