Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Stéphane, Manenti"'
Autor:
Charly Courdy, Loïc Platteeuw, Charlotte Ducau, Isabelle De Araujo, Emeline Boet, Ambrine Sahal, Estelle Saland, Valérie Edmond, Suzanne Tavitian, Sarah Bertoli, Pierre Cougoul, Fanny Granat, Laura Poillet, Caroline Marty, Isabelle Plo, Jean-Emmanuel Sarry, Stéphane Manenti, Véronique Mansat-De Mas, Carine Joffre
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The Janus kinase 2 (JAK2)-driven myeloproliferative neoplasms (MPNs) are chronic malignancies associated with high-risk complications and suboptimal responses to JAK inhibitors such as ruxolitinib. A better understanding of cellular changes
Externí odkaz:
https://doaj.org/article/f1e0dd6471384291bb94a7aca671d64a
Autor:
Claudie Bosc, Nicolas Broin, Marjorie Fanjul, Estelle Saland, Thomas Farge, Charly Courdy, Aurélie Batut, Rawand Masoud, Clément Larrue, Sarah Skuli, Nicolas Espagnolle, Jean-Christophe Pagès, Alice Carrier, Frédéric Bost, Justine Bertrand-Michel, Jérôme Tamburini, Christian Récher, Sarah Bertoli, Véronique Mansat-De Mas, Stéphane Manenti, Jean-Emmanuel Sarry, Carine Joffre
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
How autophagy supports tumor cell metabolism is not fully clear. Here, the authors show that autophagy regulates lipid availability to support mitochondrial oxidative metabolism through mitochondria-endoplasmic reticulum contact sites, necessary for
Externí odkaz:
https://doaj.org/article/8cc02f2742d84833a052afbcc115d3a3
Autor:
Christian Récher, Jean Emmanuel Sarry, Stéphane Manenti, Jérôme Tamburini, Marie-Anne Hospital, Véronique Mansat-De Mas, Eric Delabesse, Nizar Serhan, François Vergez, Estelle Saland, Clément Larrue
This file contains additional figures that enrich results presented in the main manuscript. We evaluated the impact of the 2-DG on the expression of both wild-type FLT3 and KIT. Then, we excluded a potential role for cellular protein degradation path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08494bdebd508c623b513fc117300b99
https://doi.org/10.1158/1535-7163.22506504.v1
https://doi.org/10.1158/1535-7163.22506504.v1
Autor:
Christian Récher, Jean Emmanuel Sarry, Stéphane Manenti, Jérôme Tamburini, Marie-Anne Hospital, Véronique Mansat-De Mas, Eric Delabesse, Nizar Serhan, François Vergez, Estelle Saland, Clément Larrue
We assessed the antileukemic activity of 2-deoxy-d-glucose (2-DG) through the modulation of expression of receptor tyrosine kinases (RTK) commonly mutated in acute myeloid leukemia (AML). We used human leukemic cell lines cells, both in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122bb55a61312cad68d5180738cbfea1
https://doi.org/10.1158/1535-7163.c.6538419.v1
https://doi.org/10.1158/1535-7163.c.6538419.v1
Autor:
Bernard Ducommun, Cécile Demur, Christian Recher, Stéphane Manenti, Véronique Mansat-De Mas, Naïs Prade, Christine Didier, Cindy Cavelier
Supplementary Figure 3 from Constitutive Activation of the DNA Damage Signaling Pathway in Acute Myeloid Leukemia with Complex Karyotype: Potential Importance for Checkpoint Targeting Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be76b1354cb52f21a8ef0815151c625
https://doi.org/10.1158/0008-5472.22379705.v1
https://doi.org/10.1158/0008-5472.22379705.v1
Autor:
Bernard Ducommun, Cécile Demur, Christian Recher, Stéphane Manenti, Véronique Mansat-De Mas, Naïs Prade, Christine Didier, Cindy Cavelier
Supplementary Figure 5 from Constitutive Activation of the DNA Damage Signaling Pathway in Acute Myeloid Leukemia with Complex Karyotype: Potential Importance for Checkpoint Targeting Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79d224652c58c34bf961c9d0c17996f
https://doi.org/10.1158/0008-5472.22379696
https://doi.org/10.1158/0008-5472.22379696
Autor:
Bernard Ducommun, Cécile Demur, Christian Recher, Stéphane Manenti, Véronique Mansat-De Mas, Naïs Prade, Christine Didier, Cindy Cavelier
Genomic instability in solid tumors participates in the oncogenetic process and is associated with the activation of the DNA damage response pathway. Here, we report the activation of the constitutive DNA damage and checkpoint pathway associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9caf5f6be8f1f6bc375782c551e279e
https://doi.org/10.1158/0008-5472.c.6499331.v1
https://doi.org/10.1158/0008-5472.c.6499331.v1
Autor:
Bernard Ducommun, Cécile Demur, Christian Recher, Stéphane Manenti, Véronique Mansat-De Mas, Naïs Prade, Christine Didier, Cindy Cavelier
Supplementary Figure 4 from Constitutive Activation of the DNA Damage Signaling Pathway in Acute Myeloid Leukemia with Complex Karyotype: Potential Importance for Checkpoint Targeting Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb049cd5b5b48ff47271819c1279eb46
https://doi.org/10.1158/0008-5472.22379702
https://doi.org/10.1158/0008-5472.22379702
Autor:
Bernard Ducommun, Cécile Demur, Christian Recher, Stéphane Manenti, Véronique Mansat-De Mas, Naïs Prade, Christine Didier, Cindy Cavelier
Supplementary Figure 2 from Constitutive Activation of the DNA Damage Signaling Pathway in Acute Myeloid Leukemia with Complex Karyotype: Potential Importance for Checkpoint Targeting Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b414e6cce8cc06e4c37c4330dd061ae
https://doi.org/10.1158/0008-5472.22379708
https://doi.org/10.1158/0008-5472.22379708
Publikováno v:
Molecular & Cellular Oncology, Vol 4, Iss 5 (2017)
Resistance of acute myeloid leukemia to current therapies leads to frequent relapses. Identification of molecular mechanisms involved in chemoresistance constitutes a key challenge to define new therapeutic concepts. Here, we show that the ATR/CHK1 p
Externí odkaz:
https://doaj.org/article/c39976d70e79476c93587d98544c7e03