Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stéphanie Chevrier"'
Autor:
Vincent Jannin, Fiona McCartney, Cédric Miolane, Nicolas Ritter, Frédéric Demarne, Delyan R. Hristov, Hakime Boulghobra, David J. Brayden, Yann Chavant, Stéphanie Chevrier
Publikováno v:
Journal of Controlled Release. 310:115-126
Labrasol® ALF (Labrasol®), is a non-ionic surfactant excipient primarily used as a solubilising agent. It was investigated here as an intestinal permeation enhancer in isolated rat colonic mucosae in Ussing chamber and in rat in situ intestinal ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822bd424debef6c700927a888beff363
https://doi.org/10.1016/j.jconrel.2019.08.008
https://doi.org/10.1016/j.jconrel.2019.08.008
Autor:
Cédric Miolane, Frédéric Demarne, Vincent Jannin, Lucia Blas, Stéphanie Chevrier, Denis Spitzer
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 111
Objective To evaluate the digestibility of Solid Lipid Nanoparticles (SLN) of glyceryl dibehenate prepared either with surfactants by ultrasonication or without surfactant by spray-flash evaporation. Methods SLN of glyceryl dibehenate (Compritol® 88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603eee502507867501d6c12ffb2b9299
https://pubmed.ncbi.nlm.nih.gov/28966096
https://pubmed.ncbi.nlm.nih.gov/28966096
Autor:
Brian Dewar, Stephanie Chevrier, Julie De Meulemeester, Mark Fedyk, Rosendo Rodriguez, Simon Kitto, Raphael Saginur, Michel Shamy
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Introduction Equipoise, generally defined as uncertainty about the relative effects of the treatments being compared in a trial, is frequently referenced as an ethical standard for the conduct of randomized clinical trials. However, it seems
Externí odkaz:
https://doaj.org/article/919522d9f43a41539889c865e7a587e8
Autor:
Stéphanie Chevrier, Frédéric Demarne, Vincent Jannin, Yann Chavant, Christophe Voutsinas, Cristina Bonferoni, Eleonora Dellera
Publikováno v:
Drug Development and Industrial Pharmacy. 41:1582-1588
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLC) are lipid nanocarriers aimed to the delivery of drugs characterized by a low bioavailability, such as poorly water-soluble drugs and peptides or proteins. The oral administratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bcc6c1ed60f77e6a8cdab142e5fff5
https://doi.org/10.3109/03639045.2014.972412
https://doi.org/10.3109/03639045.2014.972412
Autor:
A. Malmazet, V Bérard, C. Andrès, Y. Chavant, Frédéric Demarne, Vincent Jannin, Stéphanie Chevrier
Publikováno v:
Journal of Drug Delivery Science and Technology. 23:181-185
Solid-phase lubricants are routinely used in tablet manufacturing to reduce friction during the densification and ejection phases. However, two main challenges are commonly observed: a) poor blending of the lubricant with the other components; b) inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7917442f77529ffee707f323f462e34e
https://doi.org/10.1016/s1773-2247(13)50027-x
https://doi.org/10.1016/s1773-2247(13)50027-x
Autor:
Stéphanie Chevrier, Sylvie Fernandez, Vincent Jannin, Bruno Mahler, Nicolas Ritter, Frédéric Carrière, Frédéric Demarne
Publikováno v:
Pharmaceutical Research. 26:1901-1910
Labrasol and Gelucire 44/14 are defined admixtures of acylglycerols and PEG esters which are substrates for digestive lipases.We investigated their in vitro gastrointestinal lipolysis to understand which compounds are, after digestion, responsible fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996200a9a6e547cb8e540395e9280326
https://doi.org/10.1007/s11095-009-9906-2
https://doi.org/10.1007/s11095-009-9906-2
Autor:
Camille Dumont, Stéphanie Chevrier, Yann Chavant, Vincent Jannin, Frédéric Demarne, Silvia Belotti, Matthieu Michenaud
Publikováno v:
International journal of pharmaceutics. 495(1)
Lipid-based formulations can be effective drug delivery systems for poorly water-soluble chemical entities, provided they are designed with careful selection of the excipients, based on their role in the delivery system and in relation to drug proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224b7a3550f9505180243a3f9e69574e
https://pubmed.ncbi.nlm.nih.gov/26364710
https://pubmed.ncbi.nlm.nih.gov/26364710
Autor:
Sylvie Fernandez, Yann Chavant, Frédéric Demarne, Vincent Jannin, Stéphanie Chevrier, Frédéric Carrière
Publikováno v:
Pharmaceutical research. 30(12)
Labrasol(®) is a self-emulsifying excipient used to improve the oral bioavailability of poorly water-soluble drugs. It is a mixture of acylglycerols and PEG esters, these compounds being substrates for digestive lipases. The characterization of Labr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47200b645bc534aa91273b6b78e049ff
https://pubmed.ncbi.nlm.nih.gov/23636839
https://pubmed.ncbi.nlm.nih.gov/23636839
Autor:
Brian Dewar, Mark Fedyk, Michel Shamy, Raphael Saginur, Lucas Jurkovic, Stephanie Chevrier, Rosendo Rodriguez
Publikováno v:
BMJ Open, Vol 9, Iss 7 (2019)
Introduction Randomised controlled trials (RCTs) are widely viewed to generate the most reliable medical knowledge. However, RCTs are not always scientifically necessary and therefore not always ethical. Unfortunately, it is not clear when an RCT is
Externí odkaz:
https://doaj.org/article/3cbc19aa1c194d37b03bd8efc98d07e9