Výsledky vyhledávání - "Stéphanie Arnould"

Akademický článek

The Transcription Factor E4F1 Coordinates CHK1-Dependent Checkpoint and Mitochondrial Functions

Autor: Geneviève Rodier, Olivier Kirsh, Martín Baraibar, Thibault Houlès, Matthieu Lacroix, Hélène Delpech, Elodie Hatchi, Stéphanie Arnould, Dany Severac, Emeric Dubois, Julie Caramel, Eric Julien, Bertrand Friguet, Laurent Le Cam, Claude Sardet

Publikováno v: Cell Reports, Vol 11, Iss 2, Pp 220-233 (2015)

Recent data support the notion that a group of key transcriptional regulators involved in tumorigenesis, including MYC, p53, E2F1, and BMI1, share an intriguing capacity to simultaneously regulate metabolism and cell cycle. Here, we show that another

Externí odkaz: https://doaj.org/article/750ec7fa7c584a56a4679e3138ac001f

Zobrazit plný text záznamu

Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition

Autor: Stéphanie Arnould, Laura Ermellino, Jean-Philippe Herbeuval, Claude Sardet, Rodolphe Alves de Sousa, Nicolas Pietrancosta, Anna Hovhannisyan, Sébastien Nisole, Olivier Diaz, Simon Hayek, Pierre-Olivier Vidalain, Julien Dairou, Gagik Melikyan, Nassima Bekaddour, Vincent Lotteau, Enzo Tramontano

Publikováno v: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 186, pp.111855. ⟨10.1016/j.ejmech.2019.111855⟩
European Journal of Medicinal Chemistry, 2020, 186, pp.111855. ⟨10.1016/j.ejmech.2019.111855⟩

International audience; There is an increasing interest in the field of cancer therapy for small compounds targeting pyrimidine biosynthesis, and in particular dihydroorotate dehydrogenase (DHODH), the fourth enzyme of this metabolic pathway. Three a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165cc82b4bd18dd1566d0212c17f0b74
https://hal.archives-ouvertes.fr/hal-02372490/file/P1788-Manuscript-Revised-Final.pdf

Zobrazit plný text záznamu

Structures of Nahuoic Acids B–E Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment and Evidence for the Inhibition of the Histone Methyl Transferase SETD8 in Human Cancer Cells by Nahuoic Acid A

Autor: Teatulohi Matainaho, Doralyn S. Dalisay, Eric Julien, Cholpisut Tantapakul, David E. Williams, Stéphanie Arnould, Fanny Izard, Raymond J. Andersen, Wisanu Maneerat

Publikováno v: Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2016, 81 (4), pp.1324-1332. ⟨10.1021/acs.joc.5b02569⟩

International audience; Nahuoic acids A-E (1-5) have been isolated from laboratory cultures of a Streptomyces sp. obtained from a tropical marine sediment. The structures of the new polyketides 2-5 were elucidated by analysis of spectroscopic data of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca37d6b6abf939f4748c679f4008082
https://doi.org/10.1021/acs.joc.5b02569

Zobrazit plný text záznamu

Antiproliferative and antioxidant activities of wild Boletales mushrooms from France

Autor: Françoise Fons, Frédéric Boudard, Stéphanie Arnould, Caroline Guzman, Manon Vitou, Sylvie Morel, Patrick Poucheret, Sylvie Rapior

Publikováno v: International Journal of Medicinal Mushrooms
International Journal of Medicinal Mushrooms, Begell House, 2018, 20 (1), pp.13-29. ⟨10.1615/IntJMedMushrooms.2018025329⟩

International audience; We selected edible and inedible mushrooms growing in the Mediterranean area of France to screen their biological activity: Caloboletus calopus, Rubroboletus lupinus, R. pulchrotinctus, R. satanas, Gyroporus castaneus, Suillus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8644b6d82d06241bf19e8721584c8a6e
https://hal.umontpellier.fr/hal-02196149

Zobrazit plný text záznamu

Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition

Autor: Stéphanie Arnould, Geneviève Rodier, Jean Noel, Charlene Berthet, Simon Lachambre, Charles Vincent, Pierre-Olivier Vidalain, Florence Bernex, Marta Jarlier, Nelly Pirot, Yoan Buscail, Charles Theillet, Claude Sardet, Yoann Delorme, Yves L. Janin, Gisèle Matar, Hélène Delpech

Publikováno v: Oncotarget
Oncotarget, 2017, 8 (56), pp.95206-95222. ⟨10.18632/oncotarget.19199⟩
Oncotarget, Impact journals, 2017, 8 (56), pp.95206-95222. ⟨10.18632/oncotarget.19199⟩

International audience; Reduction in nucleotide pools through the inhibition of mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) has been demonstrated to effectively reduce cancer cell proliferation and tumour growth. The current study sough

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b502789eabeeaa08564f8079d4ae12
https://hal.umontpellier.fr/hal-02291385

Zobrazit plný text záznamu

ChemInform Abstract: Structures of Nahuoic Acids B-E Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment and Evidence for the Inhibition of the Histone Methyl Transferase SETD8 in Human Cancer Cells by Nahuoic Acid A

Autor: Stéphanie Arnould, Cholpisut Tantapakul, Eric Julien, Raymond J. Andersen, Fanny Izard, Wisanu Maneerat, Doralyn S. Dalisay, David E. Williams, Teatulohi Matainaho

Publikováno v: ChemInform. 47

Nahuoic acids A-E (1-5) have been isolated from laboratory cultures of a Streptomyces sp. obtained from a tropical marine sediment. The structures of the new polyketides 2-5 were elucidated by analysis of spectroscopic data of the natural products an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b334ceda810f4b5a8e35cf12df10035b
https://doi.org/10.1002/chin.201628242

Zobrazit plný text záznamu

Combination of oxaliplatin and irinotecan on human colon cancer cell lines: activity in vitro and in vivo

Autor: Isabelle Hennebelle, Sylvie Guichard, Roland Bugat, Stéphanie Arnould, Pierre Canal

Publikováno v: Anti-Cancer Drugs. 12:741-751

The in vitro and in vivo combination of oxaliplatin and irinotecan was investigated in a panel of four human colon cancer cell lines and their counterpart xenografts. In vitro and in vivo experiments demonstrated a synergistic or additive interaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942c3483255fc1cce6ab3d6a668e796b
https://doi.org/10.1097/00001813-200110000-00006

Zobrazit plný text záznamu

Isoflavones and the prevention of breast and prostate cancer: New perspectives opened by nutrigenomics

Autor: Augustin Scalbert, Stéphanie Arnould, Claudine Manach, Claudia Steiner

Publikováno v: British Journal of Nutrition
British Journal of Nutrition, Cambridge University Press (CUP), 2008, 99 (E-S1), pp.ES78-108. ⟨10.1017/S0007114508965788⟩

Epidemiological evidence together with preclinical data from animal andin vitrostudies strongly support a correlation between soy isoflavone consumption and protection towards breast and prostate cancers. The biological processes modulated by isoflav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fac481cb91ac725eed5b909293fb4ff
https://hal.inrae.fr/hal-02656597

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání