Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stéphanie Desvergnes"'
Autor:
Maciej Dabrowski, Michel Therisod, Racha Daher, Laurent Salmon, Stéphanie Courtiol-Legourd, Stéphanie Desvergnes
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:1511-1520
In the design of inhibitors of phosphosugar metabolizing enzymes and receptors with therapeutic interest, malonate has been reported in a number of cases as a good and hydrolytically-stable surrogate of the phosphate group, since both functions are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180a05d78c222e030674b75060955e90
https://doi.org/10.1016/j.bmc.2011.12.050
https://doi.org/10.1016/j.bmc.2011.12.050
Publikováno v:
The Journal of Organic Chemistry. 70:1459-1462
[reaction: see text] A concise total synthesis of (+)-hyacinthacine A(2), a polyhydroxylated pyrrolizidine alkaloid, is described using our recently discovered inversion of the C-N bond polarity in nitrones. In the key step, the diastereoselective re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e805ce8c86166845bb5c3191244cd8
https://doi.org/10.1021/jo048237r
https://doi.org/10.1021/jo048237r
Autor:
Daan M. F. van Aalten, D.E. Blair, Ian M. Eggleston, Christina L. Rush, Adel F. M. Ibrahim, Alexander W. Schüttelkopf, Ramon Hurtado-Guerrero, Stéphanie Desvergnes
SummaryNatural products are often large, synthetically intractable molecules, yet frequently offer surprising inroads into previously unexplored chemical space for enzyme inhibitors. Argifin is a cyclic pentapeptide that was originally isolated as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630e6a4278d0eb1617495b711a28c226
https://europepmc.org/articles/PMC3518266/
https://europepmc.org/articles/PMC3518266/
Publikováno v:
ChemInform. 39
A general method to prepare a new class of carbohydrate-derived, enantiomerically pure polyhydroxypyrroline N-oxides from their alkoxy (protected) derivatives is presented. Boron trichloride is shown to cleave efficiently benzyl ethers and ketals wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e45e040c8e893c0723528ce9f6d327ff
https://doi.org/10.1002/chin.200848186
https://doi.org/10.1002/chin.200848186
Publikováno v:
Organic letters. 10(14)
A general method to prepare a new class of carbohydrate-derived, enantiomerically pure polyhydroxypyrroline N-oxides from their alkoxy (protected) derivatives is presented. Boron trichloride is shown to cleave efficiently benzyl ethers and ketals wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf07c8474fc0e584bfe86110d81939e3
https://pubmed.ncbi.nlm.nih.gov/18570375
https://pubmed.ncbi.nlm.nih.gov/18570375
Autor:
Olivier R. Martin, Valérie Desvergnes, Stéphanie Desvergnes, Sandrine Py, Kenji Itoh, Hung-wen Liu
Publikováno v:
Bioorganicmedicinal chemistry. 15(19)
The synthesis of 1-C-substituted 1,4-dideoxy-1,4-imino-D-galactitols involving nitrone umpolung is described. The SmI(2)-induced key coupling proved highly stereoselective in favor of the beta-C-substituted products bearing a three-carbon chain at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f506c7ea1247a97bcee0406631c341b9
https://pubmed.ncbi.nlm.nih.gov/17662609
https://pubmed.ncbi.nlm.nih.gov/17662609
Novel Polyhydroxylated Cyclic Nitrones and N-Hydroxypyrrolidines through BCl3-Mediated Deprotection.
Publikováno v:
Organic Letters; May2008, Vol. 10 Issue 14, p2967-2970, 4p