Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Stéphane L Benoit"'
Autor:
Faith C Blum, Heidi Q Hu, Stephanie L Servetas, Stéphane L Benoit, Robert J Maier, Michael J Maroney, D Scott Merrell
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183260 (2017)
The nickel-containing enzymes of Helicobacter pylori, urease and hydrogenase, are essential for efficient colonization in the human stomach. The insertion of nickel into urease and hydrogenase is mediated by the accessory protein HypA. HypA contains
Externí odkaz:
https://doaj.org/article/aef9b851d9c14782b2b027eabdf72ce1
Autor:
Stéphane L. Benoit, Robert J. Maier
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Campylobacter concisus, an emerging pathogen found throughout the human oral-gastrointestinal tract, is able to grow under microaerobic or anaerobic conditions; in the latter case, N- or S-oxides could be used as terminal electron acceptors
Externí odkaz:
https://doaj.org/article/e391e41baa534550b13184609cee49c2
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Iron–sulfur (Fe–S) proteins play essential roles in all living organisms. The gastric pathogen Helicobacter pylori relies exclusively on the NIF system for biosynthesis and delivery of Fe–S clusters. Previously characterized components
Externí odkaz:
https://doaj.org/article/c9d9b12e159948309bc5d5996a5b71ed
Autor:
Stéphane L. Benoit, Robert J. Maier
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract One of the hallmarks of the most common neurodegenerative disease, Alzheimer’s disease (AD), is the extracellular deposition and aggregation of Amyloid Beta (Aβ)-peptides in the brain. Previous studies have shown that select metal ions, m
Externí odkaz:
https://doaj.org/article/d0ec3b635d684dfc8f53839f454dbc95
Autor:
Stéphane L. Benoit, Alan A. Schmalstig, John Glushka, Susan E. Maier, Arthur S. Edison, Robert J. Maier
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract The nickel (Ni)-specific chelator dimethylglyoxime (DMG) has been used for many years to detect, quantitate or decrease Ni levels in various environments. Addition of DMG at millimolar levels has a bacteriostatic effect on some enteric patho
Externí odkaz:
https://doaj.org/article/ba948ee605c447938767fdd68a6d105c
Autor:
Bingchen Yu, Manjusha Roy Choudhury, Xiaoxiao Yang, Stéphane L. Benoit, Edroyal Womack, Kristin Van Mouwerik Lyles, Atanu Acharya, Arvind Kumar, Ce Yang, Anna Pavlova, Mengyuan Zhu, Zhengnan Yuan, James C. Gumbart, David W. Boykin, Robert J. Maier, Zehava Eichenbaum, Binghe Wang
Publikováno v:
ACS Infectious Diseases. 8:1491-1508
The rapid and persistent emergence of drug-resistant bacteria poses a looming public health crisis. The possible task of developing new sets of antibiotics to replenish the existing ones is daunting to say the least. Searching for adjuvants that rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adadf5703cc696bb0d78aef3323554d7
https://doi.org/10.1021/acsinfecdis.2c00121
https://doi.org/10.1021/acsinfecdis.2c00121
Autor:
Ge Wang, Judith Romero-Gallo, Stéphane L. Benoit, M. Blanca Piazuelo, Ricardo L. Dominguez, Douglas R. Morgan, Richard M. Peek, Robert J. Maier
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
ABSTRACT A known virulence factor of Helicobacter pylori that augments gastric cancer risk is the CagA cytotoxin. A carcinogenic derivative strain, 7.13, that has a greater ability to translocate CagA exhibits much higher hydrogenase activity than it
Externí odkaz:
https://doaj.org/article/0bd3243815314c17a2bcffe12026516b
Autor:
Stéphane L. Benoit, Robert J. Maier
Publikováno v:
mBio, Vol 5, Iss 1 (2014)
ABSTRACT The twin-arginine translocation (Tat) system, needed to transport folded proteins across biological membranes, has not been characterized in the gastric pathogen Helicobacter pylori. Analysis of all H. pylori genome sequences available thus
Externí odkaz:
https://doaj.org/article/c2d69e96736646008566a65b320bdea8
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Iron–sulfur (Fe–S) proteins play essential roles in all living organisms. The gastric pathogen Helicobacter pylori relies exclusively on the NIF system for biosynthesis and delivery of Fe–S clusters. Previously characterized components include
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9bc3ffceeefd093bd3ebb11e734bd25
https://pubmed.ncbi.nlm.nih.gov/34031459
https://pubmed.ncbi.nlm.nih.gov/34031459
Publikováno v:
Open Biology, Vol 3, Iss 12 (2013)
Glucarate, an oxidized product of glucose, is a major serum organic acid in humans. Still, its role as a carbon source for a pathogen colonizing hosts has not been studied. We detected high-level expression of a potential glucarate permease encoding
Externí odkaz:
https://doaj.org/article/2755807a943f4da3aa771a3090413a32