Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Stéphane Chaignepain"'
Autor:
Lilit Simonyan, Mathilde Gonin, James Hanks, Jordan Friedlein, Kevin Dutrec, Hubert Arokium, Akandé Rouchidane Eyitayo, Toukounou Megann Doudy, Stéphane Chaignepain, Stéphen Manon, Laurent Dejean
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
The S184 residue of Bax is the target of several protein kinases regulating cell fate, including AKT. It is well-established that, in cellulo, the substitution of S184 by a non-phosphorylatable residue stimulates both the mitochondrial localization o
Externí odkaz:
https://doaj.org/article/64d6b3d2d0bf4495bb4bb1c2dca1ceac
Autor:
Karl Kempf, Oxana Kempf, Yoan Capello, Christian Molitor, Claire Lescoat, Rana Melhem, Stéphane Chaignepain, Elisabeth Génot, Alexis Groppi, Macha Nikolski, Heidi Halbwirth, Denis Deffieux, Stéphane Quideau
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9724 (2023)
This study aimed at searching for the enzymes that are responsible for the higher hydroxylation of flavonols serving as UV-honey guides for pollinating insects on the petals of Asteraceae flowers. To achieve this aim, an affinity-based chemical prote
Externí odkaz:
https://doaj.org/article/7a4cebb2b42647ef94ae7ae43bad0553
Autor:
Akandé Rouchidane Eyitayo, Axel Boudier-Lemosquet, Stéphane Chaignepain, Muriel Priault, Stéphen Manon
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 876 (2023)
The antiapoptotic protein Bcl-xL is a major regulator of cell death and survival, but many aspects of its functions remain elusive. It is mostly localized in the mitochondrial outer membrane (MOM) owing to its C-terminal hydrophobic α-helix. In orde
Externí odkaz:
https://doaj.org/article/73cb29dd46384292aa08bbbb927f8532
Autor:
Sonia Ciudad, Eduard Puig, Thomas Botzanowski, Moeen Meigooni, Andres S. Arango, Jimmy Do, Maxim Mayzel, Mariam Bayoumi, Stéphane Chaignepain, Giovanni Maglia, Sarah Cianferani, Vladislav Orekhov, Emad Tajkhorshid, Benjamin Bardiaux, Natàlia Carulla
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been proposed to explain neurotoxicity in Alzheimer´s disease. Here authors present the 3D- structure of an Aβ oligomer formed in a membrane mimicking environment and obs
Externí odkaz:
https://doaj.org/article/2c0e9ea1270e440fb213d992e9ac74ae
Autor:
Mohamed S. Benleulmi, Julien Matysiak, Xavier Robert, Csaba Miskey, Eric Mauro, Delphine Lapaillerie, Paul Lesbats, Stéphane Chaignepain, Daniel R. Henriquez, Christina Calmels, Oyindamola Oladosu, Eloïse Thierry, Oscar Leon, Marc Lavigne, Marie-Line Andreola, Olivier Delelis, Zoltán Ivics, Marc Ruff, Patrice Gouet, Vincent Parissi
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background Stable insertion of the retroviral DNA genome into host chromatin requires the functional association between the intasome (integrase·viral DNA complex) and the nucleosome. The data from the literature suggest that direct protein
Externí odkaz:
https://doaj.org/article/62671881f03f4030ac954009c672ddde
Autor:
Adrien Chastel, Delphine Vimont, Stephane Claverol, Marion Zerna, Sacha Bodin, Mathias Berndt, Stéphane Chaignepain, Elif Hindié, Clément Morgat
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1160 (2021)
Background: [68Ga]Ga-RM2 is a potent Gastrin-Releasing Peptide-receptor (GRP-R) antagonist for imaging prostate cancer and breast cancer, currently under clinical evaluation in several specialized centers around the world. Targeted radionuclide thera
Externí odkaz:
https://doaj.org/article/deb395b3dcbd48e196c8fbe2e43d840b
Autor:
Aude Pflieger, Pierre Waffo Teguo, Yorgos Papastamoulis, Stéphane Chaignepain, Frederic Subra, Soundasse Munir, Olivier Delelis, Paul Lesbats, Christina Calmels, Marie-Line Andreola, Jean-Michel Merillon, Corinne Auge-Gouillou, Vincent Parissi
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81184 (2013)
Polynucleotidyl transferases are enzymes involved in several DNA mobility mechanisms in prokaryotes and eukaryotes. Some of them such as retroviral integrases are crucial for pathogenous processes and are therefore good candidates for therapeutic app
Externí odkaz:
https://doaj.org/article/ecc41895c67e45e19fdf74391ff83c35
Autor:
Quideau, Karl Kempf, Oxana Kempf, Yoan Capello, Christian Molitor, Claire Lescoat, Rana Melhem, Stéphane Chaignepain, Elisabeth Génot, Alexis Groppi, Macha Nikolski, Heidi Halbwirth, Denis Deffieux, Stéphane
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9724
This study aimed at searching for the enzymes that are responsible for the higher hydroxylation of flavonols serving as UV-honey guides for pollinating insects on the petals of Asteraceae flowers. To achieve this aim, an affinity-based chemical prote
Publikováno v:
Biophysical Chemistry
Biophysical Chemistry, 2022, 289, ⟨10.1016/j.bpc.2022.106861⟩
Biophysical Chemistry, 2022, 289, ⟨10.1016/j.bpc.2022.106861⟩
Little is known about structural alterations of proteins within the polymeric films of paints. For the first time, hydrogen‑deuterium exchange mass spectrometry (HDX-MS) was implemented to explore the conformational alterations of proteins resultin
Autor:
Agnès Hocquellet, Sophie Lecomte, Mehdi Azouz, François Dole, Stéphane Chaignepain, Antoine Léger, Charlotte Cabanne
Publikováno v:
Protein Expression and Purification
Protein Expression and Purification, 2021, 181, 7 p. ⟨10.1016/j.pep.2021.105830⟩
Protein Expression and Purification, 2021, 181, 7 p. ⟨10.1016/j.pep.2021.105830⟩
Hsp12 is a small heat shock protein of Saccharomyces cerevisiae upregulated in response to various stresses. Non recombinant Hsp12 has been purified and characterized. Using circular dichroism (CD), Isothermal Titration Calorimetry (ITC) and Differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85515e5c065808b4a0810089abceef81
https://hal.archives-ouvertes.fr/hal-03282310
https://hal.archives-ouvertes.fr/hal-03282310