Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Stéphanie Philippot"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 24-35 (2023)
Ligand-based drug design methods are thought to require large experimental datasets to become useful for virtual screening. In this work, we propose a computational strategy to design novel inhibitors of coronavirus main protease, Mpro. The pipeline
Externí odkaz:
https://doaj.org/article/74aede9c10164905ad429c3d3436a749
Autor:
Dhouha Dallali, Jawhar Fakhfakh, Cédric Paris, Nissaf Aoiadni, Stéphanie Philippot, Arnaud Risler, Mihayl Varbanov, Noureddine Allouche
Publikováno v:
Plants, Vol 13, Iss 6, p 909 (2024)
The current study aimed to investigate the chemical composition, antioxidant, antibacterial, and cytotoxic properties of three extracts (hexane, dichloromethane, and methanol) from Cynoglossum tubiflorus. The composition of the methanolic extract was
Externí odkaz:
https://doaj.org/article/88b020e5574245918e21779ea952be44
Publikováno v:
Viruses, Vol 15, Iss 6, p 1342 (2023)
The abietane diterpene (+)-ferruginol (1), like other natural and semisynthetic abietanes, is distinguished for its interesting pharmacological properties such as antimicrobial activity, including antiviral. In this study, selected C18-functionalized
Externí odkaz:
https://doaj.org/article/ebebb60a7b6a404cb606574bd8c7b201
Autor:
Abdirahman Elmi, Fatouma Mohamed Abdoul-Latif, Rosella Spina, François Dupire, Stéphanie Philippot, Champy Marie-France, Hugues Jacobs, Dominique Laurain-Mattar
Publikováno v:
Molecules, Vol 26, Iss 10, p 3046 (2021)
For the first time, the study of the antioxidant activity, the characterization of the phytoconstituants, and the evaluation of in vitro and in vivo toxicity of A. djiboutiensis leave and latex are performed. The antioxidant activity of both latex (A
Externí odkaz:
https://doaj.org/article/a3cc8133074148b69c3706b333545c6a
Autor:
Afra Khiralla, Rosella Spina, Mihayl Varbanov, Stéphanie Philippot, Pascal Lemiere, Sophie Slezack-Deschaumes, Philippe André, Ietidal Mohamed, Sakina Mohamed Yagi, Dominique Laurain-Mattar
Publikováno v:
Microorganisms, Vol 8, Iss 9, p 1353 (2020)
An endophytic fungus isolated from Vernonia amygdalina, a medicinal plant from Sudan, was taxonomically characterized as Curvularia papendorfii. Ethyl acetate crude extract of C. papendorfii revealed an important antiviral effect against two viral pa
Externí odkaz:
https://doaj.org/article/01ff266880d141ab8289acc086da8bec
Autor:
Abdirahman Elmi, Rosella Spina, Arnaud Risler, Stéphanie Philippot, Ali Mérito, Raphaël E. Duval, Fatouma Mohamed Abdoul-latif, Dominique Laurain-Mattar
Publikováno v:
Molecules, Vol 25, Iss 10, p 2392 (2020)
Water extract of Acacia seyal bark is used traditionally by the population in Djibouti for its anti-infectious activity. The evaluation of in vitro antibacterial, antioxidant activities and cytotoxicity as well as chemical characterization of Acacia
Externí odkaz:
https://doaj.org/article/a6eeda7a14f6438c844e88d33812a085
Autor:
Inès Thabti, Quentin Albert, Stéphanie Philippot, François Dupire, Brenda Westerhuis, Stéphane Fontanay, Arnaud Risler, Thomas Kassab, Walid Elfalleh, Ali Aferchichi, Mihayl Varbanov
Publikováno v:
Molecules, Vol 25, Iss 8, p 1876 (2020)
(1) Background: Viral respiratory infections cause life-threatening diseases in millions of people worldwide every year. Human coronavirus and several picornaviruses are responsible for worldwide epidemic outbreaks, thus representing a heavy burden t
Externí odkaz:
https://doaj.org/article/c9c2c670ac8544f49ceefa547bad30de
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 38:24-35
Ligand-based drug design methods are thought to require large experimental datasets to become useful for virtual screening. In this work, we propose a computational strategy to design novel inhibitors of coronavirus main protease, Mpro. The pipeline
Publikováno v:
Viruses; Volume 15; Issue 6; Pages: 1342
The abietane diterpene (+)-ferruginol (1), like other natural and semisynthetic abietanes, is distinguished for its interesting pharmacological properties such as antimicrobial activity, including antiviral. In this study, selected C18-functionalized
Autor:
Raphaël E. Duval, Claus Jacob, Komlan Batawila, Frederic Nana, Gilbert Kirsch, Patrick Chaimbault, Stéphanie Philippot, Yérim Mbagnick Diop, Stéphane Fontanay, Koffi Akpagana, Nassifatou Koko Tittikpina, Véronique Vaillant, Louis P. Sandjo
Publikováno v:
Phytochemistry Letters
Phytochemistry Letters, Elsevier, 2019, 32, pp.110-114. ⟨10.1016/j.phytol.2019.05.013⟩
Phytochemistry Letters, Elsevier, 2019, 32, pp.110-114. ⟨10.1016/j.phytol.2019.05.013⟩
The popular use of Pterocarpus erinaceus as antimicrobial prompted us to study the antifungal properties of its bark, leaves and roots against Candida albicans, Aspergillus fumigatus, and Aspergillus niger. Thus, the broth microdilution method was us