Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Stéphane Thore"'
Autor:
Stéphane Thore, Finaritra Raoelijaona, Vincent Talenton, Sébastien Fribourg, Cameron D. Mackereth
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
Eukaryotic pre-mRNA is processed by a large multiprotein complex to accurately cleave the 3′ end, and to catalyse the addition of the poly(A) tail. Within this cleavage and polyadenylation specificity factor (CPSF) machinery, the CPSF73/CPSF3 endon
Externí odkaz:
https://doaj.org/article/e26fea51e1d9470e8319e60396c52d99
Publikováno v:
FEBS Open Bio, Vol 8, Iss 10, Pp 1605-1614 (2018)
Rrp5 is an essential factor during the ribosome biogenesis process. The protein contains a series of 12 S1 RNA‐binding domains followed by a TetratricoPeptide Repeat (TPR) domain. In the past, several studies aiming at defining the function of the
Externí odkaz:
https://doaj.org/article/1ed9ddb724e74a11a6ea3c6429143d22
Autor:
Asun Monfort, Giulio Di Minin, Andreas Postlmayr, Remo Freimann, Fabiana Arieti, Stéphane Thore, Anton Wutz
Publikováno v:
Cell Reports, Vol 12, Iss 4, Pp 554-561 (2015)
In mammals, the noncoding Xist RNA triggers transcriptional silencing of one of the two X chromosomes in female cells. Here, we report a genetic screen for silencing factors in X chromosome inactivation using haploid mouse embryonic stem cells (ESCs)
Externí odkaz:
https://doaj.org/article/ec33956c6e2f4fc98f8bb5284b2faad3
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94610 (2014)
The most abundant of the modified nucleosides, and once considered as the "fifth" nucleotide in RNA, is pseudouridine, which results from the action of pseudouridine synthases. Recently, the mammalian pseudouridine synthase 1 (hPus1p) has been report
Externí odkaz:
https://doaj.org/article/b77fe52de2cf4b4cafd706ce10ca8ee1
Autor:
Taisuke Nishimura, Guillaume Molinard, Tom J Petty, Larissa Broger, Caroline Gabus, Thanos D Halazonetis, Stéphane Thore, Jerzy Paszkowski
Publikováno v:
PLoS Genetics, Vol 8, Iss 2, p e1002484 (2012)
Shifts between epigenetic states of transcriptional activity are typically correlated with changes in epigenetic marks. However, exceptions to this rule suggest the existence of additional, as yet uncharacterized, layers of epigenetic regulation. MOM
Externí odkaz:
https://doaj.org/article/d95746e77a524befa0493f0280375480
Publikováno v:
Biomolecular NMR Assignments. 17:43-48
The initial pre-mRNA transcript in eukaryotes is processed by a large multi-protein complex in order to correctly cleave the 3’ end, and to subsequently add the polyadenosine tail. This cleavage and polyadenylation specificity factor (CPSF) is comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33ecebb4922db106fa1f74ca422d44b
https://doi.org/10.1007/s12104-023-10118-6
https://doi.org/10.1007/s12104-023-10118-6
Mitochondria are essential organelles carrying their own genetic information which require specific gene expression processes. The leucine rich pentatricopeptide protein (LRPPRC) and its partner the SRA stem-loop interacting RNA binding protein (SLIR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96750444dad4411ef569bbf1d260a126
Publikováno v:
RNA biology
RNA biology, Taylor & Francis, In press, 15 (9), pp.1174-1180. ⟨10.1080/15476286.2018.1517013⟩
RNA biology, Taylor & Francis, In press, 15 (9), pp.1174-1180. ⟨10.1080/15476286.2018.1517013⟩
International audience; Ribosome biogenesis requires a variety of trans-acting factors in order to produce functional ribosomal subunits. In human cells, the complex formed by the proteins hNob1 and hPno1 is crucial to the site 3 cleavage occurring a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9cda162f815c3d756db1e13b9d7556
https://doi.org/10.1080/15476286.2018.1517013
https://doi.org/10.1080/15476286.2018.1517013
Autor:
Aurore Guédin, Liliya A. Yatsunyk, Samir Armane, Linda Yingqi Lin, Jean-Louis Mergny, Stéphane Thore, Laurent Lacroix
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2018, 46 (10), pp.5297-5307. ⟨10.1093/nar/gky290⟩
'Nucleic Acids Research ', vol: 46, pages: 5297-5307 (2018)
Nucleic Acids Research, Oxford University Press, 2018, 46 (10), pp.5297-5307. ⟨10.1093/nar/gky290⟩
'Nucleic Acids Research ', vol: 46, pages: 5297-5307 (2018)
Guanine-rich DNA has the potential to fold into non-canonical G-quadruplex (G4) structures. Analysis of the genome of the social amoeba Dictyostelium discoideum indicates a low number of sequences with G4-forming potential (249–1055). Therefore, D.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa85ed8dc516dd508ef77697dc1e7238
https://doi.org/10.1093/nar/gky290
https://doi.org/10.1093/nar/gky290
Autor:
Sébastien Fribourg, Stéphane Thore
Publikováno v:
Biochimie
Biochimie, Elsevier, 2019, 164, pp.105-110. ⟨10.1016/j.biochi.2019.03.016⟩
Biochimie, 2019, 164, pp.105-110. ⟨10.1016/j.biochi.2019.03.016⟩
Biochimie, Elsevier, 2019, 164, pp.105-110. ⟨10.1016/j.biochi.2019.03.016⟩
Biochimie, 2019, 164, pp.105-110. ⟨10.1016/j.biochi.2019.03.016⟩
Pre-mRNA 3'-end maturation is achieved by a mechanism requiring four different protein complexes assembled from approximately twenty factors. A global understanding of this essential process is still missing due to the inability to structurally chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc73be56d28fc4d7590dfc90e7fe1f5f
https://hal.archives-ouvertes.fr/hal-02472477
https://hal.archives-ouvertes.fr/hal-02472477