Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stéphane Legras"'
Autor:
René Adam, Jean-Paul Thièry, I Blazsek, Michel Reynes, Aurora Anjo, Sylvie Marion, Jean Louis Misset, Stéphane Legras
Publikováno v:
Hepatology. 29:1406-1417
Primary hepatocellular carcinoma (HCC) is probably one of the most common fatal forms of liver cancer. We have established permanent cell lines from diethylnitrosamine/phenobarbital induced primary rat liver carcinomas to study new anticancer therapi
Autor:
J. P. Marie, Hanneke C. Kluin-Nelemans, Florence Smadja-Joffe, Stéphane Legras, Claude Jasmin, Ursula Günthert, F. Curt, Stephen J. Proctor, Snezhana Oliferenko, R. Stauder
Publikováno v:
Europe PubMed Central
CD44 is a ubiquitous cell-surface glycoprotein that displays many variant isoforms (CD44v) generated by alternative splicing of exons 2v to 10v. The expression of variant isoforms is highly restricted and correlated with specific processes, such as l
Autor:
Stéphane Legras, Florence Smadja-Joffe, Jean-Pierre Levesque, Denis Clay, Kohji Morimoto, Claude Jasmin, Rachida Sihem Charrad, Caroline Le Bousse
Publikováno v:
Blood. 89:1905-1914
Adhesive interactions between CD34+ hematopoietic progenitor cells (HPC) and bone marrow stroma are crucial for normal hematopoiesis, yet their molecular bases are still poorly elucidated. We have investigated whether cell surface proteoglycan CD44 c
Publikováno v:
International Journal of Biological Macromolecules. 14:97-99
N-desulphated heparin, partially N-acylated on average with three oleoyl chains per molecule, inhibits the amidolytic activity of plasmin (IC50 16 nM) and urokinase (IC50 10mM) when assayed on N-p-tosyl-Gly-Pro-Lys-4-nitroanilide and benzoyl-Ala-Gly-
Autor:
C LeBousseKerdiles, N Girard, Stéphane Legras, Florence Smadja-Joffe, F Bloget, Claude Jasmin, B Delpech, Jean-Pierre Levesque, Y. Li, Denis Clay, K Morimoto
Publikováno v:
Leukemialymphoma. 21(5-6)
The CD44 cell surface molecule has been shown to be the principal cell surface receptor for hyaluronan (or hyaluronic acid), a glycosaminoglycan component of marrow extracellular matrix. However, its affinity for hyaluronan is not constitutive, since