Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stéphanie Chanteux"'
Autor:
Ivan Perrot, Henri-Alexandre Michaud, Marc Giraudon-Paoli, Séverine Augier, Aurélie Docquier, Laurent Gros, Rachel Courtois, Cécile Déjou, Diana Jecko, Ondine Becquart, Hélène Rispaud-Blanc, Laurent Gauthier, Benjamin Rossi, Stéphanie Chanteux, Nicolas Gourdin, Beatrice Amigues, Alain Roussel, Armand Bensussan, Jean-François Eliaou, Jérémy Bastid, François Romagné, Yannis Morel, Emilie Narni-Mancinelli, Eric Vivier, Carine Paturel, Nathalie Bonnefoy
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2411-2425.e9 (2019)
Summary: Immune checkpoint inhibitors have revolutionized cancer treatment. However, many cancers are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting tumor evasion. The production of adenosine via the seq
Externí odkaz:
https://doaj.org/article/5587ee70bc8c4270948f7103cc944bcd
Autor:
Hélène Rispaud-Blanc, Jean-François Eliaou, Cécile Dejou, Rachel Courtois, Béatrice Amigues, Emilie Narni-Mancinelli, Nathalie Bonnefoy, Jérémy Bastid, Armand Bensussan, Marc Giraudon-Paoli, Aurélie Docquier, François Romagné, O. Becquart, Carine Paturel, Ivan Perrot, Benjamin Rossi, Yannis Morel, Laurent Gauthier, Henri-Alexandre Michaud, Laurent Gros, Eric Vivier, Nicolas Gourdin, Alain Roussel, Diana Jecko, Stéphanie Chanteux, Severine Augier
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2019, 27 (8), pp.2411-2425. ⟨10.1016/j.celrep.2019.04.091⟩
Cell Reports, Vol 27, Iss 8, Pp 2411-2425.e9 (2019)
Cell Reports, Elsevier (Cell Press), 2019, 27 (8), pp.2411+. ⟨10.1016/j.celrep.2019.04.091⟩
Cell Reports, 2019, 27 (8), pp.2411-2425. ⟨10.1016/j.celrep.2019.04.091⟩
Cell Reports, Elsevier Inc, 2019, 27 (8), pp.2411-2425. ⟨10.1016/j.celrep.2019.04.091⟩
Cell Reports, Vol 27, Iss 8, Pp 2411-2425.e9 (2019)
Cell Reports, Elsevier (Cell Press), 2019, 27 (8), pp.2411+. ⟨10.1016/j.celrep.2019.04.091⟩
Cell Reports, 2019, 27 (8), pp.2411-2425. ⟨10.1016/j.celrep.2019.04.091⟩
Summary: Immune checkpoint inhibitors have revolutionized cancer treatment. However, many cancers are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting tumor evasion. The production of adenosine via the seq
Autor:
Jacqueline Shaw, Demin Li, Laurent Gauthier, Simon Kollnberger, Zhiyong Zhang, Julie C. Mitchell, Kaitlin Marquardt, Benjamin Rossi, Stéphanie Chanteux, Hiroko Hatano
Publikováno v:
The Journal of Immunology. 194:1591-1601
We proposed that the killer cell Ig-like receptor KIR3DL2 binding more strongly to HLA-B27 (B27) β2-microglobulin free H chain (FHC) dimers than other HLA–class I molecules regulates lymphocyte function in arthritis and infection. We compared the
Autor:
Anne Marie-Cardine, Nicolas Viaud, Nicolas Thonnart, Armand Bensussan, Laurent Gauthier, Martine Bagot, Stéphanie Chanteux, Carine Paturel, Hélène Sicard, Mathieu Blery, Rachel Joly, Cécile Bonnafous, Benjamin Rossi
Publikováno v:
Cancer Research. 74:6060-6070
Advanced cutaneous T-cell lymphoma (CTCL) remains an unmet medical need, which lacks effective targeted therapies. In this study, we report the development of IPH4102, a humanized monoclonal antibody that targets the immune receptor KIR3DL2, which is
Autor:
Paul Ricaut, Aurélie Docquier, Ariane Morel, Marc Giraudon Paoli, Diana Jecko, Frédéric Bosco, Caroline Denis, Romain Remark, Cécile Bonnafous, Laurent Gauthier, Carine Paturel, Jérémy Bastid, Benjamin Rossi, Nicolas Gourdin, Stéphanie Chanteux, Severine Augier, Nathalie Bonnefoy, Rachel Courtois, Marilyne Royannez Blemont, Cyril Perrier, Agnès Represa, Maryline Salin Agu, Yannis Morel, Ivan Perrot, Stephane Delahaye, Marion Gaudin
Publikováno v:
Cancer Research. 78:2718-2718
Within the tumor microenvironment, adenosine causes immune suppression and dysregulation of immune cell infiltrates resulting in tumor spreading. Adenosine accumulation results from the hydrolysis of extracellular immunoactivating ATP and ADP into AM
Autor:
Olivier Benac, Stéphanie Cornen, Carine Paturel, Mélody Ors, Aude Le Roy, Laurent Gauthier, Marion Gaudin, Ivan Perrot, Hélène Rispaud Blanc, Caroline Soulas, Benjamin Rossi, Yannis Morel, Stéphanie Chanteux
Publikováno v:
Cancer Research. 78:2713-2713
Siglec-9 is a MHC class I-independent inhibitory receptor expressed on NK and myeloid cells (including dendritic cells, monocytes and neutrophils). Its ligands are sialic acid-containing carbohydrates which are over-expressed on various tumor types c
Autor:
Céline Rodriguez, Marc Giraudon Paoli, Hélène Rispaud Blanc, Yannis Morel, Laurent Gauthier, Carine Paturel, Nicolas Gourdin, Christophe Caux, Ivan Perrot, Stéphanie Chanteux, Severine Augier, Christine Menetrier Caux, Marilyne Royannez Blemont
Publikováno v:
Cancer Research. 76:2344-2344
CD73 (NT5E) is a cell membrane ectoenzyme of the NTPDase family that plays a major role in the conversion of AMP into Adenosine (Ado). Within the tumor microenvironment, accumulation of Ado causes immune suppression and dysregulation of immune cell i