Evolution of Matrix Gla and Bone Gla Protein Genes in Jawed Vertebrates

Autor: Nicolas Leurs, Camille Martinand-Mari, Stéphanie Ventéo, Tatjana Haitina, Mélanie Debiais-Thibaud

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

Matrix Gla protein (Mgp) and bone Gla protein (Bgp) are vitamin-K dependent proteins that bind calcium in their γ-carboxylated versions in mammals. They are recognized as positive (Bgp) or negative (Mgp and Bgp) regulators of biomineralization in a

Externí odkaz: https://doaj.org/article/7c47be13e30b46dea9f34ff3b1e81bb6

Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors

Autor: Stéphanie Ventéo, Simon Desiderio, Pauline Cabochette, Alexandre Deslys, Patrick Carroll, Alexandre Pattyn

Publikováno v: Cell Reports, Vol 29, Iss 10, Pp 2953-2960.e2 (2019)

Summary: Functionally distinct classes of dorsal root ganglia (DRG) somatosensory neurons arise from neural crest cells (NCCs) in two successive phases of differentiation assumed to be respectively and independently controlled by the proneural genes

Externí odkaz: https://doaj.org/article/02debae61c2a459b97292f1183d08986

Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death

Autor: Fabrice Bouilloux, Jérôme Thireau, Stéphanie Ventéo, Charlotte Farah, Sarah Karam, Yves Dauvilliers, Jean Valmier, Neal G Copeland, Nancy A Jenkins, Sylvain Richard, Frédéric Marmigère

Publikováno v: eLife, Vol 5 (2016)

Although cardio-vascular incidents and sudden cardiac death (SCD) are among the leading causes of premature death in the general population, the origins remain unidentified in many cases. Genome-wide association studies have identified Meis1 as a ris

Externí odkaz: https://doaj.org/article/303724f029024de2813c23d49f828d6c

CaMKK-CaMK1a, a new post-traumatic signalling pathway induced in mouse somatosensory neurons.

Autor: Lucie Elzière, Chamroeun Sar, Stéphanie Ventéo, Steeve Bourane, Sylvie Puech, Corinne Sonrier, Hassan Boukhadaoui, Agnès Fichard, Alexandre Pattyn, Jean Valmier, Patrick Carroll, Ilana Méchaly

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e97736 (2014)

Neurons innervating peripheral tissues display complex responses to peripheral nerve injury. These include the activation and suppression of a variety of signalling pathways that together influence regenerative growth and result in more or less succe

Externí odkaz: https://doaj.org/article/c7945b53ad3147d290f4233dd9e44934

Cytotoxic CD8 + T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons

Autor: Nicolas Degauque, Claire Soulard, Frédérique Scamps, David Laplaud, Attila Gergely Végh, Céline Salsac, Margot Libralato, Cédric Raoul, Emmanuelle Coque, Stéphanie Ventéo, Csilla Gergely, José Boucraut, Gabriel Espinosa-Carrasco, Roxane Crabé, Béla Varga, Alexandre Brodovitch, Thierry Vincent, Anaïs Virenque, Javier Hernandez, Julie K. Fierle, Marion Cadoux

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (6), pp.2312-2317. ⟨10.1073/pnas.1815961116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (6), pp.2312-2317. ⟨10.1073/pnas.1815961116⟩
Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 6, pp. 2312-2317

Adaptive immune response is part of the dynamic changes that accompany motoneuron loss in amyotrophic lateral sclerosis (ALS). CD4 + T cells that regulate a protective immunity during the neurodegenerative process have received the most attention. CD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b74d69287c1970bf57c427665e4698
https://www.hal.inserm.fr/inserm-03171288