Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stéphanie Duguez"'
Autor:
Apostolos Malatras, Ioannis Michalopoulos, Stéphanie Duguez, Gillian Butler-Browne, Simone Spuler, William J. Duddy
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-16 (2020)
Abstract Background High-throughput transcriptomics measures mRNA levels for thousands of genes in a biological sample. Most gene expression studies aim to identify genes that are differentially expressed between different biological conditions, such
Externí odkaz:
https://doaj.org/article/1619693adebe4dba901c15d444cd92d4
Autor:
Vasileios L. Zogopoulos, Apostolos Malatras, Konstantinos Kyriakidis, Chrysanthi Charalampous, Evanthia A. Makrygianni, Stéphanie Duguez, Marianna A. Koutsi, Marialena Pouliou, Christos Vasileiou, William J. Duddy, Marios Agelopoulos, George P. Chrousos, Vassiliki A. Iconomidou, Ioannis Michalopoulos
Publikováno v:
Cells, Vol 12, Iss 3, p 388 (2023)
Genes with similar expression patterns in a set of diverse samples may be considered coexpressed. Human Gene Coexpression Analysis 2.0 (HGCA2.0) is a webtool which studies the global coexpression landscape of human genes. The website is based on the
Externí odkaz:
https://doaj.org/article/5baa97564d3b4d308b3a022df8935b6e
Autor:
Anne Bigot, William J. Duddy, Zamalou G. Ouandaogo, Elisa Negroni, Virginie Mariot, Svetlana Ghimbovschi, Brennan Harmon, Aurore Wielgosik, Camille Loiseau, Joe Devaney, Julie Dumonceaux, Gillian Butler-Browne, Vincent Mouly, Stéphanie Duguez
Publikováno v:
Cell Reports, Vol 13, Iss 6, Pp 1172-1182 (2015)
The molecular mechanisms by which aging affects stem cell number and function are poorly understood. Murine data have implicated cellular senescence in the loss of muscle stem cells with aging. Here, using human cells and by carrying out experiments
Externí odkaz:
https://doaj.org/article/7f96e260906c4120a8bf5bab9bf674c7
Autor:
Laura Le Gall, William J. Duddy, Cecile Martinat, Virginie Mariot, Owen Connolly, Vanessa Milla, Ekene Anakor, Zamalou G. Ouandaogo, Stephanie Millecamps, Jeanne Lainé, Udaya Geetha Vijayakumar, Susan Knoblach, Cedric Raoul, Olivier Lucas, Jean Philippe Loeffler, Peter Bede, Anthony Behin, Helene Blasco, Gaelle Bruneteau, Maria Del Mar Amador, David Devos, Alexandre Henriques, Adele Hesters, Lucette Lacomblez, Pascal Laforet, Timothee Langlet, Pascal Leblanc, Nadine Le Forestier, Thierry Maisonobe, Vincent Meininger, Laura Robelin, Francois Salachas, Tanya Stojkovic, Giorgia Querin, Julie Dumonceaux, Gillian Butler Browne, Jose‐Luis González De Aguilar, Stephanie Duguez, Pierre Francois Pradat
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 1385-1402 (2022)
Abstract Background The cause of the motor neuron (MN) death that drives terminal pathology in amyotrophic lateral sclerosis (ALS) remains unknown, and it is thought that the cellular environment of the MN may play a key role in MN survival. Several
Externí odkaz:
https://doaj.org/article/261a53bffa414819a14cb82060834ea9
Autor:
Lydie, Laure, Nathalie, Danièle, Laurence, Suel, Sylvie, Marchand, Sophie, Aubert, Nathalie, Bourg, Carinne, Roudaut, Stéphanie, Duguez, Marc, Bartoli, Isabelle, Richard
Publikováno v:
The FEBS journal. 277(20)
A multiprotein complex encompassing a transcription regulator, cardiac ankyrin repeat protein (CARP), and the calpain 3 protease was identified in the N2A elastic region of the giant sarcomeric protein titin. The present study aimed to investigate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ae5203892765f47b74203bd4acafcaf
https://pubmed.ncbi.nlm.nih.gov/20860623
https://pubmed.ncbi.nlm.nih.gov/20860623
Autor:
Gavin McCluskey, Karen E. Morrison, Colette Donaghy, John McConville, Mark O. McCarron, Ferghal McVerry, William Duddy, Stephanie Duguez
Publikováno v:
Life, Vol 13, Iss 6, p 1301 (2023)
Neurofilament levels are elevated in many neurodegenerative diseases and have shown promise as diagnostic and prognostic biomarkers in Amyotrophic Lateral Sclerosis (ALS), the most common form of Motor Neuron Disease (MND). This study assesses serum
Externí odkaz:
https://doaj.org/article/bb9b2c9371864173857717ee6d92326f
Autor:
Laura Le Gall, Zamalou Gisele Ouandaogo, Ekene Anakor, Owen Connolly, Gillian Butler Browne, Jeanne Laine, William Duddy, Stephanie Duguez
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Skeletal muscle is increasingly considered an endocrine organ secreting myokines and extracellular vesicles (exosomes and microvesicles), which can affect physiological changes with an impact on different pathological conditions, including r
Externí odkaz:
https://doaj.org/article/57028613469c4a7893bb8b2477d40d99
Autor:
Gavin McCluskey, Karen E. Morrison, Colette Donaghy, Frederique Rene, William Duddy, Stephanie Duguez
Publikováno v:
Life, Vol 13, Iss 1, p 121 (2022)
Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disease and is the most common adult motor neuron disease. The disease pathogenesis is complex with the perturbation of multiple pathways proposed, including mitochondrial dysfunction,
Externí odkaz:
https://doaj.org/article/a303a635ec844d9f957bd64378531d0e
Publikováno v:
Skeletal Muscle, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Background The approach of building large collections of gene sets and then systematically testing hypotheses across these collections is a powerful tool in functional genomics, both in the pathway analysis of omics data and to uncover the p
Externí odkaz:
https://doaj.org/article/7a4e6862ba894ab1a425bf737b6b3a41
Autor:
Ekene Anakor, Vanessa Milla, Owen Connolly, Cecile Martinat, Pierre Francois Pradat, Julie Dumonceaux, William Duddy, Stephanie Duguez
Publikováno v:
Cells, Vol 11, Iss 5, p 845 (2022)
Extracellular vesicles can mediate communication between tissues, affecting the physiological conditions of recipient cells. They are increasingly investigated in Amyotrophic Lateral Sclerosis, the most common form of Motor Neurone Disease, as transp
Externí odkaz:
https://doaj.org/article/16dc8e24421e4a67b8c0dec65565feee