Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stéphanie Lambel"'
Autor:
Juan J. Vaquero, Alain Pierré, Ramón Alajarín, Nuria Sánchez, Julio Alvarez-Builla, Stéphane Léonce, Daniel Henri Caignard, Alberto Fontana, Enrique J. Benito, Stéphanie Lambel-Giraudet, M.Justina Martı́n
Publikováno v:
e_Buah Biblioteca Digital Universidad de Alcalá
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Several new pyridazino[1',6':1,2]pyrido[3,4-b]indol-5-inium derivatives were synthesised from beta-carboline derivatives and their cytotoxic activity and effect on the cell cycle were evaluated against L1210 cancer cells.
Autor:
Michel H. J. Koch, Sylvie Michel, François Tillequin, Stéphanie Lambel, Alain Pierré, John A. Hickman, Bruno Pfeiffer, Ghanem Atassi, Valérie Pérez, Delphine Peyroulan, Stéphane Léonce
Publikováno v:
Molecular Pharmacology. 60:1383-1391
S23906-1 is a diester derivative of 1,2-dihydrobenzo[b]acronycine with an unknown mechanism of action. This cytotoxic compound was 20-fold more potent than acronycine in inhibiting the proliferation of six tumor cell lines. Using a clonogenic assay o
Autor:
Stéphanie Lambel, Pierre Colson, Michelle Prudhomme, Claude Houssier, Christian Bailly, Aline Voldoire, Martine Sancelme, Stéphane Léonce
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:357-365
Glycosylated indolocarbazoles related to the antibiotic rebeccamycin represent an important series of antitumor drugs. In the course of structure–activity relationship studies, we report the synthesis of two new derivatives containing an indolo[2,3
Publikováno v:
Tetrahedron Letters. 42:8297-8299
6′,7′-Dihydrokeramamine C 7d and analogues have been synthesised and evaluated for their cytotoxicity. Compound 7f in which the azacycloundecane ring has been substituted by a dihexylamino unit showed increasing biological activity.
Publikováno v:
ChemInform. 33
Autor:
Pierre Renard, Stéphanie Lambel, Alain Pierré, Vincent Lisowski, Cécile Enguehard, Sylvain Rault, Ghanem Atassi, Jean-Charles Lancelot, Daniel-Henri Caignard, Stéphane Léonce
Publikováno v:
Bioorganicmedicinal chemistry letters. 11(16)
Structure–activity relationship studies of a new series of tripentones (thieno[2,3-b]pyrrolizin-8-ones), led us to prepare several derivatives with antiproliferative activities. The most promising 3-(3-hydroxy-4-methoxyphenyl)thieno[2,3-b]pyrrolizi