Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Stéphane Bourg"'
Autor:
Samia Aci-Sèche, Stéphane Bourg, Pascal Bonnet, Joseph Rebehmed, Alexandre G. de Brevern, Julien Diharce
Publikováno v:
Data in Brief, Vol 49, Iss , Pp 109386- (2023)
Computational approaches are nowadays largely applied in drug discovery projects. Among these, molecular docking is the most used for hit identification against a drug target protein. However, many scientists in the field shed light on the lack of av
Externí odkaz:
https://doaj.org/article/e7585940b50d4c97ab4ca6ad27f5d0b4
Autor:
Frédéric Buron, Nuno Rodrigues, Thibault Saurat, Marie Aude Hiebel, Stéphane Bourg, Pascal Bonnet, Reine Nehmé, Philippe Morin, Nathalie Percina, Justine Corret, Béatrice Vallée, Remy le Guevel, Marie-Lise Jourdan, Hélène Bénédetti, Sylvain Routier
Publikováno v:
Molecules, Vol 26, Iss 17, p 5349 (2021)
This work describes the synthesis, enzymatic activities on PI3K and mTOR, in silico docking and cellular activities of various uncommon 2,4,7 trisubstituted pyrido[3,2-d]pyrimidines. The series synthesized offers a chemical diversity in C-7 whereas C
Externí odkaz:
https://doaj.org/article/6a0143f187a1484fb74923056d30d307
Autor:
Colin Bournez, Fabrice Carles, Gautier Peyrat, Samia Aci-Sèche, Stéphane Bourg, Christophe Meyer, Pascal Bonnet
Publikováno v:
Molecules, Vol 25, Iss 14, p 3226 (2020)
Since the first approval of a protein kinase inhibitor (PKI) by the Food and Drug Administration (FDA) in 2001, 55 new PKIs have reached the market, and many inhibitors are currently being evaluated in clinical trials. This is a clear indication that
Externí odkaz:
https://doaj.org/article/73d94a131c324dec9ca2a20fd2d03d01
Autor:
Charlotte Rieux, Stéphane Goffinont, Franck Coste, Zahira Tber, Julien Cros, Vincent Roy, Martine Guérin, Virginie Gaudon, Stéphane Bourg, Artur Biela, Vincent Aucagne, Luigi Agrofoglio, Norbert Garnier, Bertrand Castaing
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2058 (2020)
DNA glycosylases are emerging as relevant pharmacological targets in inflammation, cancer and neurodegenerative diseases. Consequently, the search for inhibitors of these enzymes has become a very active research field. As a continuation of previous
Externí odkaz:
https://doaj.org/article/2009aa489feb40818a3558248b0bfc45
Publikováno v:
Molecules, Vol 23, Iss 4, p 908 (2018)
The number of protein kinase inhibitors (PKIs) approved worldwide continues to grow steadily, with 39 drugs approved in the period between 2001 and January 2018. PKIs on the market have been the subject of many reviews, and structure-property relatio
Externí odkaz:
https://doaj.org/article/e4e5f53b155b4dd1bfcf9e91dfabc191
Publikováno v:
Energies, Vol 10, Iss 9, p 1445 (2017)
In this early 21st century, our societies have to face a tremendous and increasing energy need while mitigating the global climate change and preserving the environment. Addressing this challenge requires an energy transition from the current fossil
Externí odkaz:
https://doaj.org/article/e6f619d638a5490b8a9a925eef8b4a64
Autor:
Pascal Bonnet, Philippe Morin, Marie-Lise Jourdan, Reine Nehmé, Hélène Bénédetti, Marie Aude Hiebel, Sylvain Routier, Rémy Le Guével, Béatrice Vallée, Justine Corret, Nathalie Percina, Frédéric Buron, Stéphane Bourg, Thibault Saurat, Nuno Rodrigues
Publikováno v:
Molecules, Vol 26, Iss 5349, p 5349 (2021)
Molecules
Molecules, MDPI, 2021, 26 (17), pp.5349. ⟨10.3390/molecules26175349⟩
Molecules, 2021, 26 (17), pp.5349. ⟨10.3390/molecules26175349⟩
Volume 26
Issue 17
Molecules
Molecules, MDPI, 2021, 26 (17), pp.5349. ⟨10.3390/molecules26175349⟩
Molecules, 2021, 26 (17), pp.5349. ⟨10.3390/molecules26175349⟩
Volume 26
Issue 17
International audience; This work describes the synthesis, enzymatic activities on PI3K and mTOR, in silico docking and cellular activities of various uncommon 2,4,7 trisubstituted pyrido[3,2-d]pyrimidines. The series synthesized offers a chemical di
Autor:
Franck Suzenet, Otmane Bourzikat, Saïd El Kazzouli, Gérald Guillaumet, Pascal Bonnet, Soukaina Faarasse, Stéphane Bourg, Samia Aci-Sèche
Publikováno v:
Advanced Synthesis and Catalysis
Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2021, 363 (16), pp.3937-3945. ⟨10.1002/adsc.202001421⟩
Advanced Synthesis and Catalysis, 2021, 363 (16), pp.3937-3945. ⟨10.1002/adsc.202001421⟩
Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2021, 363 (16), pp.3937-3945. ⟨10.1002/adsc.202001421⟩
Advanced Synthesis and Catalysis, 2021, 363 (16), pp.3937-3945. ⟨10.1002/adsc.202001421⟩
International audience; Direct and site-selective C5 and C7 palladiumcatalyzed C-H arylations of 4-azaindazole N-oxide have been achieved. A bidentate ligand and Pd(OAc)2 catalyst in toluene promoted the activation of C5 position, while a phosphine l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9173430315c8dd6cba389745025e1dd4
https://hal.archives-ouvertes.fr/hal-03416452
https://hal.archives-ouvertes.fr/hal-03416452
Autor:
Giuseppe Modolo, Chris Rhodes, Hitos Galán, Andreas Geist, Manuel Miguirditchian, Christian Ekberg, Robin J. Taylor, Jean-Marc Adnet, Philippe Guilbaud, Stéphane Bourg
Publikováno v:
Separation science and technology 56(11), 1866-1881 (2021). doi:10.1080/01496395.2020.1795680
The hydrometallurgical separation concepts for the heterogeneous recycling of irradiatednuclear fuel developed within European collaborative projects are presented and discussed. Most ofthese concepts were developed within European collaborative proj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ffce77196c1349b8f163c95c3c5192
https://hdl.handle.net/2128/27928
https://hdl.handle.net/2128/27928