Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stéphane G. Paquette"'
Autor:
Stéphane G Paquette, David Banner, Stephen S H Huang, Raquel Almansa, Alberto Leon, Luoling Xu, Jessica Bartoszko, David J Kelvin, Alyson A Kelvin
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005173 (2015)
Seasonal influenza viruses are typically restricted to the human upper respiratory tract whereas influenza viruses with greater pathogenic potential often also target extra-pulmonary organs. Infants, pregnant women, and breastfeeding mothers are high
Externí odkaz:
https://doaj.org/article/d18717a363a84475a29f9db2719183b0
Autor:
Stéphane G Paquette, David Banner, Zhen Zhao, Yuan Fang, Stephen S H Huang, Alberto J Leόn, Derek C K Ng, Raquel Almansa, Ignacio Martin-Loeches, Paula Ramirez, Lorenzo Socias, Ana Loza, Jesus Blanco, Paola Sansonetti, Jordi Rello, David Andaluz, Bianche Shum, Salvatore Rubino, Raul Ortiz de Lejarazu, Dat Tran, Giovanni Delogu, Giovanni Fadda, Sigmund Krajden, Barry B Rubin, Jesús F Bermejo-Martin, Alyson A Kelvin, David J Kelvin
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38214 (2012)
Pandemic H1N1 influenza A (H1N1pdm) is currently a dominant circulating influenza strain worldwide. Severe cases of H1N1pdm infection are characterized by prolonged activation of the immune response, yet the specific role of inflammatory mediators in
Externí odkaz:
https://doaj.org/article/a0136fa9b4ee4281b5c0bf7ac7da5911
Autor:
Alyson A Kelvin, David Banner, Giuliano Silvi, Maria Luisa Moro, Nadir Spataro, Paolo Gaibani, Francesca Cavrini, Anna Pierro, Giada Rossini, Mark J Cameron, Jesus F Bermejo-Martin, Stéphane G Paquette, Luoling Xu, Ali Danesh, Amber Farooqui, Ilaria Borghetto, David J Kelvin, Vittorio Sambri, Salvatore Rubino
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 8, p e1279 (2011)
The Chikungunya virus infection zones have now quickly spread from Africa to parts of Asia, North America and Europe. Originally thought to trigger a disease of only mild symptoms, recently Chikungunya virus caused large-scale fatalities and widespre
Externí odkaz:
https://doaj.org/article/534b3931cd724bb496bccd0c79e5ef73
Autor:
Adnan Khan, Hongxia Chen, Jun Wang, Stéphane G. Paquette, Alyson A. Kelvin, Linxi Huang, Huanjie Ma, Xibing Fang, Nanlan Zheng, Weidong Liu, Amber Farooqui, Jesus F. Bermejo-Martin, Yingmu Cai, Kezhao Hu, Sheng Xu, Chunnuan Lin, Li Zhang, Pengzhou Lin, Zhijian Zhu, Renhua Wu, Weihong Chen, David J. Kelvin, Suwu Wu, Alberto J. Leon, Tiansheng Zeng, Peng Sun, Xiuming Wu, Zhancheng Yao, Yisu Liu
Publikováno v:
New England Journal of Medicine. 374:596-598
This report shows evidence for nosocomial transmission of H7N9 influenza from a patient to two physicians who provided care.
Autor:
David J. Kelvin, Stephen S. H. Huang, Alberto J. Leόn, Stéphane G. Paquette, Alyson A. Kelvin, David Banner, Luoling Xu
Publikováno v:
Virology. :177-183
The major burden of influenza morbidity resides within the elderly population. The challenge managing influenza-associated illness in the elderly is the decline of immune function, where mechanisms leading to immunological senescence have not been el
Autor:
Eva Stefanski, Michael H. Gelb, Stephen S. H. Huang, Ali Danesh, Barry B. Rubin, Alberto J. Leόn, Gérard Lambeau, David Banner, Alyson A. Kelvin, Denis Angoulvant, David J. Kelvin, Norbert Degousee, Stéphane G. Paquette, Hossein Noyan, Mansoor Husain, Clinton S. Robbins
Publikováno v:
Virology
The role of Group X secreted phospholipase A2 (GX-sPLA2) during influenza infection has not been previously investigated. We examined the role of GX-sPLA2 during H1N1 pandemic influenza infection in a GX-sPLA2 gene targeted mouse (GX(-/-)) model and
Autor:
Stephen S. H. Huang, David J. Kelvin, Stéphane G. Paquette, Alyson A. Kelvin, Alberto J. Leon, David Banner
Publikováno v:
The Journal of General Virology
Influenza B viruses have become increasingly more prominent during influenza seasons. Influenza B infection is typically considered a mild disease and receives less attention than influenza A, but has been causing 20 to 50 % of the total influenza in
Autor:
Alyson A. Kelvin, Stephen S. H. Huang, Barry B. Rubin, Thirumagal Kanagasabai, Stéphane G. Paquette, Yuan Fang, David J. Kelvin, David Banner, Louling Xu, Salvatore Rubino, Norbert Degousee, Alberto J. Leon
Publikováno v:
Journal of Virology
Young children are typically considered a high-risk group for disease associated with influenza virus infection. Interestingly, recent clinical reports suggested that young children were the smallest group of cases with severe pandemic 2009 H1N1 (H1N
Autor:
Bernard F. Gibbs, Jaeseung C. Kim, Mark A. Hancock, Hubert Gagnon, James W. Coulton, Maria Plesa, Christopher Ng-Thow-Hing, David S. Rosenblatt, Stéphane G. Paquette
Publikováno v:
Molecular Genetics and Metabolism. 102:139-148
The identification of eight genes involved in inherited cobalamin (Cbl) disorders has provided insight into the complexity of the vitamin B₁₂ trafficking pathway. Detailed knowledge about the structure, interaction, and physiological functions fo
Autor:
Weihong Chen, Pengzhou Lin, Adnan Khan, Yisu Liu, Tiansheng Zeng, Linxi Huang, David J. Kelvin, Suwu Wu, Min Su, Xibin Fang, Stéphane G. Paquette, Yingmu Cai, Li Zhang, Alyson A. Kelvin, Amber Farooqui
Publikováno v:
Antimicrobial Agents and Chemotherapy
The H7N9 influenza virus causes a severe form of disease in humans. Neuraminidase inhibitors, including oral oseltamivir and injectable peramivir, are the first choices of antiviral treatment for such cases; however, the clinical efficacy of these dr